- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Plant Pathogens and Fungal Diseases
- Aquaculture disease management and microbiota
- Probiotics and Fermented Foods
- Bacteriophages and microbial interactions
- Identification and Quantification in Food
- Enzyme Production and Characterization
- X-ray Diffraction in Crystallography
- Plant Disease Resistance and Genetics
- Crystallization and Solubility Studies
- Advanced biosensing and bioanalysis techniques
- Plant Pathogenic Bacteria Studies
- Microbial bioremediation and biosurfactants
- Banana Cultivation and Research
- Oral microbiology and periodontitis research
- Gut microbiota and health
- Microbial Natural Products and Biosynthesis
- Biosensors and Analytical Detection
- Diatoms and Algae Research
- Synthesis of β-Lactam Compounds
- Algal biology and biofuel production
- Plant-Microbe Interactions and Immunity
- Yeasts and Rust Fungi Studies
- Antimicrobial Peptides and Activities
Institute of Microbial Technology
2016-2025
Council of Scientific and Industrial Research
2013-2024
Academy of Scientific and Innovative Research
2018-2021
Centre for Cellular and Molecular Biology
2013
Abstract Background Gold nanoparticles (AuNPs) have found wide range of applications in electronics, biomedical engineering, and chemistry owing to their exceptional opto-electrical properties. Biological synthesis gold by using plant extracts microbes received profound interest recent times potential produce with varied shape, size morphology. Marine microorganisms are unique tolerate high salt concentration can evade toxicity different metal ions. However, these marine not sufficiently...
Biosurfactants are potential biomolecules that have extensive utilization in cosmetics, medicines, bioremediation and processed foods. Yeast produced biosurfactants offer thermal resistance, antioxidant activity, no risk of pathogenicity, illustrating their promising use food formulations. The present study is aimed to assess biosurfactant screened from a novel yeast inhibition against spoilage fungi. A asexual ascomycetes strain CIG-6A T producing biosurfactant, was isolated the gut...
Abstract Background Increasing multidrug-resistance in bacteria resulted a greater need to find alternative antimicrobial substances that can be used for clinical applications or preservation of food and dairy products. Research on peptides including lipopeptides exhibiting both narrow broad spectrum inhibition activities is increasing the recent past. Therefore, present study was aimed at isolation characterization lipopeptide producing bacterial strains from fecal contaminated soil sample....
Abstract A bacterial strain producing two antimicrobial peptides was isolated from a rhizosphere soil sample and identified as Bacillus subtilis based on both phenotypic 16S rRNA gene sequence phylogenetic analysis. It grew optimally up to 14% NaCl produced peptide within 24 h of growth. The were purified using combination chemical extraction chromatographic techniques. MALDI-TOF analysis HPLC fractions revealed that the SK.DU.4 secreted bacteriocin-like with molecular mass 5323.9 Da...
Here, we evaluated any beneficial effects of a potential probiotic bacterial strain (Lactobacillus plantarum MTCC 9510) in two different stress paradigms mice. Lactobacillus 9510 (2 × 1010 CFU per mice) was supplemented to male Swiss albino mice either subjected chronic unpredictable mild or sleep deprivation (SD) stress. Various behavioural and biochemical tests along with selected gut abundances were determined. supplementation prevented stress‐induced despair (depression, anxiety,...
Carotenoids have important functions in bacteria, ranging from harvesting light energy to neutralizing oxidants and acting as virulence factors. However, information pertaining the carotenoids is scattered throughout literature. Furthermore, about genes/proteins involved biosynthesis of has tremendously increased post-genomic era. A web server providing microbial a structured manner required will be valuable resource for scientific community working with carotenoids.Here, we created manually...
The present study demonstrates exopolysaccharide production by an osmotolerant marine isolate and also describes further application of the purified polysaccharide for colloidal suspension silver nanoparticles with narrow size distribution. Phylogenetic analysis based on 16S r RNA gene sequencing revealed close affinity to Alteromonas macleodii. Unlike earlier reports, where glucose was used as carbon source, lactose found be most suitable substrate production. strain capable producing 23.4...
Sewage waste represents an ecosystem of complex and interactive microbial consortia which proliferate with different kinetics according to their individual genetic as well metabolic potential. We performed metagenomic shotgun sequencing on Ion-Torrent platform, explore the community structure, biological interactions associated functional capacity pre-treated/raw sludge (RS) post-treated/dried (DS) wastewater treatment plant. Bacterial phylotypes belonging Epsilonproteobacteria (∼45.80%)...
Lactiplantibacillus plantarum MTCC 2621 is a well-characterized probiotic strain and reported to possess many health benefits. However, the wound healing potential of this yet be explored. Here, we have assessed antibacterial, antioxidant, activities cell-free supernatant (Lp2621). Lp2621 exhibited excellent antibacterial activity against indicator bacteria in agar well diffusion assay. did not show any hemolytic activity. The safety gel was established using skin irritation assay BALB/c...
Abstract Antibiotic-resistance is ever growing burden on our society for the past many years. Many synthetic chemistry approaches and rational drug-design have been unable to pace up tackle this problem. Natural resources, more specifically, microbial diversity, other hand, make a traditional still best platform search new chemical scaffolds compounds. Here, we report antimicrobial characteristics of novel bacterial isolate from salt lake in India. We screened isolates their inhibitory...
This study was aimed to determine antimicrobial and antiviral activity of a novel lanthipeptide from Brevibacillus sp. for disinfectant application.The peptide (AMP) produced by bacterial strain AF8 identified as member the genus representing species. Whole genome sequence analysis using BAGEL putative complete biosynthetic gene cluster involved in synthesis. The deduced amino acid named brevicillin, showed >30% similarity with epidermin. Mass determined MALDI-MS Q-TOF suggested...
Abstract Herein, trans‐ and cis‐ azetidin‐2‐ones 3–6 were strategically synthesized, capitalizing on the bioactivity of indole pharmacophore, followed by a comprehensive characterization using diverse array spectroscopic techniques. The sixteen examined for antimicrobial activities against both Gram‐negative ( P. aeruginosa , E. coli A. baumannii ) Gram‐positive bacteria (S . aureus, faecium, B. cereus ), as well C. albicans tropicalis fungal strains. highly potent compounds 5 6 b d...
A Gram-positive, yellow-pigmented, actinobacterial strain, DW152(T), was isolated from a dairy industry effluent treatment plant. 16S rRNA gene sequence analysis indicated that strain DW152(T) exhibited low similarity with many species validly published names belonging to the genera Micrococcus and Arthrobacter. However, phenotypic properties including chemotaxonomic markers affiliated genus Micrococcus. Strain had ai-C(15:0) i-C(15:0) as major cellular fatty acids, MK-8(H(2)) menaquinone....
A novel Gram-stain-negative, rod-shaped, motile bacterium, designated strain AK21(T), was isolated from coastal surface sea water at Visakhapatnam, India. The positive for oxidase, catalase, lipase, L-proline arylamidase and tyrosine activities. predominant fatty acids were C12:0, C12:0 3-OH, C16:0, C16:1ω9c, C18:1ω9c summed feature 3 (C16:1ω7c and/or iso-C15:0 2-OH). polar lipids diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylglycerol, one unidentified aminophospholipid, two...