Irene Krämer

ORCID: 0000-0002-7576-3665
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About
Contact & Profiles
Research Areas
  • Pharmaceutical studies and practices
  • Safe Handling of Antineoplastic Drugs
  • Inhalation and Respiratory Drug Delivery
  • Biosimilars and Bioanalytical Methods
  • Muscle metabolism and nutrition
  • Nutrition and Health in Aging
  • Intravenous Infusion Technology and Safety
  • Antibiotics Pharmacokinetics and Efficacy
  • Chemotherapy-related skin toxicity
  • Neutropenia and Cancer Infections
  • Pharmaceutical Practices and Patient Outcomes
  • Medication Adherence and Compliance
  • Linguistic research and analysis
  • Cancer Treatment and Pharmacology
  • Medical Device Sterilization and Disinfection
  • Protein purification and stability
  • Media Studies and Communication
  • Digital Innovation in Industries
  • Structural and Chemical Analysis of Organic and Inorganic Compounds
  • Cystic Fibrosis Research Advances
  • Diet and metabolism studies
  • Cancer therapeutics and mechanisms
  • Colorectal Cancer Treatments and Studies
  • Genetic factors in colorectal cancer
  • Anesthesia and Pain Management

Johannes Gutenberg University Mainz
2016-2025

Federal Union of German Associations of Pharmacists
2025

University Medical Center of the Johannes Gutenberg University Mainz
2015-2024

Leipzig University
2024

Radboud University Nijmegen
2024

Radboud University Medical Center
2024

Maastricht University
2018-2023

Maastricht University Medical Centre
2012-2019

TiFN
2015-2019

University Medical Centre Mannheim
2017-2018

Purpose.: To investigate, with the use of spectral-domain optical coherence tomography (SD-OCT), microstructural alterations over time in eyes progressive geographic atrophy (GA) due to age-related macular degeneration. Methods.: Forty-six 26 patients (median age, 77.9 years [interquartile range (IQR), 71.8–81.0]) GA without evidence active or previous neovascular disease at baseline were examined by simultaneous confocal scanning laser ophthalmoscopy (cSLO) and SD-OCT. Serial examinations...

10.1167/iovs.09-4533 article EN Investigative Ophthalmology & Visual Science 2010-04-01

Age-related decline in skeletal muscle mass is at least partly attributed to anabolic resistance food intake. Resistance exercise sensitizes tissue the properties of amino acids.The present study assessed protein digestion and acid absorption kinetics, whole-body balance, myofibrillar synthetic response ingestion different amounts during recovery from older men.Forty-eight healthy men [mean ± SEM age: 66 1 y; body index (kg/m2): 25.4 0.3] were randomly assigned ingest 0, 15, 30, or 45 g milk...

10.1093/jn/nxy263 article EN cc-by Journal of Nutrition 2019-01-30

Introduction. Compliance with immunosuppressive therapy plays a major role in the long-term success of organ transplantation. Thus, strategies to promote compliance posttransplant care are particular interest. At pharmacy department University Hospital Mainz, program for pharmaceutical transplant patients has been developed first time ever. The main objective presented study was examine influence this on liver patients' therapy. Methods. To measure compliance, medication event monitoring...

10.1097/tp.0b013e318199d122 article EN Transplantation 2009-03-27

Sarcopenia, or the loss of muscle mass and strength, is known to increase risk for falls (hip) fractures in older people. The objective this study was assess skeletal fiber characteristics elderly female hip fracture patients.Percutaneous needle biopsies were collected from vastus lateralis 15 healthy young women (20 ± 0.4 years), (79 1.7 with a fall-related (82 1.5 years). Immunohistochemical analyses performed Type I II size, myonuclear satellite cell content.Type size significantly...

10.1093/gerona/glw253 article EN The Journals of Gerontology Series A 2017-01-20

An impaired muscle protein synthetic response to feeding likely contributes loss with aging. There are few data available on the effect of macronutrient composition clinical supplements postprandial in older subjects. The objective study was determine impact a nutritional supplement men. A total 45 nonsarcopenic men (aged 69 ± 1 y; body mass index 25.7 0.3 kg/m2) were randomly assigned ingest 21 g leucine-enriched whey carbohydrate (9 g) and fat (3 (Pro-En), an isonitrogenous amount without...

10.1210/jc.2015-2352 article EN The Journal of Clinical Endocrinology & Metabolism 2015-08-26

Pharmaceutical scientists in the biotechnology industry have traditionally focused on achieving acceptable shelf lives of drug products their original, unopened product unit configuration (e.g., two years stored at 2–8 °C). However, it is now clear that stability considerations extend beyond

10.2146/ajhp140098 article EN American Journal of Health-System Pharmacy 2015-02-26

In this work, 13 jet nebulizers, some of which in different configurations, were investigated order to identify the biopharmaceutical constraints related quality attributes medicinal products, affect their safety, efficiency, compliance, and effectiveness. The aerosolization parameters, including aerosol output, output rate, mass median aerodynamic diameter, fine particle fraction, determined according European Standard EN 13544-1, using sodium fluoride as a reference formulation. A...

10.3390/pharmaceutics11080406 article EN cc-by Pharmaceutics 2019-08-11

The development of recommendations for advancing automated i.v. medication compounding is described.Managing the shift from manual to robotic therapies requires an awareness how automation affects practice and best implement robotics into current practice. An international panel pharmacy professionals, researchers, technology leaders with experience in collaborated during a two-day meeting August 2014 define general set principles broaden understanding fundamental elements worldwide....

10.2146/ajhp151027 article EN American Journal of Health-System Pharmacy 2016-12-22
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