A5012489162- Hemoglobinopathies and Related Disorders
- Acute Myeloid Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Iron Metabolism and Disorders
- Neutropenia and Cancer Infections
- Blood groups and transfusion
- Kawasaki Disease and Coronary Complications
- Migraine and Headache Studies
- Radiation Dose and Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Myeloid Leukemia Treatments
- Head and Neck Surgical Oncology
- Dental Radiography and Imaging
- Dermatological and Skeletal Disorders
- Viral Infections and Immunology Research
- Sexual function and dysfunction studies
- Digestive system and related health
- Reconstructive Surgery and Microvascular Techniques
- Neurogenetic and Muscular Disorders Research
- Hematological disorders and diagnostics
- Immunodeficiency and Autoimmune Disorders
- Craniofacial Disorders and Treatments
- Ear and Head Tumors
- Child Nutrition and Water Access
- Respiratory viral infections research
Bristol-Myers Squibb (United States)
2021-2024
Necmettin Erbakan University
2016-2024
Novartis (United States)
2023
Predictive Science (United States)
2023
Konya Food and Agriculture University
2022
Amgen (United States)
2018-2021
Mersin Üniversitesi
2016
Afyon Kocatepe University
2005-2015
Hitit Üniversitesi
2015
Istanbul University
1996
Among the difficulties of living with β-thalassemia, patients frequently require blood transfusions and experience iron overload. As serum ferritin (SF) provides an indication potential overload, we conducted a systematic literature review (SLR) to assess whether SF levels are associated clinical economic burden patient-reported outcomes (PROs). The SLR was on 23 April 2020 followed by analysis literature. Dual-screening performed at title, abstract, full-text using predefined inclusion...
Abstract Background Patients with transfusion‐dependent (TD) β‐thalassemia require long‐term red blood cell transfusions (RBCTs) that lead to iron overload, impacting health‐related quality of life (HRQoL). Methods The impact luspatercept, a first‐in‐class erythroid maturation agent, versus placebo on HRQoL patients TD was evaluated in the phase 3 BELIEVE trial. assessed at baseline and every 12 weeks using 36‐item Short Form Health Survey (SF‐36) Transfusion‐dependent Quality Life...
Introduction Malnutrition is defined as a pathological condition arising from deficient or imbalanced intake of nutritional elements. Factors such increasing metabolic demands during the disease course in hospitalized patients and inadequate calorie increase risk malnutrition. The aim present study to evaluate status admitted pediatric intensive care units (PICU) Turkey, examine effect nutrition on treatment process draw attention need for regulating support while continuing existing...
Background and Objective: Malnutrition is a major complication of inflammatory bowel disease (IBD). Our aim the study was to examine effects Modulen IBD supplementation, which administered patients without limiting their daily diet in addition medical treatment, on clinical, laboratory, anthropometric values, activities these patients. Materials Methods: Seventy three children with were evaluated retrospectively. The cases classified as those who had Crohn receiving (CD-M; n = 16) or not...
Objectives The non-transfusion-dependent beta-thalassaemia-patient-reported outcome (NTDT-PRO) questionnaire was developed for assessing anaemia-related tiredness/weakness (T/W) and shortness of breath (SoB) among patients with NTDT. Psychometric properties were evaluated using blinded data from the BEYOND trial ( NCT03342404 ). Design Analysis a phase 2, double-blind, randomised, placebo-controlled trial. Setting USA, Greece, Italy, Lebanon, Thailand UK. Participants Adults (≥18 years)...
We describe CT scans of a case with bilateral aplasia frontal and sphenoid sinuses symmetrical hypoplasia the ethmoid cellules maxillary sinuses. This appears to be first in English-language literature these combined findings.
This study aims to evaluate the analysis and publication rates of abstracts presented at Turkish National Radiology meetings in 2010-2012.Abstracts national radiology 2010, 2011, 2012 were included study. The presentations classified according presentation type (oral or poster presentations), type, design, imaged organ body systems, imaging modalities, time interval between date, journal which article was published. conversion rate into full-text articles peer-reviewed journals surveyed...
Anemia is the most common form of cytopenia in patients with myelodysplastic syndromes (MDS), who require chronic red blood cell transfusions and may present high serum ferritin (SF) levels as a result iron overload. To better understand potential effects SF levels, we conducted systematic literature review (SLR) to identify evidence on relationship between clinical, economic, or humanistic outcomes adult MDS. Of 267 references identified, 21 were included. No studies assessing their...
An adipofascial flap distally based on the first dorsal metatarsal artery is described. This was used successfully in three cases with skin defects of distal foot. The advantages this are minimal donor site morbidity and its applicability for larger defects. surgical technique described, indications, advantages, disadvantages method discussed compared fasciocutaneous flap. reverse offers a new solution reconstruction foot
A patient with Klippel-Feil syndrome reported a pneumatocyst of the proximal epiphysis right cervical rib. There was no additional skeletal abnormality except for fusion C3 and C4 vertebral bodies. To best our knowledge, this is first instance particular association.
Mistaken ingestion of all manner toxic matter is common in childhood, but poisoning with fireworks and matchsticks rare. Fireworks usually contain 10% yellow phosphorus 50% potassium chlorate. Potassium chlorate an extremely reactive agent that used matchstick heads.Eleven cases (7 females 5 males; median age, 36 months [ranging from 24 to 48 months]) after matchstick(s), between February 2008 June 2014, were reviewed.The most initial symptom was vomiting except for 2 this group. Biochemical...
Abstract Background Several options for granulocyte colony-stimulating factor (G-CSF) prophylaxis of chemotherapy-induced febrile neutropenia are available to patients worldwide. We have developed a novel patient-reported outcome measure, the Satisfaction and Experience Questionnaire G-CSF (SEQ-G-CSF), help understand patients’ perspectives satisfaction with different options. Results Three oncology nurses 40 adult in United States were enrolled participated focus group discussions develop...
Sildenafil stimulates the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway through inhibition of type 5 phosphodiesterase. NO-cGMP causes smooth muscle relaxation. The aim this study is to evaluate effects sildenafil on gallbladder motility.Twenty healthy male volunteers (21-35 years old) participated in randomized, double blind, crossover, and placebo-controlled study. Oral (50 mg) or placebo was randomly dispensed each volunteer two consecutive days. After placebo, a special...
<i>Introduction:</i> We aimed to determine hemodynamic alterations in renal arteries that may have resulted from oral intake of sildenafil citrate healthy volunteers. <i>Materials and Methods:</i> Twelve volunteers were included our study. Renal Doppler ultrasonography (US) was performed before the drug assess basal values. Maximum peak systolic velocity, resistivity pulsatility indices measured segmental branches both all ex- aminations. After measurements 50 mg or...
This study aimed to evaluate the nutritional status and body composition in children with cystic fibrosis (CF), accordance new targets defined by European Society for Clinical Nutrition Metabolism (ESPEN), Paediatric Gastroenterology, Hepatology (ESPGHAN) Cystic Fibrosis (ECFS) 2016.In this cross-sectional study, data were collected prospectively a single centre. A record was made total of 95 patients CF clinical data. Anthropometric evaluated using World Health Organization growth...
Erythropoiesis-stimulating agents (ESAs) are the first-line treatment option for anemia in patients with lower-risk myelodysplastic syndromes (LR-MDS). A systematic literature review was conducted to identify evidence of association between prognostic factors and ESA response/failure LR-MDS. MEDLINE, Embase, relevant conferences were searched systematically studies assessing adult patients. Of 1566 citations identified, 38 included. Patient risk status published from 2000 onwards commonly...