Zhicheng Guo

ORCID: 0000-0003-4485-2486
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About
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Research Areas
  • Aquaculture Nutrition and Growth
  • Marine Bivalve and Aquaculture Studies
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • Helicobacter pylori-related gastroenterology studies
  • Cancer Genomics and Diagnostics
  • Immunotherapy and Immune Responses
  • Plant Reproductive Biology
  • Virus-based gene therapy research
  • Physical Activity and Health
  • Epigenetics and DNA Methylation
  • Aquaculture disease management and microbiota
  • Natural Language Processing Techniques
  • Eosinophilic Esophagitis
  • Cancer-related gene regulation
  • Topic Modeling
  • Molecular Biology Techniques and Applications
  • Antioxidant Activity and Oxidative Stress
  • Immune Response and Inflammation
  • Parasites and Host Interactions
  • Multimodal Machine Learning Applications
  • Hydrogels: synthesis, properties, applications
  • biodegradable polymer synthesis and properties
  • Genetic and Kidney Cyst Diseases
  • Cancer Research and Treatments

Tsinghua University
2024

Craft Engineering Associates (United States)
2024

The University of Sydney
2024

Dalian Ocean University
2021-2023

Tianjin University
2022

Harvard University
2022

Duke University
2022

Beth Israel Deaconess Medical Center
2022

Qingdao National Laboratory for Marine Science and Technology
2022

Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2022

Tourism is a critical sustainable social and economic activity that can empower local communities. The current study strived to explore decisive factors might be used it promotes environmental protection. Governments worldwide employ improve conservation the tourism sector. There need sponsor more publications on environment provide rigor, insight, significance. also address impacts, including greenhouse gases for airlines, liquid wastes cruise ships, water energy urban hotels, vegetation...

10.35784/preko.5414 article EN cc-by-sa Problemy Ekorozwoju 2024-01-08

The noble scallop Chlamys nobilis Reeve displays polymorphism in shell and muscle colors. Previous research showed that the orange scallops with had a significantly higher carotenoid content than brown ones white muscle. There is currently need to identify candidate genes associated carotenoid-based coloration. In present study, 454 GS-FLX sequencing of transcriptome yielded 1,181,060 clean sequence reads, which were assembled into 49,717 isotigs, leaving 110,158 reads as singletons. Of...

10.1186/s12864-015-1241-x article EN cc-by BMC Genomics 2015-02-04

To improve the therapeutic effect of a hydrogel on damaged tissue, series hydroxybutyl chitosan (HBC) and poly(sulfobetaine methacrylate) (PSBMA) composite hydrogels (HBC-PSB) with thermosensitivity, self-healing, antibiofouling, synergistic antibacterial activity are prepared by mechanical blending. The electrostatic interaction among PSBMA hydrophobic association HBC main drive force to form full physically crosslinked hydrogel. can avoid aggregation precipitation caused intermolecular...

10.1039/d2tb00027j article EN Journal of Materials Chemistry B 2022-01-01

To investigate the effects of Tribulus terrestris (TT) extracts on muscle mass, damage, and anaerobic performances trained male boxers its mechanisms: roles plasma androgen, insulin growth factor 1 (IGF-1), IGF-1 binding protein-3 (IGFBP-3). Fifteen were divided into exercise group (E, n = 7) plus TT (E + TT, 8). The 2 groups both undertook 3-week high-intensity high-volume trainings separated by a 4-week rest. (1250 mg/day) orally administered in E group. extract compositions detected...

10.1016/j.jshs.2015.12.003 article EN cc-by-nc-nd Journal of sport and health science/Journal of Sport and Health Science 2015-12-16

Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential in important physiological processes. However, the endogenous PUFA biosynthesis pathway is poorly understood marine bivalves. Previously, a acyl desaturase (Fad) with Δ5 activity was functionally characterized and an elongase termed Elovl2/5 reported to efficiently elongate 18:2n–6 18:3n–3 20:2n–6 20:3n–3 respectively Chlamys nobilis. In this study, another Fad were identified. Functional characterization recombinant yeast...

