Wael M. Afifi

ORCID: 0000-0002-7388-253X
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About
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Research Areas
  • Phytochemistry and biological activities of Ficus species
  • Phytochemistry and Biological Activities
  • Phytochemistry and Bioactive Compounds
  • Natural product bioactivities and synthesis
  • Banana Cultivation and Research
  • Ancient Egypt and Archaeology
  • Natural Antidiabetic Agents Studies
  • EFL/ESL Teaching and Learning
  • Ethnobotanical and Medicinal Plants Studies
  • Bioactive Compounds and Antitumor Agents
  • Lung Cancer Treatments and Mutations
  • Moringa oleifera research and applications
  • Synthesis and biological activity
  • Nanoparticles: synthesis and applications
  • Essential Oils and Antimicrobial Activity
  • Phytochemical compounds biological activities
  • PI3K/AKT/mTOR signaling in cancer
  • Plant Pathogens and Fungal Diseases
  • Ginger and Zingiberaceae research
  • Discourse Analysis in Language Studies
  • Medicinal Plants and Neuroprotection
  • Multilingual Education and Policy

Al-Azhar University
2020-2024

Sinai University
2020-2024

Al-Azhar University
2020

Zagazig University
2003

A new series of pyrimidine-5-carbonitrile derivatives has been designed as ATP mimicking tyrosine kinase inhibitors the epidermal growth factor receptor (EGFR).

10.1039/d0ob01557a article EN Organic & Biomolecular Chemistry 2020-01-01

Fungal-derived natural products continue to play a pivotal role in the discovery of drug agents for human, veterinary, and general agricultural use. The fungus Neodidymelliopsis negundinis presents significant saprobic ascomycete whose metabolites remained hitherto unstudied. Herein we report isolation eight unprecedented secondary named neodidymelliosides A B (1 2), neodidymelliol (3), neodidymellioic acids A–E (4–8) produced by submerged cultures fungus. Compound 1 proved be most active...

10.1021/acs.jnatprod.3c01094 article EN Journal of Natural Products 2024-02-14

Abstract The green synthesis of silver nanoparticles (SNPs) using plant extracts has gained great attention due to its unique properties. So, in this study, the aqueous and n ‐hexane Lampranthus coccineus F. Aizoaceae were used for nanoparticles. early signs SNPs detected by a color change from yellow reddish‐brown color. formation was further confirmed transmission electron microscope (TEM), UV‐Visible spectroscopy, zeta potential. TEM analysis showed spherical with mean size ranges between...

10.1002/slct.202002947 article EN ChemistrySelect 2020-10-20

In our continuous study for some African plants as a source antitrypanosomally and cytotoxic active drugs, nine different belonging to the Crassulaceae family have been selected present study. Sedum sieboldii leaves extract showed an antitrypanosomal activity against Trypanosoma brucei with IC50 value of 8.5 µg/mL. addition, they activities (HCT-116), (HEPG-2) (MCF-7), values 28.18 ± 0.24, 22.05 0.66, 26.47 0.85 µg/mL, respectively. Furthermore, displayed inhibition Topoisomerase-1 1.31 It...

10.3390/molecules27248809 article EN cc-by Molecules 2022-12-12
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