- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Analysis
- Multicomponent Synthesis of Heterocycles
- Force Microscopy Techniques and Applications
- Advanced MEMS and NEMS Technologies
- Semiconductor materials and devices
- Advancements in Semiconductor Devices and Circuit Design
- Mechanical and Optical Resonators
- Protein purification and stability
- Nanowire Synthesis and Applications
- Chemical Synthesis and Reactions
- Monoclonal and Polyclonal Antibodies Research
- Viral Infectious Diseases and Gene Expression in Insects
- Synthesis and biological activity
- Electrochemical Analysis and Applications
- Crystallography and molecular interactions
- Asymmetric Hydrogenation and Catalysis
- Carbohydrate Chemistry and Synthesis
- Microbial Natural Products and Biosynthesis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Click Chemistry and Applications
- Ferroelectric and Negative Capacitance Devices
Academy of Scientific and Innovative Research
2022-2024
National Chemical Laboratory
2022-2024
University of Bristol
2013-2022
University of Southampton
1999-2022
Lancaster University
2022
Japan Advanced Institute of Science and Technology
2022
University of Calcutta
2009-2014
Newcastle University
2009-2012
Emerging applications such as the Internet-of-Things and more-electric aircraft require electronics with integrated data storage that can operate in extreme temperatures high energy efficiency. As transistor leakage current increases temperature, nanoelectromechanical relays have emerged a promising alternative. However, reliable scalable non-volatile relay retains its state when powered off has not been demonstrated. Part of challenge is electromechanical pull-in instability, causing beam...
B. J. Egner, S. Rana, H. Smith, N. Bouloc, G. Frey, W. Brocklesby and M. Bradley, Chem. Commun., 1997, 735 DOI: 10.1039/A608521K
Abstract Aminoalkylnaphthols possess several biological and catalytic activities. A methodology has been developed for the multicomponent one-pot synthesis of aminoalkylnaphthols in dichloromethane under catalyst-free conditions at room temperature. The present approach possesses advantages such as excellent yields, quick reaction time, mild conditions, very easy purification processes. Thirteen new compounds addition to six known have synthesized by this methodology.
Digital circuits based on nanoelectromechanical (NEM) relays hold out the potential of providing an energy efficiency unachievable by conventional CMOS technology. This paper presents a detailed analysis operating characteristics fabricated curved cantilever NEM using comprehensive physical model. The mode distribution within electrical and mechanical operational domains relay is described in detail saving achievable technique body-biasing quantified. further reveals that latency can be much...
A range of PS-DVB resins were prepared by suspension polymerization with styrene, p-chloromethyl and DVB. Yields increased (from 40% to almost 80%) increasing cross-linking. The beads exhibited the expected swelling characteristics, 0.3% resin 9 times its dry volume in CHCl3. Kinetics cleavage dye Methyl Red from Rink linked showed rate enhancements up 500% between 6.0 cross-linked resins. Total synthesis Kawaguchipeptin B was carried out on resins, their performance during syntheses...
The energy consumption of field-programmable gate arrays (FPGA) is dominated by leakage currents and dynamic associated with programmable interconnect. An FPGA built entirely from nanoelectromechanical (NEM) relays can effectively eliminate losses, reduce the interconnect energy, operate at temperatures >225 °C tolerate radiation doses in excess 100 Mrad, while hybrid FPGAs comprising both complementary metal-oxide-semiconductor (CMOS) transistors NEM (NEM-CMOS) have potential to realize...
Nowadays, electronics face a challenge regarding the power consumption of integrated circuits (ICs). There is need for new devices that can provide improved switching capabilities. The downscaled electrostatically actuated ohmic switch, as (re)emerging device, promising candidate to meet this need. To bring such device seamlessly into IC design, it must be accompanied by an accurate, fast and robust analytical compact model. development main characteristics model are described within paper....
A simple, straightforward and versatile multicomponent synthetic protocol for indeno-fused heterocycles, namely diindeno[1,2-b:2′,1′-e]pyridine, indeno[1,2-b]quinoline indeno[1,2-b]cyclopenta[e]pyridine derivatives, has been developed. The strategy involves the one pot three component reaction of enaminone, dialkyl but-2-ynedioate 1,3-indanedione catalysed by FeCl3 in acetonitrile under reflux. presence rotamers products with 2- 3-substituted anilines as amine adds some interesting features...
In vitro protein refolding is one of the critical unit operations in manufacturing recombinant peptides expressed using Escherichia coli as host cells. This study focused on designing size exclusion chromatography-assisted process for biosimilar parathyroid hormone. Inclusion bodies (IBs) hormone were solubilized at higher pH, and was performed chromatography. first part investigation, DoE-based empirical optimization to achieve a yield The effect inclusion body (IB) feed volume,...
An atom-economic methodology has been developed for the multi-component one-pot synthesis of (quinolinyl-and isoquinolinyl-amino) alkyl naphthols and their bis-analogs employing ionic liquid {[ sec bmim] + Br¯} as a "dual reagent catalysis" at 25 ºC.The present approach possesses several advantages such excellent yields, lower reaction times, mild conditions, recyclability very easy purification processes.The further extended towards facile naphthoxazines in good yields formaldehyde place...
A reduced-order model for NEM relays is presented that combines electro-mechanical beam actuation and landing of tip on the surface electrode. This shows a deviation less than 2%, DC as well transient response in circuit simulation, when compared to finite-element simulation. It also an excellent match energy. The allows accurate simulation aid NEM-relay based logic design, facilitates quantification key gate-level metrics.
Diverse areas such as the Internet of Things (IoT), aerospace and industrial electronics increasingly require non-volatile memory to work under high-temperature, radiationhard conditions, with zero standby power.Nanoelectromechanical (NEM) relays uniquely have potential at 300 • C absorb high levels radiation, leakage current across entire operational range.While NEM that utilise stiction for operation been demonstrated, it is not clear how design a relay reliably achieve given programming...
Abstract It has been reported that the introduction of a dielectric barrier between adjacent digits an interdigitated electrode array can improve sensitivity as electrochemical impedance biosensor. Here we present in‐depth analysis in planar electrodes and 3‐D (with barriers). The indicates geometry not only provides lower but also higher change result molecular immobilization on surface.