SUMMARY 1. A study performed > 10 years ago and case reports published recently suggest that triclabendazole is effective for the treatment of patients with fascioliasis. 2. To confirm efficacy a human formulation triclabendazole, we enrolled 165 into present divided subjects two groups: (i) those who had fascioliasis, as evidenced by presence ova in their stools; (ii) clinical laboratory data suggesting 3. Patients were randomly allocated to receive mg/kg, p.o., 1, 2 or 3 days (single‐,...

Rhabdomyolysis is a clinical and biochemical syndrome occurring when skeletal muscle cells erupt result in release of creatine phosphokinase (CPK), lactate dehydrogenase (LDH) myoglobin into the interstitial space plasma. Mechanical trauma, compression, excessive activity ischemia are frequent causes, but non-traumatic rhabdomyolysis usually caused by toxic reaction to drugs. In this study, 181 patients suspected were admitted poisoning center Loghman-Hakim Hospital Tehran during one year...

The present study intends to look into the prevalence of these infections in non-IVdrug abusing addicts whom were treated at our center. A pilot was conducted on 20 patients who admitted poisoning center Loghman-Hakim Hospital Tehran due non-IV drug overdose. One positive HIV antibody and one HBS antigen cases found this group. later expanded a descriptive cross-sectional 214 patients. In 196 (91.6%) male 18 (8.4%) female. average age subjects 37.9, having highest frequency between...

ABSTRACT Body packers are people who illegally carry drugs, mostly cocaine as well opium and/or heroin, concealed within their bodies. The packets inserted in the mouth, rectum, or vagina order to get across borders without being detected. In this presentation we report a case of an body packer and review available scientific literature by focusing on mechanisms toxicity treatment approach. patient was 35-year-old man had lethargy, respiratory depression, tachycardia, normal blood pressure,...

Background Acinetobacter baumannii (A. baumannii) has emerged globally as a significant pathogen in hospitals. It is also present soil and water. In previous study, we discovered that the A. class 2 integron occurred most frequently. Here, determined whether around our hospital, if cause for increasing numbers of infections intensive care unit (ICU) patients. Methods This cross-sectional prospective study was conducted two ICUs at Loghman-Hakim Hospital, Tehran, Iran, from November 2012 to...

ABSTRACT The clinical syndrome of rhabdomyolysis is caused by injury skeletal muscles resulting in release intracellular muscle constituents. Drug poisoning one the causes severe rhabdomyolysis. Severe electrolyte disorders and acute renal failure may occur rhabdomyolysis, leading to life-threatening situations. Early initiation replacement therapy can help improve outcome. In present retrospective study, medical records 181 patients suspected from Loghman-Hakim Hospital period 2004 2005...

Ventilator-Associated Pneumonia (VAP) is the main cause of nosocomial infection at intensive care units (ICUs), which causes high mortality and morbidity.The objective present survey was to identify VAP risk prognostic factors among poisoned patients, who were admitted toxicological ICU (TICU), especially central nervous system (CNS) depressants due their prevalence importance.A case-control study conducted Loghman Hakim hospital between March 2013 2014. Among 300 patients with mechanical...

Body temperature is a critical criterion of health. Drugs and variety poisons can affect body in poisoned patients, causing hyperthermia hyperpyrexia.Our previous study's findings patients with organophosphate led us to the goal this study: obtaining initial tympanic by toxins.A cross-sectional study reviewed records who were admitted toxicological intensive care unit (TICU) at Loghman Hakim hospital poison center (LHHPC) from February 2014 2015. The data collected included gender, age, type...

Background: Lactate level is known to increase among the majority of patients with toxicity. This study aimed determine whether lactate upon admission higher ventilator-associated pneumonia (VAP). Objectives: We serum associated increased risk VAP in intensive care unit (ICU)-admitted Methods: retrospective was conducted a training medical poisoning center Iran, using convenience sampling. A total 157 poisoned patients, aged ≥ 13 years, who were admitted ICU over past seven months, included...

Background: Early and appropriate antidotal therapy is crucial for patients with organophosphate poisoning. Objectives: Given the lack of a comprehensive consensus on optimal dose pralidoxime poisoning, this study aims to develop machine learning-based prediction model determine individualized these patients. Methods: The dataset was divided into training test sets 70:30 ratio. Feature selection conducted using Pearson’s correlation coefficient (filter approach) method. Both classification...

Vancomycin has been the first-line therapy for MRSA infection disease many years. According to standard guidelines, therapeutic vancomycin trough concentration should be above 10 mg/L and optimally between 15-20 mg/L. The aim of this study was evaluate level in patients infected with MRSA.This cross- sectional included a sample 170 admitted ICU Loghman hospital. We used questionnaire, then applied appropriate statistical tests. All collected data had analyzed interpreted by IBM SPSS...

Background: Platelet count is a readily available biomarker predicting disease severity and risk of mortality in the intensive care units (ICU). This study aims to describe frequency, assess factors, evaluate impact thrombocytopenia on patient outcomes Toxicological ICU (TICU).Methods: In this prospective observational Cohort study, we enrolled 184 patients admitted our TICU from October 1st, 2019, August 23rd, 2020. Mild/moderate severe were defined as at least one platelet counts less than...