10.1021/jf504648f article EN Journal of Agricultural and Food Chemistry 2014-12-02

The outer membrane vesicles (OMVs) secreted by Helicobacter pylori contain various bacterial components, such as proteins, phospholipids, toxins, and nucleic acids, including small noncoding RNA (sncRNA), which have regulatory functions in cell envelope structure, metabolism, communication, biofilm formation, virulence. We previously showed that knocking out sncRNAs sR-989262 sR-2509025 at the cellular level increased interleukin 8 (IL-8) levels mice exposed to OMVs.

10.1128/iai.00267-22 article EN Infection and Immunity 2022-07-21

Abstract Background Despite frequent discussions on the link between physical and mental health, specific impact of fitness well-being is yet to be fully established. Method This study, carried out January 2022 August 2023, involved 4,484 Chinese University students from eight universities located in various regions China. It aimed examine association psychological well-being. Descriptive statistics, t-tests, logistic regression were used analyze indicators (e.g., Body Mass Index (BMI),...

10.1186/s12889-024-18841-y article EN cc-by BMC Public Health 2024-05-21

Intramuscular fat content is an important factor that determines meat quality in pigs. In recent years, epigenetic regulation has increasingly studied the physiological model of intramuscular fat. Although long noncoding RNAs (lncRNAs) play essential roles various biological processes, their role deposition pigs remains largely unknown. this study, preadipocytes longissimus dorsi and semitendinosus Large White were isolated induced into adipogenic differentiation vitro. High-throughput...

10.1080/10495398.2023.2176319 article EN Animal Biotechnology 2023-02-15

10.1109/cvpr52733.2024.01355 article EN 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) 2024-06-16

Objective: The aim of this study was to compare the clinical efficacy and safety retroperitoneal laparoscopic open surgery for correction retrocaval ureter. Patients methods: Clinical data 14 patients with ureter were analyzed retrospectively. Among them, nine treated by surgical therapy five surgery. transpositioned a normal anatomic position followed intracorporeal uretero ureteric anastomosis. Results: Open successfully performed in cases. mean time 95.6±22.0 min, blood loss 108.6±34.5...

10.2147/tcrm.s139113 article EN cc-by-nc Therapeutics and Clinical Risk Management 2017-06-01

Peanut worm, Sipunculus nudus, is an important economic and ecological species. This study aims to characterize differences in the coelomic fluid of S. nudus between breeding nonbreeding seasons. Animals were obtained July November. The diameter oocytes was measured analyzed. Results showed that number formed a primary peak at approximately 160 μm July, while almost all below 50 A metabolomics approach based on LC–MS GC–MS used investigate gain insights into mechanisms underlying oocyte...

10.1016/j.aqrep.2019.100271 article EN cc-by-nc-nd Aquaculture Reports 2020-01-09

In intensive care units (ICUs), critically ill patients are monitored with electroencephalograms (EEGs) to prevent serious brain injury. The number of who can be is constrained by the availability trained physicians read EEGs, and EEG interpretation subjective prone inter-observer variability. Automated deep learning systems for could reduce human bias accelerate diagnostic process. However, black box models untrustworthy, difficult troubleshoot, lack accountability in real-world...

10.48550/arxiv.2211.05207 preprint EN other-oa arXiv (Cornell University) 2022-01-01

Despite having powerful reasoning and inference capabilities, Large Language Models (LLMs) still need external tools to acquire real-time information retrieval or domain-specific expertise solve complex tasks, which is referred as tool learning. Existing learning methods primarily rely on tuning with expert trajectories, focusing token-sequence from a linguistic perspective. However, there are several challenges: 1) imitating static trajectories limits their ability generalize new tasks. 2)...

10.48550/arxiv.2410.07745 preprint EN arXiv (Cornell University) 2024-10-10
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