Natsuko Zenimura

ORCID: 0000-0002-7393-1637
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About
Contact & Profiles
Research Areas
  • Blood Pressure and Hypertension Studies
  • Pharmaceutical Practices and Patient Outcomes
  • Heart Rate Variability and Autonomic Control
  • Hormonal Regulation and Hypertension
  • Pharmacology and Obesity Treatment
  • Sodium Intake and Health
  • Pharmacy and Medical Practices
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular Syncope and Autonomic Disorders
  • Heart rate and cardiovascular health
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiac, Anesthesia and Surgical Outcomes

Daiichi-Sankyo (Japan)
2011-2018

Japanese Society of Hypertension
2016

Daiichi Sankyo (Germany)
2011-2012

On the basis of studies that investigated relationship between baseline clinic blood pressure (CBP) or home (HBP) values and cardiovascular (CV) events, HBP has been reported to have a stronger prognostic ability. However, few compared ability on-treatment CBP HBP. The HBP, measured twice in morning at bedtime, CV events was over 20 000 patients HONEST (Home measurement with Olmesartan Naive Establish Standard Target pressure) Study, prospective, 2-year observational study treatment an...

10.1038/hr.2012.160 article EN cc-by-nc-nd Hypertension Research 2012-10-25

We investigated the prognostic significance of morning home SBP (MHSBP) and clinic (CSBP) at baseline during follow-up in on-treatment hypertensive patients.In Home blood pressure measurement with Olmesartan Naive patients to Establish Standard Target study, more than 20 000 Japanese who started treatment olmesartan were followed for cardiovascular events 2 years. MHSBP CSBP measured compared terms predicting events.The analysis included 21 591 (50.6% female; average age 64.9 years; mean...

10.1097/hjh.0000000000000966 article EN Journal of Hypertension 2016-06-15

Background: In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14.4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results use survey, which we conducted as survey. Objective: This prospective was assess β-adrenergic receptor antagonist (β-blocker) Artist® Tablets (carvedilol)...

10.2165/11592450-000000000-00000 article EN cc-by-nc Drugs in R&D 2011-06-01

The appropriate target blood pressure (BP) in elderly patients with hypertension remains uncertain. We investigated the relationship between morning home systolic (MHSBP) during follow-up and cardiovascular (CV) risk outpatients receiving olmesartan-based treatment aged <75 years (n = 16799) ≥75 4792) HONEST study. In period (mean 2.02 years), for major CV events was significantly higher MHSBP ≥155 mmHg compared <125 both age groups Cox proportional hazards model adjusted other factors there...

10.1080/10641963.2016.1267194 article EN Clinical and Experimental Hypertension 2018-03-28

In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14-4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results long-term special that we conducted as survey.The prospective was assess β-adrenergic receptor antagonist (β-blocker) Artist® tablets 10 mg, 20 mg (carvedilol)...

10.2165/11592460-000000000-00000 article EN cc-by-nc Drugs in R&D 2011-06-01

Background: In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14-4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results long-term special that we conducted as survey. Objective: The prospective was assess b-adrenergic receptor antagonist (β-blocker) Artist® tablets 10 mg,...

10.1007/bf03259807 article EN cc-by-nc Drugs in R&D 2011-06-01

Background: In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14.4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results use survey, which we conducted as survey. Objective: This prospective was assess β-adrenergic receptor antagonist (β-blocker) Artist® Tablets (carvedilol)...

10.1007/bf03259806 article EN cc-by-nc Drugs in R&D 2011-06-01

Background: The stronger prognostic ability of baseline home blood pressure (HBP) to predict future cardiovascular (CV) events has been reported. However, only few studies have compared the on-treatment HBP and clinic (CBP). Method: HONESTstudy, a prospective 2-year observational study olmesartan based treatment in hypertensive patients investigates relationship between achieved CBP measured twice morning at bedtime on 2 daysat each measurement point development CV 22,373 registered from...

10.1097/01.hjh.0000420799.82537.e5 article EN Journal of Hypertension 2012-09-01
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