A5051181638- Moringa oleifera research and applications
- Bioactive Compounds and Antitumor Agents
- Inflammation biomarkers and pathways
- Apelin-related biomedical research
- MicroRNA in disease regulation
- Glutathione Transferases and Polymorphisms
- IL-33, ST2, and ILC Pathways
- Immune Cell Function and Interaction
- Adipokines, Inflammation, and Metabolic Diseases
- Hydrogen's biological and therapeutic effects
- Genomics, phytochemicals, and oxidative stress
- Cancer, Stress, Anesthesia, and Immune Response
- Ginger and Zingiberaceae research
- Healthcare Quality and Satisfaction
- Effects of Radiation Exposure
- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Chemokine receptors and signaling
- Cancer Immunotherapy and Biomarkers
- Cell Adhesion Molecules Research
- Phytochemistry and biological activity of medicinal plants
- Traditional and Medicinal Uses of Annonaceae
- Mangiferin and Mango Extracts
- Diverse Scientific Research Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Naresuan University
2017-2024
Maharat Nakhon Ratchasima Hospital
2023-2024
University of Southampton
2020-2022
Naresuan University Hospital
2022
Ryhov Hospital Jönköping
2017-2019
Linköping University
2017
Moringa oleifera (MO) is an important plant for traditional medicine. The present study aimed to identify the MO active phytochemical compounds their ability against inflamed macrophages. An ethyl acetate extract fraction of was fractionation by flash column chromatography. Human macrophages were stimulated Lipopolysaccharide and then treated with fractions examine anti-inflammatory activity cellular mechanism. analyzed liquid chromatography electrospray ionization quadrupole time-of-flight...
Summary Cigarette smoke contains toxic and carcinogenic substances that contribute to the development of cancer various diseases. Genetic variation might be important, because not all smokers develop smoking‐related disease. The current study addressed possible interactions among selected single nucleotide polymorphisms ( SNP s) in genes related systemic inflammation, smoking status, levels circulating immune response cells plasma biomarkers inflammation. Sixty‐four healthy blood donors were...
Squamous cell carcinoma is the most common type of head and neck cancer worldwide. Radiation chemotherapy are general treatments for patients; however, these remedies can have adverse side effects tumours develop drug resistance. Effective still require improvement patients. Here, we investigated anti-cancer effect Moringa oleifera (MO) Lam. leaf extracts their fractions, 3-hydroxy-β-ionone on SCC15 line. were treated with without MO fractions. MTT assay was used to determine viability...
This research characterizes phytochemicals inherent in lotus flower and investigates the antioxidant immunomodulatory activity of ethyl acetate (EA) alcohol (ET) petal extracts. In experiment, human monocytes-derived macrophages were stimulated by lipopoly-saccharide to mimic bacteria-induced inflammation. The results showed that ferulic acid, couma-rin, chlorogenic acid three dominant polyphenols. EA ET extracts also possessed high capability. Furthermore, exhibited properties suppressing...
Smokers have high plaque accumulation that initiates gingival inflammation and progresses to periodontitis. Thus, oral hygiene control microbial formation is an effective method of preventing gingivitis. Medicinal plants such as Moringa oleifera Lam. (MO) Cyanthillium cinereum (Less.) H. Rob. (CC) anti-inflammatory effect might improve health in smokers. This study evaluated the MO leaf CC extracts using lozenges a combination + on gingivitis volunteer Lozenges consisting were developed...
Independently of tumour and treatment modulation, the host immune response status plays an important role in clinical outcome patients with cancer. The influence single nucleotide polymorphisms (SNPs) adjuvant radiotherapy (RT) on systemic breast cancer was investigated. Materials Methods: Eighty-six female recovering from surgery were As a control cohort, 82 healthy blood donors used. Blood-based SNPs, plasma C-reactive protein (CRP), cytokines chemokines analyzed for this purpose. Results:...
Chronic inflammatory conditions lead to the generation of excessive reactive oxygen species which can give rise T cell hyporesponsiveness.Thus there has been an interest target these mediators with nutrients have anti-oxidant properties.Accordingly Moringa oleifera extract reported anti-inflammatory and properties.We now examined effects Lam. on depressed human T-cell responses, (IL-2 IL-2 mRNA production) DNA damage (quantifying oxidized derivative deoxyguanosine, 8-OHdG) induced oxidative...
Adjuvant radiotherapy (RT) damages multiple layers of skin, muscle, blood vessels and cells that are included within the RT area. Indirect, bystander systemic effects could also develop in not directly hit by radiation.Ninety-three female patients recovering from breast cancer surgery 82 healthy donors were analyzed. For identification adaptive innate immune response, rapid low-cost blood-based biomarkers assayed.Post-operated had a decreased number circulating response but increased...
Moringa leaves provide numerous health benefits due to their anti-inflammatory properties. This study presents the first evidence that endothelial cell inflammation can potentially be ameliorated by moringa leaf extract. Here, we established an experimental human blood vessel model of using EA.hy926 cells. TNF-α was added after pre-treating cells with crude extract from oleifera Lam., a constituent fraction extract, and bioactive component 3-hydroxy-β-ionone. The active ingredient...
Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide. Late-stage patients have a significant chance of local recurrence distant metastasis, as well poor prognosis. Therapeutic goals for must be improved personalized to reduce adverse effects. This study explored anti-proliferative activity immunomodulation potential constituents crude kaffir lime leaf extract (lupeol, citronellal citronellol) under co-culture. Results showed high cytotoxicity human SCC15...
Abstract Endothelial cells maintain blood fluidity, control regional flow and contribute to regulation of pressure, inflammation clotting. The purpose this study was investigate into the effects a bioactive compound from moringa leaf on endothelial cell production inflammatory mediators monocyte adhesion transmigration. EA.hy926 were pre-treated with crude Moringa oleifera Lam. extract, constituent fraction 6 extract component 3-HBI followed by stimulation TNF-α. incubated or...