A5064865113- Air Quality and Health Impacts
- Mercury impact and mitigation studies
- Heavy Metal Exposure and Toxicity
- Oral microbiology and periodontitis research
- Per- and polyfluoroalkyl substances research
- Dental Health and Care Utilization
- Oral Health Pathology and Treatment
- Genetic Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- Statistical Methods and Bayesian Inference
- Antifungal resistance and susceptibility
- Statistical Methods and Inference
- Dental Implant Techniques and Outcomes
- Health, Environment, Cognitive Aging
- Toxic Organic Pollutants Impact
- Birth, Development, and Health
- Effects and risks of endocrine disrupting chemicals
- Vitamin D Research Studies
- Medical and Biological Ozone Research
- Climate Change and Health Impacts
- Economic and Environmental Valuation
- Fluoride Effects and Removal
- Cancer, Hypoxia, and Metabolism
- Dental Erosion and Treatment
- Neurological disorders and treatments
University of Copenhagen
2015-2024
Rigshospitalet
1989-2023
Copenhagen University Hospital
2009-2023
ORCID
2023
Aarhus University
1975-2022
Aarhus University Hospital
1978-2022
Regional Hospital West Jutland
2019
Danish Ramazzini Center
2019
Danish Cancer Society
2019
Danish Multiple Sclerosis Center
2016
<h3>Context</h3>Perfluorinated compounds (PFCs) have emerged as important food contaminants. They cause immune suppression in a rodent model at serum concentrations similar to those occurring the US population, but adverse health effects of PFC exposure are poorly understood.<h3>Objective</h3>To determine whether is associated with antibody response childhood vaccinations.<h3>Design, Setting, and Participants</h3>Prospective study birth cohort from National Hospital Faroe Islands. A total...
Background: The incidence of acute hamstring injuries is high in several sports, including the different forms football. Purpose: authors investigated preventive effect eccentric strengthening muscles using Nordic exercise compared with no additional on rate male soccer players. Study Design: Randomized controlled trial; Level evidence, 1. Methods: Fifty Danish professional and amateur teams (942 players) were allocated to an intervention group (461 or a control (481 players). Players...
Summary. Logistic regression with random effects is used to study the relationship between explanatory variables and a binary outcome in cases nonindependent outcomes. In this paper, we examine detail interpretation of both fixed parameters. As heterogeneity measures, parameters included model are not easily interpreted. We discuss different alternative measures suggest using median odds ratio measure that function original The allows simple interpretation, terms well‐known ratios, greatly...
Blood pressure in childhood is an important determinant of hypertension risk later life, and methylmercury exposure a potential environmental factor. A birth cohort 1,000 children from the Faroe Islands was examined for prenatal to methylmercury, at age 7 years, blood pressure, heart rate, rate variability were determined. After adjustment body weight, diastolic systolic increased by 13.9 mmHg [95% confidence limits (CL) = 7.4, 20.4] 14.6 (95% CL 8.3, 20.8), respectively, when cord mercury...
(1970). Denture Stomatitis I. The Etiology in Relation to Trauma and Infection. Acta Odontologica Scandinavica: Vol. 28, No. 1, pp. 71-92.
The purpose of this study has been to assess the prevalence denture stomatitis and candida infection in an elderly Danish population. Ten percent population above age 65 a community was selected randomly. group consisted 465 persons wearing removable maxillary denture, who were examined their homes. Yeasts isolated by oral swabs for cultivation mucosal scrapings microscopy. 65%. Yeasts, especially C. albicans, cultivated most wearers with (Group 1) or clinically normal palatal mucosa 2)....
Perfluorinated alkylate substances (PFASs) are highly persistent and may cause immunotoxic effects. PFAS-associated attenuated antibody responses to childhood vaccines be affected by PFAS exposures during infancy, where breastfeeding adds exposures. Of 490 members of a Faroese birth cohort, 275 349 participated in clinical examinations provided blood samples at ages 18 months 5 years. concentrations were measured the examinations. Using information on duration breastfeeding, serum-PFAS...
