Carsten Hjorthøj

ORCID: 0000-0002-6943-4785
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About
Contact & Profiles
Research Areas
  • Schizophrenia research and treatment
  • Bipolar Disorder and Treatment
  • Cannabis and Cannabinoid Research
  • Child and Adolescent Psychosocial and Emotional Development
  • Mental Health Treatment and Access
  • Mental Health and Psychiatry
  • Homelessness and Social Issues
  • Mental Health and Patient Involvement
  • Mental Health Research Topics
  • Suicide and Self-Harm Studies
  • Adolescent and Pediatric Healthcare
  • Maternal Mental Health During Pregnancy and Postpartum
  • Psychiatric care and mental health services
  • Substance Abuse Treatment and Outcomes
  • Psychosomatic Disorders and Their Treatments
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Functional Brain Connectivity Studies
  • Workplace Health and Well-being
  • Tryptophan and brain disorders
  • Family Caregiving in Mental Illness
  • Health, psychology, and well-being
  • Food Security and Health in Diverse Populations
  • Health Systems, Economic Evaluations, Quality of Life
  • Employment and Welfare Studies
  • Cardiac Health and Mental Health

Mental Health Services
2016-2025

Capital Region of Denmark
2015-2025

Copenhagen University Hospital
2016-2025

University of Copenhagen
2015-2025

Lundbeck Foundation
2015-2024

The Capital Region Pharmacy
2023-2024

Gentofte Hospital
2019-2024

Centre for Mental Health
2021-2024

Aarhus University Hospital
2024

Aarhus University
2018-2024

The authors investigated the rates of conversion to schizophrenia and bipolar disorder after a substance-induced psychosis, as well risk factors for conversion.All patient information was extracted from Danish Civil Registration System Psychiatric Central Research Register. study population included all persons who received diagnosis psychosis between 1994 2014 (N=6,788); patients were followed until first occurrence or death, emigration, August 2014. Kaplan-Meier method used obtain...

10.1176/appi.ajp.2017.17020223 article EN American Journal of Psychiatry 2017-11-28

Abstract Background Previous research suggests an increase in schizophrenia population attributable risk fraction (PARF) for cannabis use disorder (CUD). However, sex and age variations CUD suggest the importance of examining differences PARFs subgroups. Methods We conducted a nationwide Danish register-based cohort study including all individuals aged 16–49 at some point during 1972–2021. status was obtained from registers. Hazard ratios (HR), incidence (IRR), were estimated. Joinpoint...

10.1017/s0033291723000880 article EN cc-by Psychological Medicine 2023-05-04

The OPUS 20-year follow-up is the longest of a randomized clinical trial testing early intervention services (EIS) among individuals with first-episode schizophrenia spectrum disorder.

10.1001/jamapsychiatry.2022.5164 article EN JAMA Psychiatry 2023-02-22

Introduction : Specialized early intervention programs such as The Danish OPUS treatment are efficient in treating patients with a first episode of psychosis (FEP) at least after 2 and 5 years. Few studies have examined long-term outcomes these interventions. Aim To examine the effect years vs usual (TAU) within an FEP cohort, 10 inclusion into trial. Methods From 1998 to 2000, participants were randomized or TAU. Ten later, we conducted comprehensive interviews performed register-based...

10.1093/schbul/sbu155 article EN Schizophrenia Bulletin 2014-11-07

Life expectancy in patients with schizophrenia is reduced by 20 years for men and 15 women compared to the general population. About 60% of excess mortality due physical illnesses, cardiovascular disease being dominant. CHANGE was a randomized, parallel-group, superiority, multi-centre trial blinded outcome assessment, testing efficacy an intervention aimed improve risk profile hereby potentially reduce mortality. A total 428 spectrum disorders abdominal obesity were recruited centrally...

10.1002/wps.20318 article EN World Psychiatry 2016-06-01

To estimate and test associations between substance use disorders (SUDs) both completed suicides suicide attempts in a population with severe mental illness.Register-based cohort study adjusted Cox regression of as time-varying covariates.Denmark.People born Denmark since 1955 diagnosis schizophrenia (n = 35 625), bipolar disorder 9279), depression 72 530) or personality 63 958).Treated SUDs alcohol illicit substances identified treatment registers; attempt the Cause Death register....

10.1111/add.13788 article EN Addiction 2017-02-13

<b>Objective</b>&nbsp;To compare the effects of five years specialised early intervention (SEI) treatment for first episode schizophrenia spectrum disorder with standard two SEI plus three as usual. <b>Design</b>&nbsp;Randomised, superiority, parallel group trial blinded outcome assessment. Randomisation was centralised and computerised concealed randomisation sequence carried out at an external site. <b>Setting</b>&nbsp;Participants were recruited from six OPUS teams in Denmark between 2009...

10.1136/bmj.i6681 article EN cc-by-nc BMJ 2017-01-12

Cannabis use and potency of cannabis have increased during the past 2 decades. If association between schizophrenia is causal, this should be reflected in an increase proportion cases being attributable to cannabis, population-attributable risk fraction (PARF).To determine whether PARF for disorder has over time.This nationwide, register-based historical prospective cohort study included all people Denmark born before December 31, 2000, who were alive 16 years or older at some point from...

10.1001/jamapsychiatry.2021.1471 article EN JAMA Psychiatry 2021-07-21
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