A5084528202- Eating Disorders and Behaviors
- Attention Deficit Hyperactivity Disorder
- Obsessive-Compulsive Spectrum Disorders
- Genetic Associations and Epidemiology
- Obesity, Physical Activity, Diet
- Diabetes Management and Education
- Sleep and related disorders
- Tryptophan and brain disorders
- Impact of Technology on Adolescents
- Child Nutrition and Feeding Issues
- Autism Spectrum Disorder Research
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Diabetes Management and Research
- Child and Adolescent Psychosocial and Emotional Development
- Chronic Disease Management Strategies
- Birth, Development, and Health
- Regulation of Appetite and Obesity
- Mental Health Treatment and Access
- Mental Health Research Topics
- Cardiovascular Disease and Adiposity
- Functional Brain Connectivity Studies
- Diet and metabolism studies
- Neurotransmitter Receptor Influence on Behavior
- Youth Substance Use and School Attendance
Central and North West London NHS Foundation Trust
2021-2025
King's College London
2013-2025
Institute of Psychiatry and Neurology
2021
St Ann's Hospital
2020-2021
St Ann’s Hospital
2020-2021
South London and Maudsley NHS Foundation Trust
2015-2020
Bethlem Royal Hospital
2017-2020
Radboud University Nijmegen
2005-2019
Radboud University Medical Center
2005-2019
University of Colombo
2019
The association between major depressive disorder (MDD) and obesity may stem from shared immunometabolic mechanisms particularly evident in MDD with atypical features, characterized by increased appetite and/or weight (A/W) during an active episode.To determine whether subgroups of patients stratified according to the A/W criterion had a different degree genetic overlap obesity-related traits (body mass index [BMI] levels C-reactive protein [CRP] leptin).This multicenter study assembled...
Difficulties with pragmatic aspects of communication are universal across individuals autism spectrum disorders (ASDs). Here we focused on an aspect language comprehension that is relevant to social interaction in daily life: the integration speaker characteristics inferred from voice content a message. Using functional magnetic resonance imaging (fMRI), examined neural correlates voice-based inferences about speaker's age, gender or background, and sentence adults ASD matched control...
Abstract ADHD is a neuropsychiatric disorder characterized by chronic hyperactivity, inattention and impulsivity, which affects about 5% of school‐age children. persists into adulthood in at least 15% cases. It highly heritable familial influences seem strongest for persisting adulthood. However, most the genetic research has been carried out children with disorder. The gene that received attention genetics SLC6A3 / DAT1 encoding dopamine transporter. In current study we attempted to...
A bidirectional association between type 2 diabetes (T2DM) and depression has been consistently reported. Depression is associated with worse biomedical outcomes increased mortality. The mechanisms underlying the of T2DM remain unclear. One possible question we can address extent to which co-occurrence due correlated genetic and/or environmental risk factors. In this study, performed structural equation model fitting population-level data from Swedish (n=68 606) Danish (n=95 403) twin...
Eating disorders (EDs) are serious, often chronic, conditions associated with pronounced morbidity, mortality, and dysfunction increasingly affecting young people worldwide. Illness progression, stages recovery trajectories of EDs still poorly characterised. The STORY study dynamically longitudinally assesses different (restricting; bingeing/bulimic presentations) illness durations (earlier; later stages) compared to healthy controls. Remote measurement technology (RMT) active passive...
Research suggests that those caring for a loved one with an eating disorder in the UK report unmet needs and highlight areas improvement. More research is needed to understand these experiences on wider, national scale. To disseminate survey adults who had experience UK, informed by findings of smaller scale, qualitative study parents, siblings partners UK. A cross-sectional web-based was disseminated total 360 participants completed survey. Participants described care received both children...
Despite the fact that there have been many reports on benzodiazepine (BZD) dependence, consensus about its definition has not reached. Reliable prevalence data to estimate dependence liability of BZDs are therefore lacking. This study is first assess BZD in out-patient users (115-general practice (GP) patients, 124 psychiatric out-patients and 33 self-help patients) basis DSM-III-R ICD-10 substance criteria. Past year lifetime diagnoses were made by means Schedules for Clinical Assessments...
Attention deficit hyperactivity disorder (ADHD) is a common behavioral affecting children and adults. It has been suggested that gene variants related to serotonin neurotransmission are associated with ADHD. We tested the functional promoter polymorphism 5-HTTLPR seven single nucleotide polymorphisms in SLC6A4 for association ADHD 448 adult patients 580 controls from Norway. Replication attempts were performed sample of 1454 Caucasian 1302 Germany, Spain, Netherlands USA, meta-analysis was...