A5041994286- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Hydrogels: synthesis, properties, applications
- Advanced Polymer Synthesis and Characterization
- Nanoparticle-Based Drug Delivery
- Additive Manufacturing and 3D Printing Technologies
- Advanced Drug Delivery Systems
- Polymer composites and self-healing
- Characterization and Applications of Magnetic Nanoparticles
- Advanced Sensor and Energy Harvesting Materials
- Polymer Surface Interaction Studies
- Natural Fiber Reinforced Composites
- Bone Tissue Engineering Materials
- Adsorption and biosorption for pollutant removal
- Photopolymerization techniques and applications
- Agricultural and Food Sciences
- Surfactants and Colloidal Systems
- Dendrimers and Hyperbranched Polymers
- Advanced Materials and Mechanics
- Biodiesel Production and Applications
- Polysaccharides Composition and Applications
- Analytical Methods in Pharmaceuticals
- Science and Education Research
- Flame retardant materials and properties
- Microencapsulation and Drying Processes
Universidade de São Paulo
2016-2025
Recaltech (Brazil)
2024
Biotech (Brazil)
2024
École d'Ingénieurs en Chimie et Sciences du Numérique
2010-2015
Automation and Process Engineering Laboratory
2010-2015
Despite the resistance of triple-negative breast cancer (TNBC) to targeted hormone therapy, discovery azobenzene combretastatin A4 (Azo-CA4) provides therapeutic opportunities for TNBC. Here, Azo-CA4 was loaded in upconverting nanocarriers that could convert near-infrared (NIR) light UV activate Azo-CA4. Upon irradiation, Azo-CA4-loaded significantly reduced viability TNBC cells via both apoptosis and ferroptosis. The former induced by photoisomerization Azo-CA4, accompanied microtubule...
Abstract This study aimed to evaluate the effect of pullulan (Pull) on a renewable polyurethane sponge‐like scaffold synthesized from Pull mixture with castor oil‐based polyol and prepolymer using situ foaming method. The contents are 5, 10, 20 wt.%. samples were evaluated by optical microscopy (OM), scanning electron (SEM), density, Fourier transform infrared spectroscopy (FTIR), contact angle, Thermogravimetry, X‐ray diffraction analysis (XRD), compression strength test, respectively. FTIR...
Abstract The goal of this study was to develop a new route prepare thermally responsive polymer nanogels. Poly( N ‐vinylcaprolactam) nanogels were prepared via inverse miniemulsion polymerization (W/O) at 70 °C using n ‐hexadecane as nonpolar continuous phase, potassium persulfate an initiator, and N,N ′‐methylenebisacrylamide crosslinker. Sorbitan monooleate (Span 80) used surfactant its influence on the kinetics colloidal characteristics principally investigated. It observed that addition...
Chemical modification of natural polymers has been commonly employed for the development new bio-based materials, aiming at adjusting specific properties such as solubility, biodegradability, thermal stability and mechanical behavior. Among all polymers, polysaccharides are promising in which processability bioreactivity make them suitable biomedical applications. In this context, work describes synthesis characterization a novel amphiphilic pullulan-g-poly(ε-caprolactone) (Pull-g-PCL) graft...
Abstract The kinetics of the solution free radical polymerization N ‐vinylcaprolactam, in 1,4‐dioxane and under various conditions was studied. Azobisisobutyronitrile 3‐mercaptopropionic acid were used as initiator chain transfer agent (CTA), respectively. influence monomer concentrations temperature on rate polymerizations ( R p ) investigated. In general, high conversions obtained. order with respect to consistent classical kinetic equation, while greater than unity. overall activation...
Well-defined amphiphilic, biocompatible and partially biodegradable, thermo-responsive poly(N-vinylcaprolactam)-b-poly(ε-caprolactone) (PNVCL-b-PCL) block copolymers were synthesized by combining reversible addition-fragmentation chain transfer (RAFT) ring-opening polymerizations (ROP). Poly(N-vinylcaprolactam) containing xanthate hydroxyl end groups (X-PNVCL-OH) was first RAFT/macromolecular design the interchange of xanthates (RAFT/MADIX) polymerization NVCL mediated a agent function. The...
Abstract The development of new biodegradable composites with superior properties is an attractive approach to develop environmentally friendly materials potential applications. In this work, we prepared and characterized PHB filaments different concentrations ZnO particles (from 0.5 up 16 wt%) evaluate mixture's effect on the physico‐chemical, thermal properties, morphological biofilament characteristics. FTIR Raman results indicated a possible chemical interaction between PHB, altering...
Poly(N-vinylcaprolactam) (PNVCL) and poly(N-vinylcaprolactam-co-acrylic acid) (poly(NVCL-co-AA)) were synthesized by solution-free radical polymerization displayed thermo-responsive behavior, with lower critical solution temperatures (LCSTs) of 35 °C 39 °C, respectively. The incorporation AA unities made the poly(NVCL-co-AA) sensitive to both pH temperature. They exploited in this work preparing microparticles loaded ketoprofen via spray-drying modulate drug release rate changing or...
Biodegradable and biocompatible copolymers have been often studied for the development of biomaterials drug delivery systems. In this context, work reports synthesis characterization a novel pullulan-g-poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (Pull-g-PHBHV) graft copolymer using click chemistry. Well-defined functional pullulan backbones containing azide groups (PullN3) previously prepared by our group were successfully used purpose propargyl-terminated...