A5048282910- Acupuncture Treatment Research Studies
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Botulinum Toxin and Related Neurological Disorders
- Complementary and Alternative Medicine Studies
- Stroke Rehabilitation and Recovery
- Gut microbiota and health
- Pain Mechanisms and Treatments
- Dementia and Cognitive Impairment Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroscience and Neuropharmacology Research
- Diet and metabolism studies
- Insect and Pesticide Research
- Cerebrovascular and genetic disorders
- Pain Management and Placebo Effect
- Medicinal Plants and Bioactive Compounds
- Heart Rate Variability and Autonomic Control
- Tryptophan and brain disorders
- Bee Products Chemical Analysis
- Cholinesterase and Neurodegenerative Diseases
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2021-2024
Beijing University of Chinese Medicine
2016-2018
Beijing Hospital of Traditional Chinese Medicine
2017-2018
Capital Medical University
2017-2018
Background Numerous pertinent investigations have demonstrated a correlation between gut microflora (GM) and the occurrence of dementia. However, causal connection GM dementia its subtypes has not yet been clarified. Objective To explore association dementia, including subtypes, two-sample Mendelian randomization (TSMR) analysis was used. Methods Our data comes from Genome-Wide Association Study (GWAS). The principal approach employed for study inverse-variance weighted method, supplemented...
Background and Purpose— Emerging evidence suggests that acupuncture could improve cognitive impairment in vascular dementia by enhancing synaptic plasticity the hippocampus. The purpose of this study is to investigate whether dopamine, a key mediator plasticity, involved improvement. Methods— Vascular model was established bilateral common carotid arteries occlusion male Wistar rats. Three days after operation, animals received treatment for 2 weeks, once daily. D1/D5 receptors antagonist...
Summary Aims Acupuncture has been reported to affect vascular dementia through a variety of molecular mechanisms. An isobaric tag for relative and absolute quantification (iTRAQ) with high‐resolution liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) analyses makes it possible attain global profile proteins. Hence, we used an iTRAQ‐LC‐MS/MS strategy unravel the underlying mechanism acupuncture. Methods Wistar rats were subjected bilateral common carotid occlusion. was intervened 2...
The sympathetic nervous system, via epinephrine and norepinephrine, regulates β -adrenergic receptor ( -AR) expression, renal activation causes sustained increases in blood pressure by enhanced renin release. In this study, we aim to investigate the effect underlying mechanism of acupuncture at Taichong (LR3) on activity spontaneously hypertensive rats. Unanesthetized rats were subject daily for 2 weeks. Mean (MBP) heart rate variability (HRV) monitored days 0, 7, 14 radiotelemetry. After...
Alteration of dopamine (DA) and noradrenaline (NA) contributes to cognitive function. Acupuncture has been shown affect DA NA in chronic cerebral hypoperfusion (CCH) rats. However, the effect acupuncture on DA- β -hydroxylase (DBH), biosynthetic enzyme NA, remains unknown. In CCH rats we established by bilateral common carotid artery occlusion (two-vessel occlusion, 2VO) treated them with acupuncture. displayed beneficial effects hippocampus-dependent memory impairments, including nonspatial...
Introduction Limb motor dysfunction is one of the challenges in rehabilitation after cerebral ischemic stroke (CIS) and greatly affects quality life patients. This study aims to investigate central mechanisms curative effect with multimodal magnetic resonance imaging (MRI), which will provide additional evidence support application Xingnao Kaiqiao (XNKQ) acupuncture. Methods analysis trial a randomized controlled trial. Patients who meet criteria be recruited randomly divided into 2 groups....
To observe the effects of Xingnao Kaiqiao (regaining consciousness and opening orifices) acupuncture on hemorrhagic transformation limb motor function after intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) in stroke patients.A total 130 patients rt-PA thrombolytic were divided into an group (58 cases, 1 case dropped off) a non-acupuncture (72 7 cases according to whether they received treatment. Propensity score matching (PSM) was used match each group, 38...