A5058180511- Chronic Disease Management Strategies
- Atrial Fibrillation Management and Outcomes
- Global Cancer Incidence and Screening
- Primary Care and Health Outcomes
- Colorectal Cancer Screening and Detection
- Cardiac Arrhythmias and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Cardiac Health and Mental Health
- Clinical practice guidelines implementation
- Mental Health and Psychiatry
- Health disparities and outcomes
- Mental Health Treatment and Access
- Childhood Cancer Survivors' Quality of Life
- Migration, Health and Trauma
- Maternal and Perinatal Health Interventions
- Microscopic Colitis
- Maternal Mental Health During Pregnancy and Postpartum
- Cutaneous lymphoproliferative disorders research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac and Coronary Surgery Techniques
- Traumatic Brain Injury Research
- Grief, Bereavement, and Mental Health
- Schizophrenia research and treatment
- Diabetes Management and Education
Aarhus University Hospital
2011-2025
Danish Ramazzini Center
2025
Aarhus University
2013-2023
Faculty of Public Health
2020
Danish National Institute of Public Health
2017
Aalborg University Hospital
2011
University of Minnesota
2011
Persons with mental disorders are at a higher risk than the general population for subsequent development of certain medical conditions.
Abstract Background Patients with multimorbidity are frequent users of healthcare, but fragmented care may lead to suboptimal treatment. Yet, this has never been examined across healthcare sectors on a national scale. We aimed quantify fragmentation using various measures and analyze the associations patient outcomes. Methods conducted register-based nationwide cohort study 4.7 million Danish adult citizens. All contacts primary hospitals during 2018 were recorded. Clinical indicators...
Although depression and type 2 diabetes mellitus (DM) may independently increase the risk for dementia, no studies have examined whether dementia among people with comorbid DM is higher than sum of each exposure individually.To examine all-cause persons depression, DM, or both compared neither exposure.We performed a national population-based cohort study 454 532 adults, including 477 133 (19.4%) 223 174 (9.1%) 95 691 (3.9%) both. We included all living Danish citizens 50 years older who...
Multimorbidity is common and associated with poor mental health high mortality. Nevertheless, no studies have evaluated whether may affect the survival of people multimorbidity. We investigated association between perceived stress mortality in multimorbidity by following a population-based cohort 118,410 participants from Danish National Health Survey 2010 for up to 4 years. Information on lifestyle was obtained survey. assessed using nationwide register data 39 conditions identified 4,229...
IMPORTANCEAlthough schizophrenia is associated with several age-related disorders and considerable cognitive impairment, it remains unclear whether the risk of dementia higher among persons compared those without schizophrenia.OBJECTIVE To determine in a large nationwide cohort study up to 18 years follow-up, taking age established factors for into account. DESIGN, SETTING, AND PARTICIPANTSThis population-based more than 2.8 million aged 50 or older used individual data from 6 registers...
Previous small studies have indicated that commonly prescribed drugs may be associated with microscopic colitis (MC). With an increasing incidence of MC, it is important to explore the association between exposure proton pump inhibitors (PPIs), nonsteroidal anti-inflammatory drugs, statins, and selective serotonin reuptake MC in a larger setting.Case-control study based on nationwide Danish registries. The included all patients diagnosis during period 2005 2011. One hundred sex- age-matched...
The objective was to explore patient characteristics and 10-year outcome of sick leave work disability for patients with recent-onset multiple medically unexplained symptoms (MUS) persistent somatoform disorders (SD). Consecutive consulting their family physician (FP) completed a preconsultation questionnaire on mental illness (n= 1785). main problem categorized by the FP after consultation, stratified subsample examined using standardized diagnostic interview 701). Patients were grouped...
Objective. Microscopic colitis (MC) includes two main types: collagenous (CC) and lymphocytic (LC). Previous studies have indicated an increasing incidence, but these mainly been based on regional databases. We found it important to study the epidemiology a comprehensive nationwide cohort. Material methods. studied epidemiological data of MC in Denmark from 2002 2011. The cohort consisted all patients with recorded diagnosis either CC or LC Danish Pathology Register during period. Data...
