- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Lipoproteins and Cardiovascular Health
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Research
- Cancer, Lipids, and Metabolism
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiac and Coronary Surgery Techniques
- Heart rate and cardiovascular health
- Lung Cancer Diagnosis and Treatment
- Autopsy Techniques and Outcomes
- Elasticity and Material Modeling
- Regional Development and Management Studies
- Vitamin D Research Studies
- Medical Imaging and Pathology Studies
- IL-33, ST2, and ILC Pathways
- Retinal Diseases and Treatments
- Advanced Radiotherapy Techniques
- Healthcare and Venom Research
University of Kragujevac
2005-2024
Clinical Centre of Kragujevac
2011-2023
University of Belgrade
2022
The aim of this study was to investigate histamine blood concentration in subjects suffering from different types ischemic heart diseases during the period eight days. Our results showed that level associated with diseases. all investigated patients significantly higher when compared control (44.87 ± 1.09 ng mL(-1)), indicating increase release coronary In ACS-UA and ACS-STEMI, second day peak occurs (90.85 6.34 mL(-1) 121.7 mL(-1), resp.) probably as reperfusion event. Furthermore, our data...
Background and aim: N terminal-proB-type natriuretic peptide (NT-proBNP) is synthesised secreted from the ventricularmyocardium. This marker known to be elevated in patients with acute coronary syndromes (ACS). We evaluated NT-proBNP asa significant diagnostic an important independent predictor of short-term mortality (one month) ACS. Methods: cardiac troponin I (cTI) were assessed 134 consecutive (median age 66 years, 73% male)hospitalised for ACS a cardiological university department. The...
Aim: We aimed to single out admission predictors of acute respiratory distress syndrome (ARDS) in hospitalized COVID-19 patients and investigate the role bioelectrical impedance (BIA) measurements ARDS development. Method: An observational, prospective cohort study was conducted on 407 consecutive at University Clinical Center Kragujevac between September 2021 March 2022. Patients were followed during hospitalization, observed as a primary endpoint. Body composition assessed using BMI, body...
Introduction: The use of β-blockers in the treatment patients with coronary heart disease is associated a decrease frequency angina pectoris and mortality patients. Due to severity previous cardiovascular interventions, many artery (CAD) dual antiplatelet therapy achieve greater inhibition platelet aggregation. influence on aggregation using not well understood. Objective: To examine effect different therapy. Methodology: study included 331 who were treated at Department Cardiology, Clinical...
Published data regarding the impact of obesity on COVID-19 outcomes are inconsistent. However, in most studies, body composition was assessed using mass index (BMI) alone, thus neglecting presence and distribution adipose tissue. Therefore, we aimed to investigate visceral fat outcomes.Observational, prospective cohort study included 216 consecutive patients hospitalized at University Clinical Center Kragujevac (Serbia) from October December 2021. Body BMI, percentage (%BF), (VF) via...
Background: Early prediction of COVID-19 patients’ mortality risk may be beneficial in adequate triage and assessment. Therefore, we aimed to single out the independent morality predictors hospitalized patients among parameters available on hospital admission. Methods: An observational, retrospective−prospective cohort study was conducted 703 consecutive University Clinical Center Kragujevac between September December 2021. Patients were followed during hospitalization, in-hospital observed...
Hyperglicemia is common in patients with ST-elevation myocardial infarction (STEMI) and associated high risk of mortality morbidity. Relationship between admission plasma glucose (APG) levels diabetic nondiabetic STEMI needs further investigation. The aim this study was to analyse the short- long-term prognostic significance APG without diabetes.This included 115 STEMI, 86 (74.8%) 29 (25.2%) dibaetic patients, which we performed a prospective analysis relationship mortality.Comparison (8.32...
The purpose of this study is to reveal the participation different regulatory cytokines within process pseudoexfoliation (PEX).Our included 140 patients referred cataract surgery with early and late stage syndrome (XFS) or glaucoma (XFG). Humor serum levels cytokines: transforming growth factor beta (TGF-β), platelet-derived (PDGF), epidermal (EGF), insulin-like (IGF), IL-8 interferon-inducible T cell alpha chemoattractant (ITAC) were measured in a sample using high sensitivity enzyme-linked...
