A5063714614- Bone Metabolism and Diseases
- Osteoarthritis Treatment and Mechanisms
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects of Medicinal Plants
- Inflammatory mediators and NSAID effects
- Alcohol Consumption and Health Effects
- MicroRNA in disease regulation
- Connective tissue disorders research
- Lipid metabolism and disorders
- Circular RNAs in diseases
- Inflammasome and immune disorders
- Metabolomics and Mass Spectrometry Studies
- Cytokine Signaling Pathways and Interactions
- Trace Elements in Health
Changchun University of Chinese Medicine
2021-2024
Eucommia leaves are dry of ulmoides which have long been considered as a functional health food for the treatment hypertension, hypercholesterolemia, fatty liver, and osteoporosis. With recent development Chinese medicine, widely used tonifying kidneys strengthening bone. However, specific molecular mechanism bone remains largely unknown. Osteoblasts main cells formation; thus, it is essential to study effect on osteoblasts better understand their action. In present study, we prepared an...
Abstract Objective: To explore the proteomics profiles of hepatocytes mice treated with acupuncture for type 2 diabetes mellitus (T2DM) non-alcoholic fatty liver disease (NAFLD). Methods: We used a Tandem mass tag (TMT)-based quantitative approach to identify proteins potential molecular mechanisms associated interventions T2DM NAFLD. Results: Acupuncture effectively improved body weight, blood glucose, and insulin levels in NAFLD mouse models reversed steatosis within hepatocytes....
Abstract Background Deer antler is a zoological exception due to its fantastic characteristics, including amazing growth rate and repeatable regeneration. has been used as key ingredient in traditional Chinese medicine relating kidney bone health for centuries. The aim of this study was dissect the molecular regulation deer extract (DAE) on xiphoid cartilage (XC). Methods DAE experiment same one that prepared previously described. specific pathogen-free (SPF) grade Sprague-Dawley (SD) rats...
Abstract Objective: The cathepsin present in lysosomal cells may be closely related to bone, muscle & joint diseases (BMJD)including osteoporosis and osteoarthritis, but its specific mechanism of action still needs further research exploration. aim this study is use a two-sample Mendelian randomization (MR) comprehensive analysis explore the causal relationship between risk BMJD. Method: Based on published genetic data, used method causality morbidity 9 cathepsins with rheumatoid...