The mercury concentration in blood or scalp hair has been widely used as a biomarker for methlimercury exposure. Becasue of the increased risks associated with exposures during prenatal and early postnatal development, results must be interpreted regard to age-dependent susceptibillity. authors compared regression coefficients five sets exposure biomarkers 917 children from Faroe Islands examined at birth, 1 year, 7 years. Outcome varibales were neuropsychologic exemination carried out...
OBJECTIVE: To evaluate the relationship between oral health status and nutritional deficiency. DESIGN: Cross-sectional clinical study. SUBJECTS: 324 institutionalized frail older adults (mean age 85). MEASUREMENTS: Structured examination including an evaluation of mucosa, periodontal state, caries prevalence denture quality. The was assessed using serum albumin concentration body mass index. Physical dependence Barthel identify disorders associated with markers malnutrition we performed...
Methylmercury (MeHg), a worldwide contaminant found in fish and seafood, has been linked to an increased risk of cardiovascular mortality.We examined 42 Faroese whaling men (30-70 years age) assess possible adverse effects within wide range MeHg exposures from consumption pilot whale meat.We assessed exposure levels mercury analysis toenails whole blood (obtained at the time clinical examination), hair sample collected 7 previously. Outcome measures included heart rate variability (HRV),...
Fish and seafood provide important nutrients but may also contain toxic contaminants, such as methylmercury. Advisories against pollutants therefore conflict with dietary recommendations. In resolving this conundrum, most epidemiologic studies little guidance because they address either nutrient benefits or mercury toxicity, not both.Impact on the same health outcomes by two exposures originating from food source provides a classical example of confounding. To explore extent bias, we applied...
Background Developmental exposure to polychlorinated biphenyls (PCBs) has been implicated as a possible cause of deficient immune function in children. This study was designed assess whether prenatal and postnatal PCBs impacts on antibody response childhood immunizations. Methods Findings Two birth cohorts were formed the Faroe Islands, where exposures vary widely, because traditional diets may include whale blubber contaminated with PCBs. Prenatal determined from maternal concentrations...
Background— Heritability may play a role in nonfamilial atrial fibrillation (AF). We hypothesized that monozygotic (MZ) twin whose co-twin was diagnosed with AF would have an increased risk of the disease compared dizygotic (DZ) same situation. Methods and Results— A sample 1137 same-sex pairs (356 MZ 781 DZ pairs) which one or both members were identified The Danish Twin Registry. Concordance rates twice as high for than regardless sex (22.0% versus 11.6%, P <0.0001). In Cox regression...
The aim of this prospective study was to investigate whether occupational pesticide exposure during pregnancy causes adverse effects on the reproductive development in male infants.Pregnant women employed greenhouses Denmark were consecutively recruited, and 113 mother-son pairs included. mothers categorized as occupationally exposed (91 sons) or unexposed (22 pesticides pregnancy. Testicular position volume, penile length, urethral opening determined at 3 months age using standardized...
Postnatal exposure to perfluorinated alkylate substances (PFASs) is associated with lower serum concentrations of specific antibodies against certain childhood vaccines at 7 y.We prospectively followed a Faroese birth cohort determine these associations 13 y.In 516 subjects (79% eligible members) who were years old, PFASs and diphtheria tetanus measured compared data from the previous examination y. Multiple regression analyses structural equation models applied association between postnatal...
Due to global mercury pollution and the adverse health effects of prenatal exposure methylmercury (MeHg), an assessment economic benefits prevented developmental neurotoxicity is necessary for any cost-benefit analysis.Distributions hair-Hg concentrations among women reproductive age were obtained from DEMOCOPHES project (1,875 subjects in 17 countries) literature data (6,820 8 countries). The exposures assumed comply with log-normal distributions. Neurotoxicity estimated a linear...