A5032752205- Gut microbiota and health
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Microbial Metabolites in Food Biotechnology
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Antioxidant Activity and Oxidative Stress
- Pomegranate: compositions and health benefits
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Food composition and properties
- Biochemical Analysis and Sensing Techniques
- Breastfeeding Practices and Influences
- Air Quality and Health Impacts
- Medicinal Plant Extracts Effects
- Clostridium difficile and Clostridium perfringens research
- Healthcare and Venom Research
- Medical and Biological Ozone Research
- Tryptophan and brain disorders
- Air Quality Monitoring and Forecasting
- Metabolomics and Mass Spectrometry Studies
- GABA and Rice Research
- Stress Responses and Cortisol
- Climate Change and Health Impacts
- Insect and Pesticide Research
Plant & Food Research
2016-2023
Palmerston North Hospital
2021
Translational Research Institute
2016
Queensland University of Technology
2016
Abstract Bioactive compounds including anthocyanins and other polyphenols are associated with reduced lung inflammation improved function in asthma diseases. This study investigated the effects of a Boysenberry apple juice concentrate, high cyanidin glycosides, ellagitannins, chlorogenic acid, on mouse model allergic airways inflammation. Male C57BL/6J mice were orally gavaged 2.5 mg/kg total (TAC) from BerriQi® concentrate (0.2 human equivalent dose) or water control 1 hr before an acute...
Human breastmilk components, the microbiota and immune modulatory proteins have vital roles in infant gut development. In a population of breastfeeding women (n = 78) different ethnicities (Asian, Māori Pacific Island, New Zealand European) their infants living Manawatu–Wanganui region Zealand, we examined breast milk, fecal mothers infants. Breast milk samples were collected over one-week period during six to eight weeks postpartum. differed between ethnic groups. However, these differences...
The aim of this study was to test the hypothesis that consuming manuka honey, which contains antimicrobial methylglyoxal, may affect gut microbiota. We undertook a mouse feeding investigate whether dietary honey supplementation altered microbial numbers and their production organic acid products from carbohydrate fermentation, are markers microbiota function. caecum C57BL/6 mice fed diet supplemented with UMF® 20+ at 2.2 g/kg animal did not show any significantly changed concentrations short...
Goat and cow milk differed in their effects on gut microbiota composition metabolism following antibiotic-induced dysbiosis rats.
The relationship between the microbiota profile and exposure to stress is not well understood. Therefore, we used a rat model of unpredictable chronic mild (UCMS) investigate this relationship. Depressive-like behaviors were measured in Female Sprague Dawley rats using sucrose preference test Porsolt swim test. Anxiety-like with light-dark box Fecal corticosterone, cecal (composition organic acids), plasma gut permeability (lipopolysaccharide-binding protein, LBP) inflammation (12 cytokines)...
Increased global industrialization has increased air pollution resulting in 3 million annual deaths globally. Air pollutants could have different health effects, so specific models to identify the immune effects are needed. The aim of this study was determine and lung function acute exposure two sources using a mouse model. Three intranasal challenges with either urban dust or diesel particulate matter resulted significant (P < 0.001) cell infiltration into lung, which mostly because an...
Non-sugar components of kiwifruit reduce the amplitude glycaemic response to co-consumed cereal starch. We determined relative contribution different non-sugar this anti-glycaemic effect. Healthy participants (n = 9) ingested equal carbohydrate meals containing 20 g starch as wheat biscuit (WB, 30 g), and sugar equivalent two (KFsug, 20.4 either intrinsic or added glucose, fructose sucrose (2:2:1). The were WB+KFsug (control, no components), WB + whole pulp (WB+KF), neutralised (WB+KFneut),...
The benefits of lowering blood pressure (BP) are well established for the prevention cardiovascular disease. While there a number pharmaceuticals available BP, is considerable interest in using dietary modifications, lifestyle and behaviour changes as alternative strategies. Kukoamines, caffeic acid derivatives polyamines present solanaceous plants, have been reported to reduce BP. We investigated effect orally administered synthetic kukoamine A on BP Spontaneously Hypertensive Rat (SHR)...
People with pre-diabetes may be reluctant to add fruit their diets due concerns around sugars. Our objective was measure outcomes associated potential adverse effects of ingesting sugars while assessing metabolic benefits from eating nutrient-rich kiwifruit. Thirty-four people were randomized receive two kiwifruit or 250 mL bottled water per day for 12-weeks; withdrew. The primary between-group differences glycated haemoglobin (HbA1c) and plasma vitamin C concentration. Secondary included...
Abstract Bioactive compounds such as anthocyanins, proanthocyanins and other polyphenols are found in a wide variety of fruits vegetables, consumption these have been associated with reduced lung inflammation improved function asthma diseases. We investigated whether combination Boysenberry apple juice, BerriQi ® juice concentrate, could reduce the allergic airways asthma. characterised polyphenolic components concentrate identified main cyanidin glycosides, ellagitannins, chlorogenic acid....
Air pollution is estimated to cause 7 million annual deaths globally. Our aim was determine if dietary propolis consumption could prevent the immune and functional damage in a mouse model of acute urban dust exposure. Female C57BL/6J mice were challenged three times with intranasal over seven days which significantly increased proinflammatory cytokines cells lung 24 h post final challenge. Dietary New Zealand (2%) gamma cyclodextrin supplementation reduced dust-induced TNFα, IL-4, IL-6...
Kiwifruit contain many components, some considered beneficial, such as vitamins, phytochemicals and dietary fibre, others potentially harmful, fructose glucose in fruit sugars. In a 6-week, randomised, crossover study aimed at exploring the net effects of daily consumption kiwifruit, 23 healthy participants consumed two Actinidia chinensis var. ‘Zesy002’ (marketed Zespri™ SunGold™ Kiwifruit) per day part their customary diet (intervention) or without kiwifruit (control) for 6 weeks...