A5072732639- Berberine and alkaloids research
- Aquaculture disease management and microbiota
- Ginger and Zingiberaceae research
- Parasite Biology and Host Interactions
- Trace Elements in Health
- Aquaculture Nutrition and Growth
- Medical Research and Treatments
- Biological and pharmacological studies of plants
- Environmental Toxicology and Ecotoxicology
- Natural Compounds in Disease Treatment
- Plant-Microbe Interactions and Immunity
- Rheumatoid Arthritis Research and Therapies
- Bioactive natural compounds
- Fish Biology and Ecology Studies
- Vibrio bacteria research studies
- Mercury impact and mitigation studies
- Mycorrhizal Fungi and Plant Interactions
- Selenium in Biological Systems
- Plant Pathogens and Fungal Diseases
- Phytochemistry and biological activities of Ficus species
- Reproductive biology and impacts on aquatic species
- Cannabis and Cannabinoid Research
- Natural product bioactivities and synthesis
Anhui Normal University
2022-2025
First Affiliated Hospital of Gannan Medical University
2024
China Academy of Chinese Medical Sciences
2023
Rheumatoid arthritis is a chronic immunological disease leading to the progressive bone and joint destruction. Angiogenesis, accompanied by synovial hyperplasia inflammation underlies Delaying or even blocking angiogenesis has emerged as an important target of RA treatment. Natural medicines long history treating RA, numerous reports have suggested that natural strong inhibitory activity on angiogenesis, thereby improving progression RA. could regulate following signaling pathways:...
Background: Berberine has extremely low oral bioavailability, but shows a potent lipid-lowering effect, indicating its potential role in regulating intestinal microbiota, which not been investigated. Methods: In the present study, five experimental diets, control diet (Con), high-lipid (HL), and high-lipid·diets·supplemented with an antibiotic cocktail (HLA), berberine (HLB), or both (HLAB) were fed to zebrafish (Danio rerio) for 30 days. Results: The HLB group showed significantly greater...
Berberine, an isoquinoline alkaloid found in some traditional medicinal plants, such as Berberis vulgaris and Coptis Chinensis , has been considered effective drug treating obesity, hypertension, type-2 diabetes, hyperlipidemia, gout humans animals. It currently certain applications fish nutrition health, mainly because it strong biological pharmacological properties, antioxidative, anti-inflammation, antidiarrheal, analgesic, antimicrobial, anticancer, hepatoprotective, lipid-...
This experiment aimed to investigate the protective effects of berberine on copper-induced liver and gill toxicities in freshwater grouper (Acrossocheilus fasciatus). Fish (initial weight 1.56 ± 0.10 g) were randomly distributed into 12 tanks (80 L, 20 fish per tank) divided four experimental groups: The control group, exposed 0.02 mg/L Cu2+ (Cu group), fed 100 mg/kg (BBR100 400 (BBR400 group). After a 30-day experiment, results showed that significantly increased activities catalase...
Berberine has growth-promoting and lipid-lowering effects potentially through the regulation of intestinal microbiota bile acid profiles. This experiment aimed to investigate effect dietary berberine on microbiota-bile acid-farnesoid X receptor (FXR) axis in yellow catfish (Pelteobagrus fulvidraco). Fish (initial weight: 1.32 ± 0.26 g) were fed a control diet or supplemented with 100 mg/kg (BBR100) 400 (BBR400) for 60 days. The BBR400 group showed significant improvements growth performance,...
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Berberine has been shown to have a potent lipid-lowering effect in fish, potentially through the regulation of intestinal microbiota composition and bile acids profile. In this study, yellow catfish (Pelteobagrus fulvidraco) (initial weight: 1.32 ± 0.26 g) were fed either control diet or supplemented with 100 mg/kg 400 berberine (BBR100 BBR400) for 60 days. The BBR400 group showed significant improvements growth performance, hepatic superoxide dismutase (SOD) catalase (CAT) activities,...
Background: Diabetic nephropathy (DN) was one of the most significant microvascular complications associated with diabetes mellitus. Qingxin Lianzi Yin Decoction (QXLZY) a traditional Chinese classical formula, suitable for chronic urinary system diseases, and had good clinical efficacy in neurasthenia early DN. This study aimed to establish index component content determination method QXLZY explore mechanism on DN by metabolomics network pharmacology studies.Methods: The methods were...