To compare perinatal and maternal morbidity birth interventions in low-risk women giving two freestanding midwifery units (FMUs) obstetric (OUs).A cohort study with a matched control group.The region of North Jutland, Denmark.839 intending FMU group 839 OU were included at the start care labour. individually chosen to match selected obstetric/socio-economic characteristics women. Analysis was by intention treat.Perinatal interventions.No significant differences observed between groups (Apgar...
It is recognized that higher height and weight are associated with risk of atrial fibrillation or flutter (AF) but it unclear whether AF related to body fat, fat location, lean mass.This article reports the Danish population-based prospective cohort Diet, Cancer Health study conducted among 55,273 men women 50-64 years age at recruitment. The associations between bioelectrical impedance derived measures composition combinations anthropometric distribution an incident record in Registry...
Objective: Structural changes of small resistance arteries occur early in the disease process essential hypertension and predict cardiovascular events previously untreated patients. We investigated whether on-treatment artery structure also identifies patients at elevated risk despite normalization blood pressure (BP). Methods: conducted a long-term follow-up survey 134 moderate-risk with 9–12 months well treated hypertension. All participants underwent subcutaneous biopsies determination...
The loss of a close relative is common event, yet it associated with increased risk serious mental health conditions. No large-scale study has explored up to now the importance bereaved person's relation deceased while accounting for gender and age. We performed nationwide Danish cohort using register information from 1995 through 2013 on four sub-cohorts including all persons aged ≥18 years exposed child, spouse, sibling or parent. identified 1,445,378 persons, each was matched by gender,...
Background Atrial fibrillation ( AF ) and cancer are frequent diseases worldwide. The timewise association between the diagnosis of a subsequent may clarify whether mutual cause exists, also guide clinicians about time windows high risk occurrence. Methods Results We conducted population‐based cohort study among 26 222 men 28 879 women free at baseline based on Danish Diet, Cancer Health study. participants were followed for development (the National Patient Registry) until 2013. used Cox...
Abstract Objective To assess temporal trends in the association between newly diagnosed atrial fibrillation and death. Design Community based cohort study. Setting Framingham Heart Study cohort, 1972-85, 1986-2000, 2001-15 (periods 1-3, respectively), Framingham, MA, USA. Participants with no fibrillation, aged 45-95 each time period, identified (or flutter) during period. Main outcome measures The main was all cause mortality. Hazard ratios for varying mortality were calculated adjustment...
Background and Purpose- It has been suggested that statins increase the risk of intracerebral hemorrhage in individuals with a history stroke, which led to precautionary principle avoiding patients prior hemorrhage. However, such prescribing reticence may be unfounded potentially harmful when considering well-established benefits statins. This study is so far largest explore statin-associated stroke. Methods- We conducted population-based, propensity score-matched cohort using information...
Summary 1. It is well accepted that fish, if abundant, can have a major impact on the zooplankton community structure during summer, which, particularly in eutrophic lakes, may cascade to phytoplankton and ultimately influence water clarity. Fish predation affects mean size of cladocerans grazing pressure phytoplankton. Little is, however, known about role fish winter. 2. We analysed data from 34 lakes studied for 8–9 years divided into three seasons: autumn/spring winter, four lake classes:...
Knowledge of patterns in cancer patients’ health care utilisation around the time diagnosis may guide resource allocation and provide important insights into this groups’ demand for services. The need patients with comorbid conditions far exceeds oncology capacity it is therefore to elucidate role both primary secondary care. aim paper describe use services amongst incident Denmark one year before after diagnosis. present study a national population-based case–control (1:10) registry study....
Hospitalizations for ambulatory care-sensitive conditions (ACSCs) and early rehospitalizations increase health care costs.To determine if individuals with serious mental illnesses (SMIs) (eg, schizophrenia or bipolar disorder) are at increased risk hospitalizations ACSCs, rehospitalization the same another ACSC, within 30 days.Population-based cohort study.A total of 5.9 million Danish persons aged 18 years older between January 1, 1999 December 31, 2013.The Psychiatric Central Register...
Abstract Background Mental stress is associated with higher mortality, but it remains controversial whether the association causal or a consequence of physical disease burden in those high mental load. Understanding causality important when developing targeted interventions. We aimed to estimate effect on mortality by performing ‘natural’ experiment using spousal bereavement as disease-independent stressor. Methods followed population-based matched cohort, including all individuals Denmark...