Coronary artery spasm is sometimes an unrecognized cause of myocardial ischemia. Myocardial ischemia not always a product fixed stenosis; it can also be induced by dynamic, transient stenosis. The angiogram represents the current state vasculature at time examination and absence stenosis does mean disease absence. We present case right coronary that caused non-ST elevation infarction arrhythmias was again in cath lab due to vasovagal reaction.
Fractional flow reserve (FFR) is the gold standard for functional assessment of coronary arteries. The aim this study was to evaluate relation between angiography, QCA and FFR in borderline lesions on collateral donor In addition, compared with angiographic appearance collaterals infarction-related arteries echocardiographically assessed viability infarct related LV wall. 60 patients previous IM occluded IRA, stenosis (30-70% DS) artery performed. We have not found statistically significant...
Abstract Spontaneous coronary artery dissection (SCAD) is an uncommon yet increasingly recognized cause of acute syndrome (ACS), particularly in young to middle-aged women. This multicentric, prospective nation-wide registry aimed elucidate the demographic characteristics, clinical presentation, management strategies, and outcomes patients with SCAD. A total 95 SCAD were enrolled 10 centers, females constituting 81% cohort, average age 49.7±11.9 years. Among traditional risk factors, prior...
Despite the wide usage of exercise ECG tests and Duke Treadmill Score (DTS) in clinical practice, no comparison between this scoring system Fractional Flow Reserve (FFR) has yet been made, particularly cases angiographically verified borderline lesions. Thirty patients with single coronary lesions assessed stenosis (between 30-70%) previously calculated intermediate values DTS -10 to +4 were examined using FFR. Adequate specificity sensitivity (0.769 0.556, respectively) a more narrow range...
Acute coronary syndrome, as unstable form of ischaemic heart disease, beside clinical presentation and electrocardiographic abnormalities, is characterized by increased value troponin one cardiospecific enzimes. Although a high specific sensitive indicator acute any muscle injury may induce its increasing, so there are some other diseases with the value.We presented female patient chest pain, admitted because suspicioun syndrome. Performed coronarography excluded ischemic disease....
Background/Aim. Liver damage, with potentially serious consequences, is not uncommon in hospitalized cardiac patients. The aim of our study was to determine the risk factor profile for liver damage patients from a deterioration their acute or chronic illness. Methods. had observational case-control design retrospective data collections medical files adult tertiary health care center. cases (n = 140) were subjects novel injury (which emerged during hospital stay) and three control matched...
Abstract We present the case of patient with ST elevation myocardial infarction in cardiogenic shock primary percutaneous coronary intervention Left anterior descending artery and main staged complex procedure on descending/Diagonal branch bifurcation Culotte manner. This shows that “the simpler, better” approach only infarct related revascularization may be applied acute patients optimal clinical hemodynamic response intra-aortic balloon pump. But, complete should done later, a control...
Purpose: To evaluate prognostic value of heart rate in patients with acute myocardial infarction. Patients and method: Our retrospective study included 105 were divided two groups: I group adverse outcome (MACE (myocardial infarction, unstable angina, cardiovascular death, revascularisation, fatal/nonfatal cerebrovascular accident, aortic event) failure requiring hospitalization) during one month after infarction II without outcome. We observed the presence following factors: heritage, at...
Introduction. Myocardial infarction (MI) is characterized by a critical myocardial ischemia followed an irreversible cell damage or death. Case report. We presented two similar clinical cases with the ST segment elevation (STEMI) diagnosis due to prolonged coronary artery spasm, but different treatment options basic patophysiological supstrates and presentations. Conclusion. Coronary spasm very complex pathophysiological entity medication therapy management. Although percutaneous...
Background: Coronary artery disease is the most common cause of death in a modern world.This dictates development network Catheterization laboratories without cardiosurgical capabilities. Aim:We postulate that valuable tool decision process on myocardial revascularization fractional flow reserve (FFR), especially when we deal with borderline coronary lesions. Material and Methods:A total 72 patients 94 intermediate stenosis (30%-70% diameter reduction) were included this study.We tested FFR...
Background: Ischemic heart disease (IHD) is a most common manifestation of generalised atherosclerosis. Hyperlipidemia one the significant risk factors causing Becouse this, statin therapy ²guideline² in hyperlipoproteinemia. Aim: The aim this study was to show hypolipemic effect statins. Material and Methods: research included 74 patients with hyperlipoproteinemia type II III, (59 patients) or without (15) coronary diagnosis. All have been treated In all patients, we analizing statins...