Production of infant formulas involves high temperature processing for microbiological safety. However, heat processes generate Advanced Glycation End-products (AGEs), including Nε-carboxymethyllysine (CML) formed between lysine and lactose. Formulas manufactured from cow or goat milk, with without whey adjustment, hydrolysates proteins, were tested CML levels using a commercially available ELISA kit. concentrations ranged 2 to 210 µg/g protein in containing intact proteins. Median up 3-fold...

Cellular responses of a group cattle immunized subcutaneously with low dose Mycobacterium bovis bacille Calmette-Guerin vaccine (BCG) were measured in vitro and compared nonimmunized control animals. PBMC taken from animals proliferated produced IFN-gamma the presence M. BCG culture filtrate proteins. The addition to BCG-infected autologous macrophages also resulted secretion IFN-gamma. In contrast, comparatively over period study. experiments study interaction non-adherent lymphocytes...

Fortified milk drinks are predominantly manufactured from bovine (cow) sources. Alternative formulations include those prepared with hydrolysed proteins or alternate bovidae species, such as caprine (goat) milk. Currently, there is little data on protein digestive and metabolic responses following ingestion of fortified drinks. To examine the to commercially-available milks, young adults (n = 15 males: females), in a randomised sequence, ingested isonitrogenous quantities whole cow-protein...

Goat and cow milk share similar protein lipid content, yet goat forms softer curds during stomach digestion.

Nitric oxide (NO) production was evaluated in macrophages isolated from Mycobacterium bovis bacille Calmette‐Guérin (BCG)‐immunized, and control non‐immunized, cattle. Incubation of M. BCG‐infected with recombinant bovine IFN‐γ led to increased nitrite levels culture supernatants. It also demonstrated that NO by autologous a linear relationship the number antigen‐specific lymphocytes added cultures. The elevated were associated secretion. Treatment cultures inhibitor, N ‐monomethyl l...

Adjustment of protein content in milk formulations modifies and energy levels, ensures amino acid intake affects satiety. The shift from the natural whey:casein ratio ~20:80 animal is oftentimes done to reflect 60:40 human milk. Studies show that 20:80 versus milks differently affect glucose metabolism hormone release; these data parallel model findings. It unknown whether adjustment appetite brain processes related food intake. In this set studies, we focused on impact vs. feeding-related...

Goat and cow milk differed in their effects on gut microbiota composition metabolism following antibiotic-induced dysbiosis rats.

Goat's (GM) and cow's milk (CM) are dietary alternatives with select health benefits shown in human animal studies. Surprisingly, no systematic analysis of palatability or preference for GM vs. CM has been performed to date. Here, we present a comprehensive investigation short-term intake profiles laboratory mice rats. We studied consumption no-choice choice scenarios, including meal microstructure, by using isocaloric milks milk-enriched solid diets. Feeding results accompanied qPCR data...

Objectives: Our goals were to determine whether a bovine milk product containing anti– Candida albicans immunoglobulin A antibodies (“immune milk”) could reduce the adherence of C voice prosthesis silicone in vitro, and administration colonization damage vivo. Methods: An vitro assay attachment was developed with radiolabeled albicans. pilot crossover vivo trial, over 3 periods months, also undertaken for 4 patients prostheses, comparing daily administrations immune control product. The...

The natural 20:80 whey:casein ratio in cow's milk (CM) for adults and infants is adjusted to reflect the 60:40 of human milk, but feeding metabolic consequences this adjustment have been understudied. In adult subjects, CM differently affects glucose metabolism hormone release than CM. laboratory animals, whey-adapted goat's consumed larger quantities. It unknown whether whey enhancement would similar on appetite it affect feeding-relevant brain regulatory mechanisms. set studies utilizing...

A free essential amino acid, L-tryptophan (TRP), administered through a diet or directly into the gut, decreases food intake by engaging neural mechanisms. The ability of intragastric TRP to cross general circulation and blood-brain barrier, at least partly underlies hypophagia. It is unclear although, whether TRP's anorexigenic effects accompanying processes occur in absence initial action on gut mucosa. Here, we addressed this issue using fundamental approach examining intraperitoneally...

Atopic dermatitis (AD) is a debilitating disease that disproportionately affects infants and young children considered the first step of atopic march—the age-related progression allergic disease. Consequently, there an urgent unmet need to elucidate root causes AD evaluate potential prevention mechanisms.

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Size: Aa Line Spacing:  Column Width:  Background: Open AccessAbstract Animal Model of Antibiotic Induced Gut Microbiota Dysbiosis † by Christine A. Butts 1,*, Gunaranjan Paturi 2, Halina Stoklosinski 1, Sheridan Martell Duncan Hedderley 1 and Elizabeth Carpenter 3 New Zealand Institute for Plant Food Research Ltd., Palmerston North 4474, 2 Research, Auckland 1025, Dairy Goat Co-operative (NZ) Hamilton 3240, *...

Culture filtrates derived from a Mycobacterium bovis cosmid library in smegmatis were screened for T cell antigens. Recognition and reactivity measured by the levels of lymphocyte proliferation gamma interferon (IFN-gamma) produced when culture incubated with peripheral blood mononuclear cells (PBMC) taken cattle immunised M. BCG. The screening system was optimised to distinguish between secreted antigens normal proteins. From ten screened, two identified that induced IFN-gamma production....