- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Graphene research and applications
- Graphene and Nanomaterials Applications
- 2D Materials and Applications
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanowire Synthesis and Applications
- Molecular Junctions and Nanostructures
- Carbon Nanotubes in Composites
- Advanced Biosensing Techniques and Applications
- Extracellular vesicles in disease
- Supramolecular Self-Assembly in Materials
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Analytical Chemistry and Sensors
Hubei University of Chinese Medicine
2014-2025
Wuhan University
2017-2024
Renmin Hospital of Wuhan University
2017-2024
A reduced graphene oxide (R-GO)-based field-effect transistor (FET) biosensor used for ultrasensitive label-free detection of DNA via peptide nucleic acid (PNA)-DNA hybridization is reported. In this work, R-GO was prepared by reduction GO with hydrazine, and the FET fabricated drop-casting suspension onto sensor surface. PNA instead as capture probe employed, performed through PNA-DNA biosensor. The limit low 100 fM achieved, which 1 order magnitude lower than that previously reported based...
Breast cancer has been ranked the first malignant tumor in women, and with incidence of it increasing all over world, early screening can effectively reduce mortality improve cure rate. MiRNAs, as potential biomarkers, play an important role diagnosis prognosis monitoring breast cancer. However, since miRNAs, low concentration, are matrix serum or plasma, accurately detecting miRNAs without a label plasma is challenging. Herein, we proposed biosensor combination nanomaterial for reduced...
A MoS<sub>2</sub>-based sensor was developed to detect miR-21 in serum for early diagnosis of breast cancer.
<title>Abstract</title> The photothermal conversion properties of tellurium (Te) nanoparticles have been extensively investigated, rendering them a promising candidate for tumor therapy. However, there is still room improvement in the development efficient Te-based drug delivery systems. Here, Te are mineralized with bioactive molecules within attenuated <italic>Salmonella</italic> (S-Te), which subsequently taken up by macrophages (RAW264.7) to construct double-camouflaged platform (RS-Te)....
Field-effect transistor (FET)-based biosensors exhibit excellent performance characteristics such as small size, ease of mass production, high versatility, and comparably low cost. In recent years, numerous FET based on various nanomaterials including silicon nanowires, carbon nanotubes, graphene, transition metal dichalcogenides have been developed to detect a wide range biomarkers that play crucial role in early disease diagnosis, therapeutic monitoring prognostic assessment. This review...
The photothermal conversion properties of tellurium (Te) nanoparticles have been extensively investigated, rendering them a promising candidate for tumor therapy. However, there is still room improvement in the development efficient Te-based drug delivery systems. Here, Te are mineralized with bioactive molecules within attenuated Salmonella (S-Te), which subsequently taken up by macrophages (RAW264.7) to construct double-camouflaged platform (RS-Te). Remarkably, RS-Te retains superior under...