Anders D. Børglum

ORCID: 0000-0001-8627-7219
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About
Contact & Profiles
Research Areas
  • Genetic Associations and Epidemiology
  • Genetics and Neurodevelopmental Disorders
  • Autism Spectrum Disorder Research
  • Attention Deficit Hyperactivity Disorder
  • Epigenetics and DNA Methylation
  • Genomic variations and chromosomal abnormalities
  • Genomics and Rare Diseases
  • Birth, Development, and Health
  • Bipolar Disorder and Treatment
  • Health, Environment, Cognitive Aging
  • Genetic Mapping and Diversity in Plants and Animals
  • Adolescent and Pediatric Healthcare
  • Congenital heart defects research
  • Child and Adolescent Psychosocial and Emotional Development
  • Tryptophan and brain disorders
  • Bioinformatics and Genomic Networks
  • Cognitive Abilities and Testing
  • Genetic Syndromes and Imprinting
  • Functional Brain Connectivity Studies
  • Schizophrenia research and treatment
  • Diet and metabolism studies
  • Asthma and respiratory diseases
  • Metabolism and Genetic Disorders
  • Nutrition, Genetics, and Disease
  • Genetic and phenotypic traits in livestock

Lundbeck Foundation
2016-2025

Aarhus University
2016-2025

Genetic Analysis (Norway)
2024

University of Utah
2023

Virginia Commonwealth University
2019-2023

Huntsman (United States)
2023

Central Denmark Region
2019-2022

Copenhagen University Hospital
2016-2022

Sankt Hans Hospital
2022

University of Copenhagen
2022

F. Kyle Satterstrom Jack A. Kosmicki Jiebiao Wang Michael S. Breen Silvia De Rubeis and 95 more Joon‐Yong An Minshi Peng Ryan L. Collins Jakob Grove Lambertus Klei Christine Stevens Jennifer Reichert Maureen Mulhern Mykyta Artomov Sherif Gerges Brooke Sheppard Xinyi Xu Aparna Bhaduri Utku Norman Harrison Brand Grace Schwartz Rachel Nguyen Elizabeth E. Guerrero Caroline Dias Catalina Betancur Edwin H. Cook Louise Gallagher Michael Gill James S. Sutcliffe Audrey Thurm Michael E. Zwick Anders D. Børglum Matthew W. State A. Ercüment Çiçek Michael E. Talkowski David J. Cutler Bernie Devlin Stephan Sanders Kathryn Roeder Mark J. Daly Joseph D. Buxbaum Branko Aleksić Richard Anney Mafalda Barbosa Somer Bishop Alfredo Brusco Jonas Bybjerg‐Grauholm Ángel Carracedo Marcus C.Y. Chan Andreas G. Chiocchetti Brian Hon‐Yin Chung Hilary Coon Michael L. Cuccaro Aurora Currò Bernardo Dalla Bernardina Ryan N. Doan Enrico Domenici Shan Dong Chiara Fallerini Montserrat Fernández Prieto Giovanni Battista Ferrero Christine M. Freitag Menachem Fromer J. Jay Gargus Daniel H. Geschwind Elisa Giorgio Javier González‐Peñas Stephen J. Guter Danielle Halpern Emily Hansen‐Kiss Xin He Gail E. Herman Irva Hertz‐Picciotto David M. Hougaard Christina M. Hultman Iuliana Ionita‐Laza Suma Jacob Jesslyn Jamison Astanand Jugessur Miia Kaartinen Gun Peggy Knudsen Alexander Kolevzon Itaru Kushima So Lun Lee Terho Lehtimäki Elaine T. Lim Carla Lintas W. Ian Lipkin Diego Lopergolo Fátima Lopes Yunin Ludeña Patrı́cia Maciel Per Magnus Behrang Mahjani Nell Maltman Dara S. Manoach Gal Meiri Idan Menashe Judith Miller Nancy J. Minshew

10.1016/j.cell.2019.12.036 article EN publisher-specific-oa Cell 2020-01-23

10.1038/nature08186 article EN Nature 2009-07-01

Genes overlap across psychiatric disease Many genome-wide studies have examined genes associated with a range of neuropsychiatric disorders. However, the degree to which genetic underpinnings these diseases differ or is unknown. Gandal et al. performed meta-analyses transcriptomic covering five major disorders and compared cases controls identify coexpressed gene modules. From this, they found that some share global expression patterns. This in polygenic traits may allow for better diagnosis...

