- Attention Deficit Hyperactivity Disorder
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Neural and Behavioral Psychology Studies
- Transcranial Magnetic Stimulation Studies
- Autism Spectrum Disorder Research
- Neural dynamics and brain function
- Child and Adolescent Psychosocial and Emotional Development
- COVID-19 and Mental Health
- Vestibular and auditory disorders
- Schizophrenia research and treatment
- Neuroscience and Music Perception
- Migraine and Headache Studies
- Genetic Associations and Epidemiology
- Obsessive-Compulsive Spectrum Disorders
- Multisensory perception and integration
- Children's Physical and Motor Development
- Muscle activation and electromyography studies
- Neuroscience and Neuropharmacology Research
- Motor Control and Adaptation
- Neurological disorders and treatments
- Mental Health Research Topics
- Visual perception and processing mechanisms
- Eating Disorders and Behaviors
- Neuroscience and Neural Engineering
University of Cologne
2016-2025
University Hospital Cologne
2017-2025
Goethe University Frankfurt
2011-2024
TU Dresden
2011-2023
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2018-2023
Heidelberg University
2005-2023
University Hospital Carl Gustav Carus
2011-2023
Inserm
2021
Université Paris-Est Créteil
2021
Klinik und Poliklinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters
2014-2021
Abstract The electroencephalographic response to transcranial magnetic stimulation (TMS) recently has been established as a direct parameter of motor cortex excitability. Its N100 component was suggested reflect an inhibitory response. We investigated influences cerebral maturation on TMS‐evoked in 6‐ 10‐year‐old healthy children. used forewarned reaction time (contingent negative variation) task test the effects preparation and sensory attention amplitude. Single‐pulse TMS at 105% threshold...
Attention deficit hyperactivity disorder is one of the most frequent neuropsychiatric disorders in childhood. Transcranial magnetic stimulation studies based on muscle responses (motor-evoked potentials) suggested that reduced motor inhibition contributes to hyperactivity, a core symptom disease. Here we employed N100 component electroencephalographic response transcranial as novel marker for direct assessment cortical inhibitory processes, which has not been examined attention so far. We...
Within the field of functional magnetic resonance imaging (fMRI) neurofeedback, most studies provide subjects with instructions or suggest strategies to regulate a particular brain area, while other neuro-/biofeedback approaches often do not. This study is first investigate hypothesis that are able utilize fMRI neurofeedback learn differentially modulate signal from bilateral amygdala congruent prescribed regulation direction without an instructed suggested strategy and apply what they...
Migraine is very common in school-aged children, but despite a number of pharmacological and non-pharmacological options for prophylaxis, randomized controlled evidence children small. Evidence-based prophylactic drugs may have considerable side effects.This study was to assess efficacy butterbur root extract (Petadolex) music therapy primary school with migraine.Prospective, randomized, partly double-blind, placebo-controlled, parallel-group trial.Following 8-week baseline patients were...
Background Increased intra‐subject variability ( ISV ) in reaction times (RTs) is a promising endophenotype for attention‐deficit hyperactivity disorder ADHD and among the most robust hallmarks of disorder. has been assumed to represent an attentional deficit, either reflecting lapses attention or increased neural noise. Here, we use innovative single‐trial event‐related potential approach assess whether associated with indeed attributable attention, it related response‐related processing....
Introduction The SARS-CoV-2 pandemic has significantly impacted children and adolescents, leading to mental health challenges. Knowledge on their resources difficulties is crucial there a need for valid instruments assess psychosocial condition especially in this exceptional situation. We assessed psychopathological symptoms using the SDQ during pandemic, comparing pre-pandemic data. Our study aims understand adolescents’ strengths amidst COVID-19, evaluating SDQ’s utility crisis settings....
Abstract Background Traumatic experiences in childhood can have far-reaching and serious consequences for the development of those affected. Little is known about age- sex-specific symptom patterns children adolescents following a traumatic event. These do not always manifest symptoms that meet diagnostic criteria post-traumatic stress disorder according to ICD 10. Methods In an outpatient cohort 84 aged 6 18 years, we utilised dimensional Child Behaviour Checklist (CBCL) analyse occurring...
The diagnostic efficiency of screening instruments for adolescents with Borderline Personality Disorder (BPD)-that are applicable to its new classification in DSM-5 and ICD-11-has not yet been sufficiently studied. We examined the reliability juvenile version Impulsivity Emotion Dysregulation Scale (IES-27-J) a German-speaking sample inpatient 12-19-year-old (N = 220, including n 88 BPD 132 other mental disorders). Using receiver operating characteristic (ROC) analysis, optimal cutoff values...
Psychiatric co-morbidity is an important risk factor for chronification of primary headache into adulthood. The aim this study was to investigate the extent and clinical relevance emotional behavioural problems in children adolescents with headache. Children (n = 128) (International Headache Society, codes 1.1, 1.2, 2.1) 83 matched controls aged 6-18 years were examined by standardized dimensional psychomet-rical tests (Child Behaviour Checklist, Depression Inventory Adolescents, Anxiety...
Background Repetitive transcranial magnetic stimulation (rTMS) allows non-invasive of the human brain. However, no suitable marker has yet been established to monitor immediate rTMS effects on cortical areas in children. Objective TMS-evoked EEG potentials (TEPs) could present a well-suited for real-time monitoring. Monitoring is particularly important children where only few data about and safety are currently available. Methods In single-blind sham-controlled study, twenty-five school-aged...
Atypical visual processing of biological motion contributes to social impairments in autism spectrum disorders (ASD). However, the exact temporal sequence deficits cortical ASD has not been studied date. We used 64-channel electroencephalography study event-related potentials associated with human perception 17 children and adolescents 21 typical controls. A spatio-temporal source analysis was performed assess brain structures involved these processes. expected altered activity already...
In April 2020, the European Society for Child and Adolescent Psychiatry (ESCAP) Research Academy ESCAP Board launched first of three scheduled surveys to evaluate impact coronavirus disease 2019 (COVID-19) pandemic on child adolescent psychiatry (CAP) services in Europe assess abilities CAP centers meet new challenges brought by crisis. The survey was a self-report questionnaire, using multistage process, which sent 168 heads academic 24 countries. Eighty-two responses (56 complete) from 20...
Little is known about sexual dysfunctions associated with psychiatric disorders and psychopharmacological treatment. In the present study schizophrenic patients (n = 45, mostly under neuroleptic treatment), neurotic 50, treated without medication), methadone-substituted opiate addicts 37), normal controls 41) were included. They interviewed aid of a sex-differentiated semistructured questionnaire on function. All nearly all suffered from in at least one criterion. The three clinical groups...