Jan Müller

ORCID: 0000-0002-7530-2025
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Cardiovascular Function and Risk Factors
  • German Economic Analysis & Policies
  • Cardiovascular and exercise physiology
  • Cardiovascular Effects of Exercise
  • Coronary Artery Anomalies
  • Pulmonary Hypertension Research and Treatments
  • Cardiovascular Health and Disease Prevention
  • Blood Pressure and Hypertension Studies
  • Heart Rate Variability and Autonomic Control
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Issues in Pregnancy
  • Physical Activity and Health
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Childhood Cancer Survivors' Quality of Life
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Obesity, Physical Activity, Diet
  • Cardiac Arrest and Resuscitation
  • Heart Failure Treatment and Management
  • Ecology, Conservation, and Geographical Studies
  • Regional Development and Innovation
  • German Literature and Culture Studies
  • Cardiac Imaging and Diagnostics

Technical University of Munich
2015-2024

Deutsches Herzzentrum München
2015-2024

RWTH Aachen University
2023

University of Bonn
2023

LVR-Klinik Köln
2023

Johannes Gutenberg University Mainz
2023

German Centre for Cardiovascular Research
2022

Brno University of Technology
2021-2022

University of Applied Sciences and Arts Hildesheim/Holzminden/Göttingen
2022

BIA Separations (Slovenia)
2022

Controversy exists about the timing of initiation parenteral nutrition in critically ill adults whom caloric targets cannot be met by enteral alone.In this randomized, multicenter trial, we compared early (European guidelines) with late (American and Canadian intensive care unit (ICU) to supplement insufficient nutrition. In 2312 patients, was initiated within 48 hours after ICU admission (early-initiation group), whereas 2328 not before day 8 (late-initiation group). A protocol for applied...

10.1056/nejmoa1102662 article EN New England Journal of Medicine 2011-06-30

Casaer, Michael P.; Mesotten, Dieter; Hermans, Greet; Wouters, Pieter J.; Schetz, Miet; Meyfroidt, Geert; van Cromphaut, Sophie; Ingels, Catherine; Meersseman, Philippe; Muller, Jan; Vlasselaers, Dirk; Debaveye, Yves; Desmet, Lars; Dubois, Jasperina; Assche, Aime; Vanderheyden, Simon; Wilmer, Alexander; den Berghe, Greet Author Information

10.1097/01.sa.0000412381.92989.8e article EN Survey of Anesthesiology 2012-03-24

Randomized, controlled trials have shown both benefit and harm from tight blood-glucose control in patients the intensive care unit (ICU). Variation use of early parenteral nutrition insulin-induced severe hypoglycemia might explain this inconsistency. Download a PDF Research Summary. We randomly assigned patients, on ICU admission, to liberal glucose (insulin initiated only when level was >215 mg per deciliter [>11.9 mmol liter]) or (blood-glucose targeted with LOGIC-Insulin algorithm at 80...

10.1056/nejmoa2304855 article EN New England Journal of Medicine 2023-09-27

The effects and safety of using oral nifedipine 10-20 mg as acute antihypertensive treatment were studied in a single-blind placebo-controlled study 25 consecutive patients with very high blood pressure requiring emergency reduction. In addition the effect this on cerebral flow was investigated xenon-133 10 randomly allocated to receive or intravenous clonidine. Whereas placebo did not alter pressure, significantly reduced systolic diastolic pressures all (from 221 +/- 22/126 14 mm Hg 152...

10.1136/bmj.286.6358.19 article EN BMJ 1983-01-01

AimsPatients with congenital heart disease usually show diminished exercise capacity and quality of life. However, there is only little information about daily activity, a marker for lifestyle, capacity, the prevention arteriosclerosis. This study investigated life, their interaction univentricular physiology after total cavopulmonary connection (TCPC).

10.1093/eurheartj/ehp305 article EN European Heart Journal 2009-08-18

Nowadays Internet routing attacks remain practically effective as existing countermeasures either fail to provide protection guarantees or are not easily deployable.Blockchain systems particularly vulnerable such they rely on Internet-wide communications reach consensus.In particular, Bitcoin-the most widely-used cryptocurrency-can be split in half by any AS-level adversary using BGP hijacking.In this paper, we present SABRE, a secure and scalable Bitcoin relay network which relays blocks...

10.14722/ndss.2019.23252 article EN 2019-01-01

Irrespective of their cardiovascular findings, quality life in patients with congenital heart disease (CHD) is good or even superior to that healthy controls. The sense coherence (SOC), a psychological resource focuses on factors support human health and well-being, was suggested act as potential pathway for maintaining improving independently from the status.From April 2010 May 2011, we consecutively included 546 young adults (236 female, median age 26.9 years, aged 16 71 years) various CHD...

10.1177/2047487313481753 article EN European Journal of Preventive Cardiology 2013-03-04

Objectives Improved treatments for patients with congenital heart disease (CHD) have led to a growing interest in long-term functional outcomes such as health-related quality of life (HRQoL). Studies on HRQoL children CHD contradicting results. Therefore, we compared that current healthy peers and stratify cases by severity diagnostic subgroups. Methods We included 514 (191 girls) aged 7–17 (12.9±3.1) years who were recruited at our institution between July 2014 May 2017. The self-reported...

10.1136/archdischild-2017-314211 article EN Archives of Disease in Childhood 2018-03-29

Background: Survivors of childhood cancer are at risk for anthracycline- and/or radiotherapy-induced cardiotoxicity. Aims: The aim this study was to assess clinical, laboratory, and imaging parameters subclinical cardiovascular disease in survivors. Methods: Patients underwent cardiopulmonary exercise test (CPET), laboratory testing, transthoracic echocardiography (TTE) with tissue doppler (TDI) speckle tracking. A subset patients also magnetic resonance (CMR). Findings were correlated...

10.3389/fped.2020.00123 article EN cc-by Frontiers in Pediatrics 2020-03-31

Abstract Background Extreme weather events and natural disasters such as floods can cause severe damage impacts on catchment systems covering well urban, industrial or agricultural areas. Thus, often lead to the acute unusual release of organic pollutants, remobilization legacy contaminations old burdens. Floodplains are then major relevance for accumulation pollutants. Accordingly, various floodplains distributed throughout course Rur River were sampled immediately after two flood in...

10.1186/s12302-023-00717-4 article EN cc-by Environmental Sciences Europe 2023-03-06

Aim The Fontan circulation is highly dependent on ventilation, improving pulmonary blood flow and cardiac output. A reduced ventilatory function reported in these patients. extent of this impairment its relation to exercise capacity quality life unknown objective study. Methods This multicenter retrospective/cross-sectional study included 232 patients (140 females, age 25.6 ± 10.8 years) after palliation (19.8% atrioventricular connection; 20.3% atriopulmonary 59.9% total cavopulmonary...

10.1111/chd.12694 article EN Congenital Heart Disease 2018-10-30

Objective: Physical activity (PA) is associated with multiple beneficial health outcomes. Unfortunately, current studies report an alarming decrease of PA throughout all age groups. This study aims to assess general feasibility and levels kindergarten primary school children wearable technology specifically manufactured for young children. Patients methods: From April 2017 August a total 59 (7.1 ± 1.7 years, 34 girls) recorded their seven consecutive day wearing bracelet (Garmin vivofit jr)....

10.3389/fped.2018.00005 article EN cc-by Frontiers in Pediatrics 2018-01-25
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