10.1126/science.aad6469 article EN Science 2018-02-09
Douglas M. Ruderfer Stephan Ripke Andrew McQuillin James Boocock Eli A. Stahl and 95 more Jennifer M. Whitehead Pavlides Niamh Mullins Alexander W. Charney Anil P. S. Ori Loes M. Olde Loohuis Enrico Domenici Arianna Di Florio Sergi Papiol János Kálmán Vassily Trubetskoy Rolf Adolfsson Ingrid Agartz Esben Agerbo Huda Akil Diego Albani Margot Albus Martin Alda Madeline Alexander Ney Alliey‐Rodriguez Thomas D. Als Farooq Amin Adebayo Anjorin María J. Arranz Swapnil Awasthi Silviu‐Alin Bacanu Judith A. Badner Marie Bækvad‐Hansen Steven C. Bakker Gavin Band Jack D. Barchas Inês Barroso Nicholas Bass Michael Bauer Bernhard T. Baune Martin Begemann Céline Bellenguez Richard A. Belliveau Frank Bellivier Stephan Bender Judit Bene Sarah E. Bergen Wade H. Berrettini Elizabeth Bevilacqua Joanna M. Biernacka Tim B. Bigdeli Donald W. Black Hannah Blackburn Jenefer M. Blackwell Douglas Blackwood Carsten Bøcker Pedersen Michael Boehnke Marco P. Boks Anders D. Børglum Elvira Bramon Gerome Breen Matthew A. Brown Richard Bruggeman Nancy G. Buccola Randy L. Buckner Monika Budde Brendan Bulik‐Sullivan Suzannah J. Bumpstead William E. Bunney Margit Burmeister Joseph D. Buxbaum Jonas Bybjerg‐Grauholm William Byerley Wiepke Cahn Guiqing Cai Murray J. Cairns Dominique Campion Rita M. Cantor Vaughan J. Carr Noa Carrera Juan P. Casas Miguel Casas Stanley V. Catts Pablo Cervantes Kimberley D. Chambert Raymond C. K. Chan Eric Chen Ronald Y.L. Chen Wei Cheng Eric F.C. Cheung Siow Ann Chong Toni‐Kim Clarke C. Robert Cloninger David Cohen Nadine Cohen Jonathan R. I. Coleman David Collier Paul Cormican William Coryell Nicholas John Craddock David W. Craig

10.1016/j.cell.2018.05.046 article EN publisher-specific-oa Cell 2018-06-01
Alexander Gusev Sang Lee Gosia Trynka Hilary K. Finucane Bjarni J. Vilhjálmsson and 95 more Han Xu Chongzhi Zang Stephan Ripke Brendan Bulik‐Sullivan Eli A. Stahl Anna K. Kähler Christina M. Hultman Shaun Purcell Steven A. McCarroll Mark J. Daly Bogdan Paşaniuc Patrick F. Sullivan Benjamin M. Neale Naomi R. Wray Soumya Raychaudhuri Alkes L. Price Stephan Ripke Benjamin M. Neale Aiden Corvin James Walters Kai-How Farh Peter Holmans Phil Lee Brendan Bulik‐Sullivan David Collier Hailiang Huang Tune H. Pers Ingrid Agartz Esben Agerbo Margot Albus Madeline Alexander Farooq Amin Silviu‐Alin Bacanu Martin Begemann Richard A. Belliveau Judit Bene Sarah E. Bergen Elizabeth Bevilacqua Tim B. Bigdeli Donald W. Black Anders D. Børglum Richard Bruggeman Nancy G. Buccola Randy L. Buckner William Byerley Wiepke Cahn Guiqing Cai Dominique Campion Rita M. Cantor Vaughan J. Carr Noa Carrera Stanley V. Catts Kimberly D. Chambert Raymond Chan Ronald Y.L. Chen Eric Chen Wei Cheng Eric Cheung Siow Ann Chong C. Robert Cloninger David Cohen Nadine Cohen Paul Cormican Nick Craddock James J. Crowley David Curtis Michael H. Davidson Kenneth L. Davis Franziska Degenhardt Jurgen Del‐Favero Lynn E. DeLisi Ditte Demontis Dimitris Dikeos Timothy G. Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Naser Durmishi Peter Eichhammer Johan G. Eriksson Valentina Escott‐Price Laurent Essioux Ayman H. Fanous Martilias S. Farrell Josef Frank Lude Franke Robert Freedman Nelson B. Freimer Marion Friedl Joseph I. Friedman Menachem Fromer Giulio Genovese Lyudmila Georgieva

