A5074560705- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Sleep and Wakefulness Research
- Sleep and related disorders
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Visual perception and processing mechanisms
- Circadian rhythm and melatonin
- Pregnancy and preeclampsia studies
- Child and Adolescent Health
- Early Childhood Education and Development
- Obstructive Sleep Apnea Research
- Retinal Development and Disorders
- Obesity, Physical Activity, Diet
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Birth, Development, and Health
- Renal and Vascular Pathologies
Rigshospitalet
2016-2022
Glostrup Hospital
2019-2021
University of Copenhagen
2017-2019
To determine the myopia prevalence in a Danish cohort aged 16-17 years and its relation to physical activity use of screen-based electronic devices.The Copenhagen Child Cohort 2000 Eye Study is prospective, population-based, observational study. Information about screen devices was obtained using questionnaires. Myopia defined as non-cycloplegic subjective spherical equivalent refraction ≤-0.50 D right eye.We included 1443 participants (45% boys) with median age (±IQR) 16.6 (±0.3). The 25%...
The hypocretin/orexin neuropeptides (hcrt) are key players in the control of sleep and wakefulness evidenced by fact that lack hcrt leads to disorder Narcolepsy Type 1. Sleep disturbances common mood disorders, has been suggested be poorly regulated depressed subjects. To study seasonal variation levels, we obtained data on hcrt-1 levels cerebrospinal fluid (CSF) from 227 human individuals evaluated for central hypersomnias at a Danish center. samples were taken over 4 year timespan, morning...
The purpose of the study was to examine 5-year changes in eyes with optic disc drusen at baseline on optical coherence tomography (OCT) scans and relation incident hyperreflective prelaminar lines.The included children who presented baseline, when participants were aged 11-12 years, again 5 years later. Grading for made all. lines all follow-up baseline. Analyses associations scleral canal diameter a nested control group 115 without drusen. Data are reported as number having least one or...
Abstract Background Myopic eyes are longer than nonmyopic and have thinner choroids. The purpose of present study was to investigate whether a subfoveal choroid at 11 years age predicted axial eye elongation myopia during adolescence. Methods Longitudinal, population-based observational study. Axial length measured using an interferometric device choroidal thickness by spectral-domain optical coherence tomography. Myopia defined as non-cycloplegic subjective spherical equivalent refraction ≤...
To evaluate the prevalence of amblyopia and associated biometric factors in Danish children. Determination best-corrected visual acuity (BCVA) using ETDRS charts, non-cycloplegic subjective refractioning guided by automated refractometry, axial length corneal curvature, fundus photography optical coherence tomography (OCT) 1335 children from population-based Copenhagen Child Cohort 2000 (CCC2000) Eye Study. Birth data were obtained Medical Registry. The mean (±SD) age was 11.7 (±0.4) years,...
Purpose: We describe changes in choroidal thickness from age 11 to 16 years and its association with ocular biometrics body development. Method: In this longitudinal, population-based observational study, was measured subfoveally 1- 3-mm temporal thereof using enhanced depth imaging spectral domain optical coherence tomography. Analyses were stratified by sex adjusted for the time of day that scan performed. Results: The study included 687 participants (304 boys). Median (interquartile range...
To examine cone density in relation to gestational and morphological parameters the Copenhagen Child Cohort (CCC2000).The macula was imaged using adaptive optics 1,296 adolescents aged 16-17 years. Axial length distance visual acuity were determined. Absolute angular photoreceptor analysed for an 80 × 80-pixel area, 2 degrees temporal fovea. Association with axial linear regression. Correlation described a Pearson correlation coefficient. Associations of parameters, maternal smoking, sex age...
To study the thickness of retinal arteriolar walls in a population-based cohort adolescents.This cross-sectional, observational included 1217 participants aged 16-17 years from Copenhagen Child Cohort 2000 Study. The wall and lumen diameter major branch arteriole were measured using adaptive optics imaging. wall-to-lumen ratio was analyzed relation to blood pressure body composition variables general linear model. Overall population, found decrease by 0.49% per μm increase (P < 0.0001) all...