A5037047428- Multiple Sclerosis Research Studies
- Long-Term Effects of COVID-19
- Peripheral Neuropathies and Disorders
- Systemic Sclerosis and Related Diseases
- Genomics and Rare Diseases
- Genetics and Neurodevelopmental Disorders
- Cerebral Venous Sinus Thrombosis
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Arsenic contamination and mitigation
- Retinal and Optic Conditions
- COVID-19 Clinical Research Studies
- Rheumatoid Arthritis Research and Therapies
- Pain Mechanisms and Treatments
- Genomic variations and chromosomal abnormalities
- Venous Thromboembolism Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Silymarin and Mushroom Poisoning
- Skin and Cellular Biology Research
- Health, psychology, and well-being
- Leprosy Research and Treatment
- Cancer-related gene regulation
Qazvin University of Medical Sciences
2015-2025
Sina Hospital
2013-2025
Optic neuritis, commonly associated with multiple sclerosis (MS), can also occur in the context of hypocalcemia as a rare intriguing clinical scenario. Most recent articles have reported association papilledema and hypoparathyroidism, However, very rarely, case reports revealed hypocalcemia-induced optic neuritis well our case. We report 43-year-old woman history presenting characterized by sudden vision loss, painful eye movements, pulsatile headache. Despite normalization serum calcium...
Abstract Background Sexual dysfunction is one of the main complaints in women with Multiple Sclerosis (MS) and it affects different aspects their lives. We aimed to determine prevalence sexual among MS patients address contributing factors. Methods This cross-sectional study was performed on 100 who were referred Bu-Ali Sina Hospital 2020–2021. completed a 19-item Female Function Index (FSFI) questionnaire for each participant. also collected demographic data. Patients categorized based...
Histamine (HA) acts as a neurotransmitter in the brain, which participates regulation of many biological processes including inflammation, gastric acid secretion and neuromodulation. The enzyme histamine N-methyltransferase (HNMT) inactivates HA by transferring methyl group from S-adenosyl-l-methionine to HA, is only well-known pathway for termination neurotransmission actions mammalian central nervous system. We performed autozygosity mapping followed targeted exome sequencing identified...
The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Although the main clinical manifestations of COVID-19 infection have confined to respiratory system, there some evidence suggesting neuro-invasive potential COVID-19. There are limited reports Guillain–Barré syndrome (GBS) as peripheral nervous system complication infection. We described four patients with who developed acute polyneuropathy final diagnosis syndrome. may invade system. GBS, one critical neurological...
Intellectual disability (ID) represents a significant health challenge due to its diverse and intricate nature. A multitude of genes play role in brain development function, with defects these potentially leading ID. Considering that many have yet be identified, those identified only been found small number patients, no complete description the phenotype created by is available.
Guillain–Barré syndrome (GBS) is a neurological disorder accompanied by several signs and symptoms including progressive weakness diminished or decreased reflexes. GBS was reported as one of the complications in MERS-CoV SARS-CoV outbreaks. Several studies have complication recent COVID-19 outbreak. We report on case 55-years -old female who hospitalized with dyspnea, dry cough, myalgia. She developed Acute Motor & Sensory Axonal Neuropathy (AMSAN), rare variant muscle strength pinprick...
BackgroundRegarding the high prevalence of multiple sclerosis (MS) and COVID-19 in Iran, a multicenter study Iranian MS patients with is carried out to address concerns this population.MethodsData on from nine provinces Iran were entered web-based registry system, between July 2020 March 2021. Among symptoms, dyspnea, altered mental status, or those resulting hospital admission considered severe.ResultsA total 397 eligible identified. In addition, 310 (78%) female. The mean age was 36.5 ±...
The rising prevalence of familial multiple sclerosis (MS) in Iran has spurred interest the potential impact parental consanguinity on risk developing disease. This study aims to aggregate current knowledge and its possible effect MS risk, particularly among patients from various regions ethnicities Iran. objective is enhance understanding genetics encourage further research this field.
Evidence suggests that the relationship between arsenic metabolism and diseases, including metabolic syndrome, is complex. The aim of this study was to evaluate different types methylation its association with syndrome in an endemic area. A cross-sectional conducted on 132 subjects from Shahid-Abad Village, Qazvin province, Iran (arsenic area). Demographic characteristics, urinary species, iAs (inorganic arsenic), MMA (monomethylarsonic acid), DMA (dimethylarsinic acid) were measured for all...
Abstract Background Stroke is a widespread chronic disease which remains serious problem for public health and the cause of major disability death in adults. Despite valuable efforts, these patients still need new care programs recovery rehabilitation. Aim The aim this study to determine effect partnership model (PCM) on quality life (QOL) activities daily living (ADL) stroke participants. Method randomized clinical trial carried out an educational therapeutic center 2019. Sixty‐seven...
Approximately 1% of the global population is affected by intellectual disability (ID), and majority receive no molecular diagnosis. Previous studies have indicated high levels genetic heterogeneity, with estimates more than 2500 autosomal ID genes, which are recessive (AR). Here, we combined microarray genotyping, homozygosity-by-descent (HBD) mapping, copy number variation (CNV) analysis, whole exome sequencing (WES) to identify disease genes/mutations in 192 multiplex Pakistani Iranian...
Posterior Reversible Encephalopathy Syndrome as a Rare Presentation of Coronavirus Disease 2019: A Case Report and Literature Review
Multiple sclerosis (MS) predominantly affects women of childbearing age, significantly impacting their quality life (QOL). The diagnosis MS can influence pregnancy intention, and the level disability associated with may change before after pregnancy. This study aims to analyze reproductive characteristics Iranian female patients (PwMS) association Expanded Disability Status Scale (EDSS) tendency, providing valuable insights into disease progression development tailored treatments.
Background People living with MS confront a variety of changes and challenges that need to cope with. The aim this study was explore the coping patterns related impact on people's lives including; daily, family, social functions.Methods A constructivist grounded theory approach taken. purposive sample 16 women were recruited from clinic at teaching hospital in north Iran. Participants completed 22 semi-structured interviews. interviews digitally recorded, transcribed analyzed using initial,...
Background: Multiple sclerosis (MS) may be affected by socioeconomic status (SES). This study aims to explore the determinants of SES among Iranian patients with MS and examine how these factors relate disability disease progression. Methods: All listed in nationwide registry Iran (NMSRI) until January 8, 2022, were included this population-based study. Results: Among 5153 patients, most female (74.5%), married (70.8%), did not hold an academic degree (53.8%). Unemployment (OR: 3.75) being...