- dental development and anomalies
- Orthodontics and Dentofacial Orthopedics
- TGF-β signaling in diseases
- Temporomandibular Joint Disorders
- Scheduling and Optimization Algorithms
- Bone and Dental Protein Studies
- Advanced Manufacturing and Logistics Optimization
- Cancer-related molecular mechanisms research
- Dental Implant Techniques and Outcomes
- Assembly Line Balancing Optimization
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
Tongji University
2008-2020
Mandibular prognathism (MP) is regarded as a craniofacial deformity resulting from the combined effects of environmental and genetic factors, while genetically predetermined component considered to play an important role develop MP. Although linkage association studies for MP have identified multiple strongly associated regions genes, causal genes variants responsible remain largely undetermined. To address this, we performed targeted sequencing 396 selected previous well pathways related...
This study aims to replicate the phenotype of Ltbp1 knockout mice in zebrafish, and address function LTBP1 craniofacial development.Whole mount situ hybridization (WISH) ltbp1 was performed at critical periods zebrafish development explore spatial-temporal expression pattern. Furthermore, we generated morpholino based knockdown model phenotype.WISH mainly detected mandibular jaw region, brain trunk, internal organs such as pancreas gallbladder. And colocalized with both sox9a ckma region....
A dynamic classified work-in-process (DC-WIP) release rule is proposed to meet the requirement of multi-objective optimization for semiconductor manufacturing line with multiple orders. It based on fuzzy algorithm, theory constraints and feedback control. DC-WIP consists determination order priority, rate WIP level setting. By using a simulation model essential characteristics line, was compared other traditional rules. The results show that prior these rules cycle time, on-time-delivery...