Sebastian Szklener

ORCID: 0000-0002-7379-963X
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About
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Research Areas
  • Technology Use by Older Adults
  • Myasthenia Gravis and Thymoma
  • Epilepsy research and treatment
  • Orthopedic Surgery and Rehabilitation
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neurosurgical Procedures and Complications
  • Intracranial Aneurysms: Treatment and Complications
  • Pharmacological Effects and Toxicity Studies
  • Parkinson's Disease and Spinal Disorders
  • Social Robot Interaction and HRI
  • Peripheral Nerve Disorders
  • Antifungal resistance and susceptibility
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver physiology and pathology
  • Infectious Encephalopathies and Encephalitis
  • Neonatal and fetal brain pathology
  • Peripheral Neuropathies and Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Musculoskeletal pain and rehabilitation
  • Multiple Sclerosis Research Studies
  • Neurological disorders and treatments
  • Cancer Treatment and Pharmacology
  • Motor Control and Adaptation
  • AI in Service Interactions
  • Long-Term Effects of COVID-19

Medical University of Lublin
2015-2022

Objective: We focused on identifying the requirements and needs of people suffering from Alzheimer disease early dementia stages with relation to robotic assistants. Methods: Based focus groups performed in two centres (Poland Spain) we created surveys for medical staff, patients, caregivers, including: functional requirements; human-robot interaction, design assistant user acceptance aspects. Using Likert scale analysis made basis frequency survey responses identified users' as high,...

10.3389/fneur.2017.00228 article EN cc-by Frontiers in Neurology 2017-06-01

The aim of the present study is to results assessment clinical application robotic assistant for patients suffering from mild cognitive impairments (MCI) and Alzheimer Disease (AD). human-robot interaction (HRI) evaluation approach taken within a novelty in field social robotics. proposed functionalities are based on end-user perception attractiveness, usability potential societal impact device. methods applied consist User Experience Questionnaire (UEQ), AttrakDiff inventory tailored...

10.3389/fneur.2018.00392 article EN cc-by Frontiers in Neurology 2018-06-01

Objective The purpose of this study was to identify prognostic factors and build the predictive model based on poor-grade subarachnoid haemorrhage (SAH) population received only supportive symptomatic treatment. Design Prospective observational cohort study. Setting Intensive care unit at Clinical Department Neurology. Participants A total 101 patients with spontaneous SAH disqualified from neurosurgical operative treatment due poor clinical condition. Data were collected over a 9-year...

10.1136/bmjopen-2015-007795 article EN cc-by-nc BMJ Open 2015-06-01

The aim of this study was to assess the effectiveness cladribine treatments in a population patients with refractory myasthenia gravis (MG).In prospective open-label MG, 13 received at baseline repetitive cycles driven by clinical response. A Myasthenia Gravis Composite (MGC) score obtained and standard dose steroids administered.A total 11 achieved significant improvement MGC during their therapy. mean declined from 15.1 6.3 points within 4 months observation. dosage prednisolone 9.5 1.9...

10.1111/ene.14124 article EN European Journal of Neurology 2019-11-09

Cladribine is currently registered as a 10-milligram tablet formulation with fixed cumulative dosage of 3.5 mg/kg over 2 years. It important to investigate if an increased may lead further clinical stability preserved safety. This study used off-label subcutaneous (s.c.) cladribine and compared outcomes (Expanded Disability Status Scale (EDSS) scores disease progression) between 52 relapsing multiple sclerosis (RMS) patients receiving different s.c. dosing regimens up 20 years follow-up. The...

10.3390/jcm10215207 article EN Journal of Clinical Medicine 2021-11-08

Acute repetitive seizures (ARS) pose a risk of hospital admission with status epilepticus and mortality threat, which underscores the need for early prediction clinical course. Unfortunately, little attention has been given to ARS in this context, even though we possess appropriate predictive tools stages epilepticus. Therefore, main aim study was assess prognostic value Status Epilepticus Severity Score (STESS) population patients ARS. The included 200 patients. Almost half had achieved...

10.1111/epi.14061 article EN Epilepsia 2018-03-30

Robotic technologies have the potential to give support in activities of daily living (ADLs) AD patients. In this scope, RAMCIP project is aimed develop a social robot that will provide assistance patients early stages (mild cognitive impairment or mild dementia) at their homes. This process comprises acceptance service among end-users and caregivers. Here, our objective compare agreement between perception users caregivers possibility receiving from ADLs, attitude towards technology. We...

10.1016/j.jalz.2017.06.2192 article EN Alzheimer s & Dementia 2017-07-01

The most frequent type of primary liver cancer is hepatocellular carcinoma (HCC). Although HCC not the cancer, it characterized by high mortality – 5-year survival rate 6,9%. In recent decades there was only one molecule available in treatment (sorafenib). However, past few years have been advances treatment. Nowadays, new generation tyrosine kinase inhibitors, check point inhibitors and anti-angiogenesis drugs are available. All those studies were analyzed outcome context monotherapy or...

10.5603/njo.2021.0073 article EN cc-by-nc-nd Nowotwory Journal of Oncology 2021-12-06

<sec> <title>BACKGROUND</title> Carpal tunnel syndrome (CTS) occurs in as many 3% of the population. This common condition should be diagnosed earlier because delays treatment can lead to loss some hand functions. Delays are caused a substantial part by patients themselves, therefore there is need have screening tool for them – especially era telemedicine. Such necessary features: easy use , simple interpret, universally available and with high sensitivity specificity values. </sec>...

10.2196/preprints.18730 preprint EN 2020-03-15
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