A5020757748- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Psychosomatic Disorders and Their Treatments
- Bipolar Disorder and Treatment
- Autism Spectrum Disorder Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Infant Health and Development
- Digital Mental Health Interventions
- Eating Disorders and Behaviors
- Child and Animal Learning Development
- Tryptophan and brain disorders
- Adolescent and Pediatric Healthcare
- Obesity, Physical Activity, Diet
- Attention Deficit Hyperactivity Disorder
- Family and Disability Support Research
- Early Childhood Education and Development
- Child Nutrition and Feeding Issues
- Obsessive-Compulsive Spectrum Disorders
- Child and Adolescent Health
- Behavioral and Psychological Studies
- Functional Brain Connectivity Studies
- Circadian rhythm and melatonin
- Suicide and Self-Harm Studies
- Infant Development and Preterm Care
Mental Health Services
2014-2024
Capital Region of Denmark
2014-2024
Copenhagen University Hospital
2013-2024
Lundbeck Foundation
2022
Region of Southern Denmark
2018-2021
Kongsberg Innovasjon (Norway)
2020-2021
University of Southern Denmark
2019-2020
Maastricht University
2020
University Medical Center Utrecht
2020
University of Copenhagen
2014-2018
Knowledge on the significance of childhood psychotic symptoms and experiences (PE) is still limited. This study aimed to investigate prevalence clinical PE in preadolescent children from general population by use in-depth psychopathological interviews comprehensive diagnostic assessments.We investigated 1,632 population-based Copenhagen Child Cohort 2000. were measured semistructured using K-SADS-PL-items affective symptoms, each symptom scored as not present versus likely or definitely...
A large group of psychiatric patients suffer from auditory hallucinations (AH) despite relevant treatment regimens. In mental health populations, AH tend to be verbal (AVH) and the content critical or abusive. Trials employing immersive virtual reality (VR) treat disorders are emerging. The aim this scoping review is provide an overview clinical trials utilizing VR in document knowledge gaps literature. PubMed, Cochrane Library, Embase were searched for studies reporting on use target AH. 16...
Objective: Psychotic experiences affect more than 10% of children and often co-occur with nonpsychotic mental disorders. However, longitudinal studies the outcome psychotic based on unbiased information health service use psychotropic medications are scarce. The authors investigated whether at ages 11–12 predicted a psychiatric diagnosis or treatment by 16–17. Methods: In register-based follow-up study Copenhagen Child Cohort 2000, total 1,632 were assessed for in face-to-face interviews....
Children at familial high-risk of schizophrenia and bipolar disorder have an elevated prevalence mental disorders but studies children within a narrow age range are lacking there few conjoint these two groups. Knowledge on their health is important for prevention early intervention.The authors examined global functioning in (FHR-SZ) (FHR-BP) compared with population-based controls. In longitudinal cohort study, 450 (FHR-SZ, n = 171; FHR-BP, 104; controls, 175), were assessed Axis I baseline...
<sec> <title>BACKGROUND</title> Social anxiety disorder (SAD) and agoraphobia are common, impairing conditions often treated with cognitive behavioral therapy (CBT), in which exposure is a core element. Virtual reality (VRE) has shown promise as flexible alternative to in-vivo exposure. </sec> <title>OBJECTIVE</title> This trial evaluated the efficacy of group CBT VRE (VR-CBT) versus for treating SAD clinical settings. <title>METHODS</title> In this randomized, parallel-group,...
Psychotic experiences (PE) in individuals of the general population are hypothesized to mark early expression pathology underlying psychosis. This notion PE as an intermediate phenotype is based on premise that share genetic liability with We examined whether childhood was predicted by a family history mental disorder psychosis rather than nonpsychotic and this association differed severity PE. The study data 1632 children from birth cohort assessed at age 11–12 years use semistructured...
Background Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies children have documented that alterations ToM Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of (HyperToM) and PE children. Children this alteration infer mental states when none obviously suggested, predict behaviour on the basis these erroneous beliefs. Individuals HyperToM do not appear a conceptual deficit (i.e. lack representational...
