Yanjun Zhang
A5056760143- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
First Affiliated Hospital of Guangzhou Medical University
2021-2025
State Key Laboratory of Respiratory Disease
2021-2025
Guangzhou Medical University
2021-2025
Virus-specific T cells play essential roles in protection against multiple virus infections, including SARS-CoV and MERS-CoV. While SARS-CoV-2–specific have been identified COVID-19 patients, their role the of SARS-CoV-2–infected mice is not established. Here, using sensitized for infection with SARS-CoV-2 by transduction an adenovirus expressing human receptor (Ad5-hACE2), we cell epitopes recognized CD4+ CD8+ BALB/c C57BL/6 mice. were polyfunctional able to lyse target vivo. Further, type...