10.1016/j.ajhg.2014.10.004 article EN publisher-specific-oa The American Journal of Human Genetics 2014-11-01
Tarjinder Singh Timothy Poterba David Curtis Huda Akil Mariam Al Eissa and 95 more Jack D. Barchas Nicholas Bass Tim B. Bigdeli Gerome Breen Evelyn J. Bromet P.F. Buckley William E. Bunney Jonas Bybjerg‐Grauholm William Byerley Sinéad B. Chapman Wei J. Chen Claire Churchhouse Nicholas Craddock Caroline Cusick Lynn E. DeLisi Sheila Dodge Michael Escamilla Saana Eskelinen Ayman H. Fanous Stephen V. Faraone Alessia Fiorentino Laurent C. Francioli Stacey Gabriel Diane Gage Sarah A. Gagliano Taliun Andrea Ganna Giulio Genovese David C. Glahn Jakob Grove Mei‐Hua Hall Eija Hämäläinen Henrike Heyne Matti Holi David M. Hougaard Daniel P. Howrigan Hailiang Huang Hai‐Gwo Hwu René S. Kahn Hyun Min Kang Konrad J. Karczewski George Kirov James A. Knowles Francis S. Lee Douglas S. Lehrer Francesco Lescai Dolores Malaspina Stephen R. Marder Steven A. McCarroll Andrew M. McIntosh Helena Medeiros Lili Milani Christopher P. Morley Derek W. Morris Preben Bo Mortensen R Myers Merete Nordentoft Niamh L. O’Brien Ana Maria Olivares Döst Öngür Willem H. Ouwehand Duncan S. Palmer Tiina Paunio Digby Quested Mark Hyman Rapaport Elliott Rees Brandi Rollins F. Kyle Satterstrom Alan F. Schatzberg Edward M. Scolnick Laura J. Scott Sally I. Sharp Pamela Sklar Jordan W. Smoller Janet L. Sobell Matthew Solomonson Eli A. Stahl Christine Stevens Jaana Suvisaari Grace Tiao Stanley J. Watson Nicholas A. Watts Douglas Blackwood Anders D. Børglum Bruce M. Cohen Aiden Corvin Tõnu Esko Nelson B. Freimer Stephen J. Glatt Christina M. Hultman Andrew McQuillin Aarno Palotie Carlos N. Pato Michele T. Pato Ann E. Pulver David St Clair

10.1038/s41586-022-04556-w article EN Nature 2022-04-08

We identified the α-cardiac actin gene (ACTC) as a novel disease in pedigree suffering from familial hypertrophic cardiomyopathy (FHC). Linkage analyses excluded all previously reported FHC loci possible family studied, with lod scores varying between –2.5 and –6.0. Further linkage of plausible candidate genes highly expressed adult human heart ACTC most likely gene, showing maximal score 3.6. Mutation analysis revealed an Ala295Ser mutation exon 5 close to 2 missense mutations recently...

10.1172/jci6460 article EN Journal of Clinical Investigation 1999-05-15

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a devastating inherited disorder characterized by episodic syncope and/or sudden cardiac arrest during exercise or acute emotion in individuals without structural abnormalities. Although rare, CPVT suspected to cause substantial part of deaths young individuals. Mutations RYR2, encoding the sarcoplasmic calcium channel, have been identified as causative approximately half all dominantly cases. Applying genome-wide linkage...

10.1016/j.ajhg.2012.08.015 article EN cc-by-nc-nd The American Journal of Human Genetics 2012-10-01

The Integrative Psychiatric Research (iPSYCH) consortium has established a large Danish population-based Case-Cohort sample (iPSYCH2012) aimed at unravelling the genetic and environmental architecture of severe mental disorders. iPSYCH2012 is nested within entire population born between 1981 2005, including 1 472 762 persons. This paper introduces outlines key future research directions. Cases were identified as persons with schizophrenia (N=3540), autism (N=16 146),...

10.1038/mp.2017.196 article EN cc-by-nc-nd Molecular Psychiatry 2017-09-19
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