A5083488853- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Cardiac tumors and thrombi
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular Anomalies and Treatments
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- RNA Research and Splicing
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- GDF15 and Related Biomarkers
- Congenital Heart Disease Studies
- Healthcare Policy and Management
- RNA and protein synthesis mechanisms
- Blood disorders and treatments
- MicroRNA in disease regulation
- Methemoglobinemia and Tumor Lysis Syndrome
- Healthcare Systems and Reforms
- Trauma Management and Diagnosis
- Aortic aneurysm repair treatments
- Cerebrovascular and Carotid Artery Diseases
Narayana Health
2005-2024
Institute of Medical Sciences
2005
Multiple muscular ventricular septal defects (VSDs) are surgically challenging and its management remains controversial. We present a technique of surgical repair for VSDs, which includes exposure detection these has excellent clinical outcomes.We have analysed consecutive patients who underwent isolated multiple VSDs under cardiopulmonary bypass over 16-year period (from January 2001 to November 2016) in single centre from the southern part India. These were accessed through right atrium...
Massive pulmonary hemorrhage during thromboendarterectomy (PTE) can be managed by a conservative approach with mechanical ventilatory support, positive end-expiratory pressure, lung isolation, reversal of heparin, and correct coagulopathy. We present three challenging cases that developed intrapulmonary during/after PTE successfully. The first patient had bleeding from the bronchial artery right internal mammary collaterals, which was coil-embolization. second breach in blood airway barrier...
The emergence of COVID-19 has impacted heart transplantation worldwide. pandemic donor availability and also raised issues safety receipients surgical teams. In these recommendations, the Indian Society Heart Lung Transplantation (INSHLT) discussed related to testing recipient as well INSHLT recommends once consent for organ donation is obtained both receipient. high-resolution computed tomography chest before donation, especially lung donation.
An alternative method of maintaining carotid perfusion during combined endarterectomy and off-pump coronary artery bypass grafting involves insertion a cannula in the ascending aorta after median sternotomy. This is connected to cannula, distal end which inserted into beyond arteriotomy. technique aortico-carotid shunting was utilized nine patients who underwent successful grafting.
Pulmonary endarterectomy is potential curative therapy for chronic thromboembolic pulmonary hypertension patients. Here, we present our experience with spanning 17 years and detail management strategy.This a single-centre retrospective study conducted on patients who underwent at centre across years.Between 2004 2020, 591 endarterectomy. Amongst them 429 (72.4%) were males male to female ratio of 2.6:1, the median age was 38 (range, 14-73) years. The length hospital stay 11 days (IQR, 8-16)....
Background: The manufacturer recommended dose of Mycophenolate Mofetil (MMF) [600 mg/m2 twice daily orally] is known to cause adverse effects (AE) blood dyscrasia especially agranulocytosis. A lower initial MMF reported limit AE while still maintaining acceptable patient and graft outcomes after heart transplantation (HT). Methods: We present a case an adolescent who developed significant febrile neutropenia on low orthotopic HT. Results: 14-year old boy underwent HT for dilated...
In performing pulmonary endarterectomy (PEA) for a patient with chronic thromboembolic hypertension (CTEPH), we encountered methemoglobinemia that was unmasked by hypothermia while on cardiopulmonary bypass (CPB). The dapsone therapy antiphospholipid antibody syndrome had developed acquired went undiagnosed because her cyanosis believed to be due CTEPH and the resulting ventilation-perfusion (V/Q) mismatch. Although pharmacological triggers methemoglobin are well known, causation is not...
Background: A 17-year old boy with Ebstein’s anomaly of tricuspid valve, severe biventricular dysfunction and class IV heart failure was admitted for pre-heart transplant evaluation (HT). Three days later, he had sudden cardiac arrest revived CPR placed on VA ECMO. Attempts at ECMO wean were unsuccessful due to RV dysfunction. Pre-transplant work up showed acute kidney injury (AKI) otherwise deemed an eligible recipient emergent transplantation. Luminex® single antigen bead test negative...
Background: Heart transplant remains the gold standard for treatment of end-stage heart failure. The most common method donor preservation, during transport, is "triple-bag technique" with static cold storage (SCS). safe duration (ischemic time) a SCS 4 h shortest among all transplantable solid organs. One factors determining heart's quality and transport organ. This study identified centers which perform transplants routinely (≥7 per year) past 3 years compared differences between their...
Background The inflammation or degeneration of the heart muscle myocarditis may be fatal. This disease often goes undetected. It also disguise itself as ischemic valvular hypertensive disease. Here we report eight cases acute fulminant viral suffering from low cardiac output ARDS Acute respiratory distress syndrome formation and successfully treated with ECMO Extra corporeal membrane oxygenation.Methodology All were admitted in emergency coronary care unit severe poor hemodynamics ECHO...
Heart failure (HF) is a leading cause of death worldwide and research focused on human cardiac tissue provides insights into underlying disease mechanisms. In this study, we performed transcriptome analyses from 21 South Asian (SA) HF patients compared them with controls without HF. The aim was to i) probe dysregulated genes pathways in ii) identify core gene signature conserved across etiologies ethnicities. Gene set enrichment (DGs) showed positive Ontology terms for ECM remodelling,...