- Blood Pressure and Hypertension Studies
- Pharmaceutical Practices and Patient Outcomes
- Heart Rate Variability and Autonomic Control
- Hormonal Regulation and Hypertension
- Pharmacology and Obesity Treatment
- Sodium Intake and Health
- Pharmacy and Medical Practices
- Cardiovascular Health and Disease Prevention
- Cardiovascular Syncope and Autonomic Disorders
- Heart rate and cardiovascular health
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
Daiichi-Sankyo (Japan)
2011-2018
Japanese Society of Hypertension
2016
Daiichi Sankyo (Germany)
2011-2012
On the basis of studies that investigated relationship between baseline clinic blood pressure (CBP) or home (HBP) values and cardiovascular (CV) events, HBP has been reported to have a stronger prognostic ability. However, few compared ability on-treatment CBP HBP. The HBP, measured twice in morning at bedtime, CV events was over 20 000 patients HONEST (Home measurement with Olmesartan Naive Establish Standard Target pressure) Study, prospective, 2-year observational study treatment an...
We investigated the prognostic significance of morning home SBP (MHSBP) and clinic (CSBP) at baseline during follow-up in on-treatment hypertensive patients.In Home blood pressure measurement with Olmesartan Naive patients to Establish Standard Target study, more than 20 000 Japanese who started treatment olmesartan were followed for cardiovascular events 2 years. MHSBP CSBP measured compared terms predicting events.The analysis included 21 591 (50.6% female; average age 64.9 years; mean...
Background: In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14.4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results use survey, which we conducted as survey. Objective: This prospective was assess β-adrenergic receptor antagonist (β-blocker) Artist® Tablets (carvedilol)...
The appropriate target blood pressure (BP) in elderly patients with hypertension remains uncertain. We investigated the relationship between morning home systolic (MHSBP) during follow-up and cardiovascular (CV) risk outpatients receiving olmesartan-based treatment aged <75 years (n = 16799) ≥75 4792) HONEST study. In period (mean 2.02 years), for major CV events was significantly higher MHSBP ≥155 mmHg compared <125 both age groups Cox proportional hazards model adjusted other factors there...
In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14-4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results long-term special that we conducted as survey.The prospective was assess β-adrenergic receptor antagonist (β-blocker) Artist® tablets 10 mg, 20 mg (carvedilol)...
Background: In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14-4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results long-term special that we conducted as survey. Objective: The prospective was assess b-adrenergic receptor antagonist (β-blocker) Artist® tablets 10 mg,...
Background: In Japan, when pharmaceutical companies launch a new drug, they are obligated to conduct post-marketing survey evaluate the safety and efficacy of drug in accordance with Good Post-Marketing Surveillance Practice under Article 14.4 (re-examination) Pharmaceutical Affairs Law at contracted medical institutions. We report results use survey, which we conducted as survey. Objective: This prospective was assess β-adrenergic receptor antagonist (β-blocker) Artist® Tablets (carvedilol)...
Background: The stronger prognostic ability of baseline home blood pressure (HBP) to predict future cardiovascular (CV) events has been reported. However, only few studies have compared the on-treatment HBP and clinic (CBP). Method: HONESTstudy, a prospective 2-year observational study olmesartan based treatment in hypertensive patients investigates relationship between achieved CBP measured twice morning at bedtime on 2 daysat each measurement point development CV 22,373 registered from...