Л. С. Кузнецова

ORCID: 0000-0002-7447-7245
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Research Areas
  • Immune Response and Inflammation
  • Sepsis Diagnosis and Treatment
  • Pharmacological Effects of Natural Compounds
  • Renal and related cancers
  • Bone fractures and treatments
  • Renal cell carcinoma treatment
  • Monoclonal and Polyclonal Antibodies Research
  • Medical and Biological Sciences
  • Fungal Biology and Applications
  • Sympathectomy and Hyperhidrosis Treatments
  • Acute Kidney Injury Research
  • Vitamin C and Antioxidants Research
  • Anesthesia and Neurotoxicity Research
  • Immune responses and vaccinations
  • Neurological Disorders and Treatments
  • Seaweed-derived Bioactive Compounds
  • Lipid metabolism and disorders
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Food Industry and Aquatic Biology
  • Multiple and Secondary Primary Cancers
  • Medicinal plant effects and applications
  • Tuberous Sclerosis Complex Research
  • Bone Metabolism and Diseases
  • Multiple Myeloma Research and Treatments
  • Neutropenia and Cancer Infections

Izobraževalni Center Piramida Maribor
2022

Ministry of Health of the Russian Federation
2017-2018

Russian Cancer Research Center NN Blokhin
2006-2017

Russian Academy of Sciences
2008-2011

Academy of Medical Sciences
2011

Moscow State University
2009

Lomonosov Moscow State University
2009

Aim : to evaluate results of partial nephrectomy for patients with a solitary kidney performed at the N.N. Blokhin Cancer Center. Materials and methods medical data 131 tumors underwent Department Urology Russian Research Center from 1980 2015 were collected. Median age was 57 (26–75) years, maleto-female ratio 1:1.2. RENAL score 7.0 ± 2.4. In all cases, chronic disease initially diagnosed (stage III – 30 (22.9 %), stage IV–V 0 (0 %)). follow-up 55 (6–386) months. Results . The rate...

10.17650/1726-9776-2017-13-2-27-35 article EN Cancer Urology 2017-01-01

The results of lipopolysaccharide (LPS) sorption using selective LPS adsorber (Alteco) in 20 patients with gram-negative sepsis were investigated. From 2 to 6 hemoperfusion operations performed. Concentrations interleukins (IL): IL-6, IL-8, IL-10, IL-18, serum before and after the procedure, washouts from sorbents controlled. Decrease was accompanied by improvement or normalization clinical laboratory parameters, more pronounced group survivors. High capacity LPS-adsorber its efficiency...

10.21320/1818-474x-2018-3-46-52 article EN cc-by-nc-sa Annals of critical care 2018-09-25

Objective : to assess the early and late functional results of partial nephrectomy in patients with solitary functioning kidney tumors. Materials methods . Medical data 131 consecutive parenchymal tumor, who had undergone at N. Blokhin Russian Cancer Research Center, were analyzed. The median age was 57 (26–75) years. All diagnosed tumor (median RENAL score 7.0 ± 2.4 PADUA 9.0 2.2). baseline glomerular filtration rate (GFR) 74 (33–159) ml/min/1.73 m2 (30 (22.9 %) – stage III chronic disease...

10.17650/1726-9776-2017-13-3-46-53 article EN Cancer Urology 2017-01-01

Sepsis is one of the most often met complications for cancer patients. It caused by immunosuppression after radiotherapies and chemotherapies as extensive operations. For sepsis treatment, many experts now recommend even more using extracorporeal detoxification methods. Since Gram-negative microorganisms in clinical hospitals, lipopolysaccharide (LPS) adsorption was offered treatment

10.1186/cc8641 article EN cc-by Critical Care 2010-01-01

Objective To examine the effects of short-term cyclic stretch on apoptosis in alveolar type II cells (A549).To study vitro direct influence mechanical stretch.Methods A549 were treated with different doses lipopolysaccharide (LPS), 0 ng/ml, 1 10 100 1000 and then lengthened 5%, 15%, 30% using a FLEXCELL tension unit 4000, vacuum-driven device that applies strain to cells, which cultured six-well plates coated collagen-I, 12 cycles/min for 4 hours.Apoptosis was measured flow cytometry method...

10.1186/cc4633 article EN cc-by Critical Care 2006-01-01
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