- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sleep and related disorders
- Pulmonary Hypertension Research and Treatments
- Lung Cancer Treatments and Mutations
- Sleep and Wakefulness Research
- Respiratory Support and Mechanisms
- Lung Cancer Research Studies
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Airway Management and Intubation Techniques
- Asthma and respiratory diseases
- Nitric Oxide and Endothelin Effects
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiovascular Disease and Adiposity
- Pneumonia and Respiratory Infections
- Parathyroid Disorders and Treatments
- Pleural and Pulmonary Diseases
- Medical Imaging and Pathology Studies
- Cancer Immunotherapy and Biomarkers
- Respiratory viral infections research
- Systemic Sclerosis and Related Diseases
- Lung Cancer Diagnosis and Treatment
National and Kapodistrian University of Athens
2016-2025
Evangelismos Hospital
2025
Alexandra Hospital
2015-2024
Therapeutics Clinical Research
2024
Sahlgrenska University Hospital
2023
Turku University Hospital
2022
Vilnius University
2022
Saratov State University
2022
University of Turku
2022
Inserm
2022
The proinflammatory cytokines, TNFα and IL-6, are elevated in obstructive sleep apnea (OSA) have been proposed as mediators of excessive daytime sleepiness humans. We tested the effects etanercept, a medication that neutralizes is approved by FDA for treatment rheumatoid arthritis, eight obese male apneics. These patients participated pilot, placebo-controlled, double-blind study during which nighttime polysomnography, multiple latency test, fasting blood glucose plasma levels C-reactive...
The aim of this study was to determine if the lockdown measures applied due pandemic Coronavirus Disease 2019 (COVID-19) affected sleep general population and health professionals in six different countries (Greece, Switzerland, Austria, Germany, France, Brazil). We used a web-based survey with short questionnaire 13 questions, translated into four languages (Greek, German, French, Portuguese). included information about demographic professional data, quantitative qualitative characteristics...
Excessive daytime sleepiness (EDS) is a symptom of obstructive sleep apnea (OSA) that resolves under treatment with continuous positive airway pressure (CPAP). In some patients, persists despite CPAP treatment. We retrospectively analyzed data on subjective residual EDS, assessed as an Epworth Sleepiness Scale score (ESS) >10, in patients from the European Sleep Apnea Database ( n = 4,853, mean age ± SD 54.8 11.8 years, 26.1% females), at baseline and first visit (median follow-up: 5...
The central venous catheter (CVC) is a placed into large vein in the neck [internal jugular (IJV)], chest (subclavian or axillary vein) groin (femoral vein). There are several situations that require insertion of CVC mainly to administer medications fluids, obtain blood tests (specifically "central oxygen saturation"), and measure pressure. usually remain place for longer period time than other access devices. according drug administration length stay specific systems indicated such as;...
Aim The impact of obstructive sleep apnoea (OSA)–COPD overlap syndrome (OVS) on quality and cardiovascular outcomes has not been fully explored. We aimed to compare clinical polysomnographic characteristics patients with OVS versus OSA, explore pathophysiological links between comorbidities. Study design methods This cross-sectional analysis initially included data from 5600 OSA lung function in the European Sleep Apnoea Database. Two subgroups (n=1018) or (n=509) were matched (2:1) based...
A chest tube is a flexible plastic that inserted through the wall and into pleural space or mediastinum. It used to remove air in case of pneumothorax fluid such as effusion, blood, chyle, pus when empyema occurs from intrathoracic space. also known Bülau drain an intercostal catheter. Insertion tubes widely performed by radiologists, pulmonary physicians thoracic surgeons. Large catheters small are based on each situation medical doctor encounters. In current review we will focus systems use.
Patients with Chronic Obstructive Pulmonary Disease (COPD) and / or Sleep Apnea (OSA) often complain about sleepiness, fatigue, anxiety depression. However, common screening questionnaires, like Epworth Sleepiness Scale (ESS), Fatigue Severity (FSS) Hospital Anxiety Depression (HADS) have not been previous evaluated in patients overlap–coexisting COPD OSA–syndrome versus OSA alone. Our study compared ESS, FSS HADS between overlap syndrome OSA, before after treatment Continuous Positive...
Background: Gender affects the clinical presentation of obstructive sleep apnea (OSA). The classic OSA symptoms, such as sleepiness, snoring, and apnea, are not so frequent in women. Objectives: To evaluate possible gender differences questionnaires used for prediction, Epworth Sleepiness Scale (ESS), STOP, STOP Bang (SB), Berlin Questionnaire (BQ), Athens Insomnia (AIS), Fatigue (FS). Methods: 350 males were matched with women referred to a clinic, according severity. All responded...
Continuous positive airway pressure (CPAP) is the most effective method for treating obstructive sleep apnea syndrome (OSAS) and alleviating symptoms. Improved quality with CPAP therapy might also contribute to attenuated systemic inflammation improved endothelial function, subsequent reduction of cardiovascular risk. The aim this study was assess effect 3-month on brachial artery flow-mediated dilation (FMD) plasma C-reactive protein (CRP) levels in patients OSAS.Our group consisted 38 male...
Pneumomediastinum is a rare clinical entity that concerns the clinicians in emergency department. We present case of patient with spontaneous pneumomediastinum (Hamman's syndrome) presented to our hospital's department cervical subcutaneous emphysema. A conservative treatment observation was performed. The after 24 hours discharged suggested follow-up.
High-flow oxygen through nasal cannula (HFNC) provides adequate oxygenation and can be an alternative to noninvasive ventilation (NIV) for patients with hypoxemic respiratory failure. The aim of the present study was assess efficacy HFNC versus NIV in hypercapnic Patients (n = 40) who were admitted Emergency Department Alexandra Hospital due failure (PaCO2 ≥ 45 mmHg) randomized assigned into two groups, i.e., intervention group (use HFNC, n 20) a control NIV, 20). During their...
A pacemaker (PM) (or artificial PM, so as not to be confused with the heart's natural PM) is a medical device that uses electrical impulses, delivered by electrodes contracting heart muscles, regulate beating of heart. The primary purpose this maintain an adequate rate, either because PM fast enough, or there block in conduction system. Modern PMs are externally programmable and allow cardiologist select optimum pacing modes for individual patients. Some combine defibrillator single...