George Lazaridis

ORCID: 0000-0002-7476-2513
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About
Contact & Profiles
Research Areas
  • Pleural and Pulmonary Diseases
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Lung Cancer Treatments and Mutations
  • Retinal Diseases and Treatments
  • Trauma Management and Diagnosis
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Optical Coherence Tomography Applications
  • Respiratory Support and Mechanisms
  • Congenital Diaphragmatic Hernia Studies
  • Software-Defined Networks and 5G
  • Cancer Diagnosis and Treatment
  • Advances in Oncology and Radiotherapy
  • Neuroendocrine Tumor Research Advances
  • Neuroblastoma Research and Treatments
  • Network Security and Intrusion Detection
  • Tumors and Oncological Cases
  • Airway Management and Intubation Techniques
  • Cancer Treatment and Pharmacology
  • HER2/EGFR in Cancer Research
  • Health and Medical Research Impacts
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Smart Grid Security and Resilience

Aristotle University of Thessaloniki
2012-2024

Papageorgiou General Hospital
2004-2024

Information Technologies Institute
2021-2024

Hella (Germany)
2024

University College London
2019-2023

Moorfields Eye Hospital NHS Foundation Trust
2019-2023

City, University of London
2023

International Hellenic University
2021-2023

Guy's Hospital
2021

King's College London
2020-2021

LTX-315 is a first-in-class, 9-mer membranolytic peptide that has shown potent immunomodulatory properties in preclinical models. We conducted phase I dose-escalating study of intratumoral administration patients with advanced solid tumors.Thirty-nine were enrolled, receiving injections into accessible tumors. The primary objective was to assess the safety and tolerability this approach, antitumor activity as secondary objectives. Tumor biopsies collected at baseline posttreatment for...

10.1158/1078-0432.ccr-20-3435 article EN Clinical Cancer Research 2021-02-04

A chest tube is a flexible plastic that inserted through the wall and into pleural space or mediastinum. It used to remove air in case of pneumothorax fluid such as effusion, blood, chyle, pus when empyema occurs from intrathoracic space. also known Bülau drain an intercostal catheter. Insertion tubes widely performed by radiologists, pulmonary physicians thoracic surgeons. Large catheters small are based on each situation medical doctor encounters. In current review we will focus systems use.

10.3978/j.issn.2305-5839.2015.02.09 article EN PubMed 2015-03-01

A pacemaker (PM) (or artificial PM, so as not to be confused with the heart's natural PM) is a medical device that uses electrical impulses, delivered by electrodes contracting heart muscles, regulate beating of heart. The primary purpose this maintain an adequate rate, either because PM fast enough, or there block in conduction system. Modern PMs are externally programmable and allow cardiologist select optimum pacing modes for individual patients. Some combine defibrillator single...

10.3978/j.issn.2305-5839.2015.02.06 article EN PubMed 2015-03-01

Paclitaxel-based regimens are frequently associated with the development of peripheral neuropathy. The autonomous nervous system (ANS) effects, however, this chemotherapeutic agent remain unexplored.We investigated a group 31 female patients ovarian cancer receiving treatment paclitaxel and carboplatin, as well 16 healthy age- gender-matched volunteers. All study participants completed questionnaire were assessed neurophysiologically at three time points (baseline, 3-4 months 6-8 following...

10.1186/s12883-016-0710-4 article EN cc-by BMC Neurology 2016-09-30

This paper presents a new algorithm which can be used to register images of the same or different modalities, e.g., with multiple channels, such as X-rays, temperature elevation, simply spectral bands. In particular, correlation-based scheme is used, but instead gray values, it correlates numbers formulated by combinations extracted local Walsh coefficients images. Each image patch expanded in terms basis functions. function thought measuring aspect structure, horizontal edge, corner, etc....

10.1109/tip.2006.877346 article EN IEEE Transactions on Image Processing 2006-07-21

Non-small cell lung cancer (NSCLC) represents 85% of all cancers. It is estimated that 60% patients with NSCLC at time diagnosis have advanced disease. The aim this study was to investigate clinical and demographic prognostic factors long term survival in unresectable NSCLC.We retrospectively reviewed data 1,156 stage IIIB or IV who survived more than 60 days from the treated August 1987 until March 2013 Oncology Department Pulmonary Clinic General Hospital Papanikolaou. Initially univariate...

10.21037/atm.2016.05.13 article EN Annals of Translational Medicine 2016-05-01

Non-small cell lung cancer, even when diagnosed in early stages, has been linked with poor survival rates and distant recurrence patterns. Novel therapeutic approaches harnessing the immune system have implemented following designated steps of advanced NSCLC treatment strategies. Immune-checkpoint inhibitor (ICI) regimens as monotherapy, combinational, or alongside chemotherapy intensely investigated adjuvant, neoadjuvant, and, more recently, perioperative strategies, representing pivotal...

10.3390/cancers16091619 article EN Cancers 2024-04-23

Background: Trastuzumab is a monoclonal antibody against HER2-positive breast cancer. Despite improving the natural history of disease, there number patients who are resistant to it, whereas all will eventually develop resistance and disease progress. Inconsistent preclinical data show that IGF-R pathway may contribute either de novo or acquired trastuzumab. Materials Methods: In total, 227 trastuzumab-treated metastatic cancer were evaluated for IGF-1, IGF-1R, GLP-1R, Akt1, Akt2 Akt3 mRNA...

10.21873/cgp.20105 article EN Cancer Genomics & Proteomics 2018-01-01

Novel therapies for lung cancer are being explored nowadays with local the tip of arrow. Intratumoral chemotherapy administration and microwave ablation have been investigated in several studies. It has previously proposed that lipiodol ability to modify microenvironment matrix. In our current study we this theory BALBC mice. total 160 mice were divided eight groups: a) control, b) cisplatin, c) microwave, d) lipiodol, e) cisplatin f) g) h) microwave. Lewis carcinoma cell lines (10(6))...

10.7150/jca.10970 article EN cc-by-nc Journal of Cancer 2015-01-01
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