The Strengths and Difficulties Questionnaire (SDQ) is a brief, widely used instrument to screen for mental health problems in children adolescents. SDQ predictive algorithms developed the SDQ, synthesize information from multiple informants regarding psychiatric symptoms their impact on daily life. This study aimed explore validity of preschool age predict disorders preadolescence. population comprises 1176 Copenhagen Child Cohort 2000 (CCC2000) assessed at 5–7 years by reassessed 11–12 with...
Objective: Psychotic experiences are common in children and adolescents associated with concurrent subsequent psychopathology. Most findings originate from general population studies, whereas little is known of the clinical outcomes psychotic at familial high risk psychosis. We examined prevalence middle childhood whether early developmental pathways predicted mental disorders schizophrenia (FHR-SZ), bipolar disorder (FHR-BP), a population-based control group. Methods: In longitudinal cohort...
Knowledge on the risk mechanisms of psychotic experiences (PE) is still limited. The aim this population-based study was to explore developmental markers PE with a particular focus specificity hyper-theory-of-mind (HyperToM) as correlate opposed any mental disorder.We assessed 1630 children from Copenhagen Child Cohort 2000 regarding and HyperToM at follow-up 11-12 years. Mental disorders were diagnosed by clinical ratings based standardized parent-, teacher- self-reported psychopathology....
Objective: We have tested the relapse‐preventive effect of citalopram when compared with placebo in 282 patients Seasonal Affective Disorder (SAD) responding to 1 week light therapy. Method: The response rate 1‐week therapy and relapse during continuation phase 15 weeks were assessed by use Hamilton Depression Rating Scale (HAM‐D 17 ), six‐item subscale 6 Melancholia (MES), combined HAM‐D/SIGH‐SAD. Results: was 62.5% on HAM‐D , 56.1% HAM‐D/SIGH‐SAD, 52.8% MES. In phase, found superior all...
Aim Valid instruments for the early identification of psychotic experiences (PE) and symptoms in youths are urgently needed large‐scale preventive interventions. A new section The‐Development‐and‐Well‐Being Assessment (DAWBA) measuring child self‐reported PE has yet to be validated. The current study aimed investigate concurrent validity DAWBA‐based (PE‐S) with regard interview‐based measures (PE‐I). Methods Participants were 1571 (47.8% male) children age 11 12 years from Copenhagen Child...
Abstract Background Social Anxiety Disorder (SAD) is characterized by an intense fear of negative judgement others. Cognitive Behavioral Therapy (CBT) recommended for treatment, but a substantial part individuals with SAD either do not seek treatment or drop-out. CBT Virtual Reality (VR)-based exposure has several advantages compared to traditional methods, mainly due increased control situational elements. The aim the current study develop program containing VR-based exposure. intervention...
Psychotic experiences (PEs) are common in the general population preadolescence. The implications of PEs on socioeconomic outcomes, including educational attainment, scarcely described. We aimed to estimate how preadolescent were associated with later healthcare costs, school performance, and health-related quality life (HRQoL) adolescence. A total 1607 preadolescents from Copenhagen Child Cohort 2000 assessed for at age 11-12 years followed up over 5 using register-based data mental somatic...
Tetranectin is a recently described human plasma protein, which found in most secretory cells throughout the body, including neutrophils. We present evidence for presence of tetranectin monocytes and macrophages as well, that these upon adherence or weak stimulation release 20 kDa protein identified by immunoblotting. The amount released 3–18 ng/h/10 6 monocytes. possible influence on cellular functions was tested migration oxidative metabolism assays, Monocyte spontaneous significantly...
Bullying and poor theory of mind (ToM) are both considered to negatively impact academic performance. However, it is unclear if they have separate effects.The aim the current study was examine potentially associations bullying ToM with performance.A general population sample 1,170 children aged 11-12 years.Information on bullying, type involvement (none, victim (only), bully victim-bully (both)), ToM, estimated intelligence obtained at face-to-face assessments. Information performance from...
Health anxiety (HA) is an increasing public health problem related to increased service costs, and associated with functional somatic symptoms (FSS) considerable personal suffering. Abnormal bodily experiences which may resemble HA FSS are common in psychotic disorders, but a potential link between psychosis vulnerability childhood largely unexplored. The current study estimates the association subclinical (PE) general population cohort of preadolescents.The consisted 1,572 11-12-year-old...