A5102941295- RNA modifications and cancer
- Immunodeficiency and Autoimmune Disorders
- interferon and immune responses
- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- Eosinophilic Esophagitis
Nanchang University
2020-2022
The outer membrane vesicles (OMVs) secreted by Helicobacter pylori contain various bacterial components, such as proteins, phospholipids, toxins, and nucleic acids, including small noncoding RNA (sncRNA), which have regulatory functions in cell envelope structure, metabolism, communication, biofilm formation, virulence. We previously showed that knocking out sncRNAs sR-989262 sR-2509025 at the cellular level increased interleukin 8 (IL-8) levels mice exposed to OMVs.
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of family Picornaviridae and can cause acute acinar pancreatitis in adults. However, molecular mechanisms pathogenesis underlying CVB3-induced have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, confocal microscopy, show Menage a trois 1 (MAT1), subunit Cdk-Activating...
Abstract Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of family Picornaviridae and can cause acute acinar pancreatitis in adults. However, molecular mechanisms pathogenesis underlying CVB3-induced have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, confocal microscopy, show Menage a trois 1 (MAT1), subunit...