A5051023567- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Polymer Surface Interaction Studies
- Tribology and Wear Analysis
- Osteoarthritis Treatment and Mechanisms
- biodegradable polymer synthesis and properties
- Bone Tissue Engineering Materials
- Surgical Sutures and Adhesives
- Diamond and Carbon-based Materials Research
- Musculoskeletal pain and rehabilitation
- Robot Manipulation and Learning
- Orthopedic Surgery and Rehabilitation
- Bone and Joint Diseases
- Lubricants and Their Additives
- Tendon Structure and Treatment
- Advanced Polymer Synthesis and Characterization
- Electrospun Nanofibers in Biomedical Applications
- Hand Gesture Recognition Systems
- Connective tissue disorders research
- Mesenchymal stem cell research
- Graphene and Nanomaterials Applications
- Advanced materials and composites
- Marine Biology and Environmental Chemistry
The University of Tokyo
2014-2023
Smith College
2018
Syracuse University
2018
University of Memphis
2018
Texas A&M University
2018
John Wiley & Sons (United States)
2018
Louisiana State University Health Sciences Center New Orleans
2018
Kyocera (Japan)
2018
University of Tokyo Hospital
1999-2014
University of Gothenburg
2008
The Journal of Orthopaedic Research, a publication the Research Society (ORS), is forum for rapid high quality reports new information on full spectrum orthopaedic research, including life sciences, engineering, translational, and clinical studies.
We developed a cross-linked polyethylene (CLPE) modified with phospholipid polymer in order to address the serious problem of osteolysis caused by wear particles derived from components artificial hip joints. Our goal preventing aseptic loosening could be achieved avoiding any formation CLPE or suppressing activation cell systems particles. investigated surface and resistance properties 2-methacryloyloxyethyl phosphorylcholine (MPC) grafted onto (CLPE-g-MPC). The relative density MPC chains...
Surface modification is important for the improvement in medical device materials. 2-Methacryloyloxyethyl phosphorylcholine (MPC) polymers have attracted considerable attention as surface modifiable several devices. In this study, we hypothesize that structure of layers might affect long-term stability, hydration kinetics, wear resistance, and so forth, devices such artificial joints, poly(MPC) (PMPC) grafted assure performance Therefore, investigate properties various modifications by using...
Peritendinous adhesions are serious complications after surgical repair of tendons. As an anti-adhesion material, we focused on 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer, our original biocompatible and prepared aqueous solution MPC-containing polymer called poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate-co-p-vinylphenylboronic acid) (PMBV), which can be formed into hydrogel properties by mixture with another poly(vinyl alcohol) (PVA). The objective the...
In natural synovial joints under physiologic conditions, fluid thin-film lubrication by a hydrated layer of the cartilage is essential for smooth motion joints. The considerably less efficient artificial polyethylene prone to wear, leading osteolysis and aseptic loosening limiting longevity THA. A nanometer-scale poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) with cartilage-mimicking brushlike structures on crosslinked (CLPE) surface may provide hydrophilicity lubricity resembling...
Abstract Photo‐induced graft polymerization of 2‐methacryloyloxyethyl phosphorylcholine (MPC) on cross‐linked polyethylene (CLPE) has been developed as a novel technology for reducing wear orthopaedic bearings. In this study, the effect MPC concentration and resultant properties grafted poly layer have investigated. The thickness increased with in feed. hip simulator test confirmed that CLPE‐ g ‐MPC cups exhibited minimal compared untreated CLPE cups. Since is highly hydrophilic...
Abstract Aseptic loosening of the artificial hip joint with osteolysis due to wear particles from polyethylene cup has remained as a serious issue. To reduce this and develop novel system, we produced superlubricious metal‐bearing material: for this, grafted 2‐methacryloyloxyethyl phosphorylcholine (MPC) polymer onto surface cobalt–chromium–molybdenum (Co‐Cr‐Mo) alloy. For ensuring long‐term benefit retention poly(MPC) on Co‐Cr‐Mo alloy application several issues must be considered: strong...
In spinal surgery, a surgeon often needs to remove some parts of the spine relieve pressure on cord or other nerves. this procedure, cut and drill holes in spine. This operation is very risky because there are nerves beneath target bones, procedure therefore requires skilled experienced surgeon. However, if cutting tool could detect penetration bone autonomously, safety would be improved drastically. study presents hand-held system that detects workpiece. The learns states motion from...
Abstract Background While fear of movement is an important predictor pain and disability in osteoarthritis (OA), its impact on patients with hip OA remains uncertain. This study aimed to determine whether movement, evaluated by the Tampa Scale for Kinesiophobia (TSK)-11, catastrophizing, Pain Catastrophizing (PCS), were associated quality life (QOL) OA. Methods cross-sectional was conducted between November 2017 December 2018. Ninety-one consecutively enrolled severe scheduled primary...
Aseptic loosening induced by wear particles from the polyethylene liner is likely most common cause of long-term total hip arthroplasty failure. We developed a novel with surface graft biocompatible phospholipid polymer, 2-methacryloyloxyethyl phosphorylcholine (MPC), and previously reported grafting decreased short-term production subsequent bone resorptive responses. For clinical application, we investigated stability during sterilization resistance sterilized longer loading comparable to...