A5100379574- Neuroscience and Neuropharmacology Research
- Stress Responses and Cortisol
- Memory and Neural Mechanisms
- Neuroendocrine regulation and behavior
- Tryptophan and brain disorders
- Anesthesia and Neurotoxicity Research
- Ion channel regulation and function
- EEG and Brain-Computer Interfaces
- Asymmetric Hydrogenation and Catalysis
- Treatment of Major Depression
- Electrocatalysts for Energy Conversion
- COVID-19 and Mental Health
- Posttraumatic Stress Disorder Research
- Receptor Mechanisms and Signaling
- MicroRNA in disease regulation
- Innovative Microfluidic and Catalytic Techniques Innovation
- Cardiac electrophysiology and arrhythmias
- Regulation of Appetite and Obesity
- Gaze Tracking and Assistive Technology
- Genomics and Rare Diseases
- Pancreatic and Hepatic Oncology Research
- Phagocytosis and Immune Regulation
- Evolutionary Psychology and Human Behavior
- Cerebrospinal fluid and hydrocephalus
- Pharmacological Effects of Natural Compounds
Sun Yat-sen University
2015-2025
Jiaxing University
2020-2025
Key Laboratory of Guangdong Province
2025
Tianjin Medical University Cancer Institute and Hospital
2024
Chinese PLA General Hospital
2023
Shanghai Jiao Tong University
2021-2022
Beijing Institute of Technology
2019-2020
Suihua University
2016
Tianjin University of Traditional Chinese Medicine
2014
Daqing City People's Hospital
2012
// Fang Liu 1, 2, 3, * , Qing-Hua Cao 4, De-Jian Lu Bin Luo 2 Xiao-Fang 4 Rong-Cheng 3 Xiao-Guang Wang 1 Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China Faculty Forensic Medicine, ZhongShan School Sun Yat-sen 510080, Cancer Center and Traditional Chinese Medicine-Integrated 510315, Pathology, The First Affiliated Hospital These authors have contributed equally to this work Correspondence to: Wang, e-mail: wxguang@mail.sysu.edu.cn Luo,...
Traumatic brain injury (TBI) is one of the leading causes death and disability. Animal clinical studies TBI have greatly changed practice with development application new technologies. However, forensic science, legal issues related to continue emerge, it still far from satisfactory that practical relevant research findings as evidence in court practice. This review discusses an overview latest progress through neuropathological changes, secondary mechanisms, postmortem neuroimaging,...
Statins have pleiotropic actions against the development of vascular remodeling and incidence ischemic stroke. Although previous studies suggested that posttranslational modification several proteins, such as Rho by mevalonate-derived isoprene groups, geranylgeranyl pyrophosphate or farnesyl pyrophosphate, underlie effects statins, detailed mechanisms remain elusive. Recent growing evidence demonstrated ClC-3 volume-regulated chloride channel plays an important role in cell proliferation,...
Abstract Stress‐induced neuroepigenetic programming gains growing more and interest in the studies of etiology posttraumatic stress disorder (PTSD). However, seldom attention is focused on DNA demethylation fear memory generalization, which core characteristic PTSD. Here, we show that ten‐eleven translocation protein 3 (TET3), most abundant enzyme TET family neurons, senses environmental bridges neuroplasticity with behavioral adaptation during generalization. Foot shock strength dependently...
This study investigated the role of leptin receptor (Lepr) signaling in determining bone mechanosensitivity and also evaluated whether differences Lepr may contribute to differential osteogenic response C57BL/6J (B6) C3H/HeJ (C3H) pair mouse strains mechanical stimuli. shows that a loading strain ∼2,500 με, which was insufficient produce formation B6 mice, significantly increased parameters leptin-deficient ob(-)/ob(-) mice ∼3,000 με yielded greater responses Lepr-deficient db(-)/db(-) than...
In December 2019, coronavirus disease 2019 (COVID-19) appeared in Wuhan (Hubei, China) and subsequently swept the globe. addition to risk of infection, there is a strong possibility that post-traumatic stress disorder (PTSD) may be secondary effect pandemic. Health care workers (HCWs) participating pandemic are highly exposed bear brunt out stressful or traumatic events. this cross-sectional study, we assessed morbidity factors PTSD symptoms among Chinese HCWs. A total 457 HCWs were...
170 SD rats were randomly divided to five groups. Rats in model group, no-acupuncture and acupuncture group subjected MCAO surgery. Acupuncture received 3 consecutive treatments at a parameter that deep 2 mm towards apex nasi thrust/lifted times per second for 1 minute, while no-intervention control Serious neural functional damage sharp decrease of cerebral blood flow, obvious infarction volume, increased nestin mRNA expression, immunopositive cells population (nestin(+), BrdU(+)...
The aim of the present study was to explore mechanism by which microRNA (miR)‑642a‑5p regulates migration and invasion colon cancer cells via collagen type I α1 (COL1A1). characteristics miR‑642a‑5p COL1A1 were analysed through bioinformatics. Cancer normal tissues collected from patients with cancer. miR‑642a‑5p‑ COL1A1‑overexpressing cell lines constructed transfection. A dual‑luciferase reporter assay used verify targeting miR‑642a‑5p. Cell Counting Kit‑8, wound healing Transwell assays...
This study examined the prevalence of posttraumatic stress disorder (PTSD) symptoms in college students 1 month after lockdown Wuhan to identify possible risk factors for PTSD a cross-sectional study.Out 10,502 who responded, 9,274 impacted by COVID-19 pandemic were included our study. was evaluated Impact Event Scale-revised (IES-R). Anxiety/depression Kessler Psychological Distress Scale (K10). Personality traits, coping style, and social support assessed Eysenck Questionnaire-Revised...
Abstract Introduction One hallmark symptom of post‐traumatic stress disorder ( PTSD ) is an inability to restrict fear responses the appropriate predictor. An infusion glucocorticoids GC s) after a high‐intensity shock has been shown induce ‐like memory impairments. In addition s, noradrenergic signalling also recognized as key biomarker underlying symptomatology. Methods To explore role system in impairments, this study, various doses β‐adrenoceptor antagonist propranolol were systemically...
AimsThe ClC-3 chloride channel (and current, ICl,ClC-3) plays an important role in cell volume regulation, proliferation, and apoptosis vascular smooth muscle cells, is a potential target for prevention of remodelling stroke. However, modulation ICl,ClC-3 by intercellular signalling not fully understood. Although it has been suggested that tyrosine phosphorylation required activation, the residues protein are clear. In present study, critical were investigated.
Cerebrovascular remodelling is one of the important risk factors stroke. The underlying mechanisms are unclear. Integrin β3 and volume-regulated ClC-3 Cl(-) channels have recently been implicated as contributors to vascular cell proliferation. Therefore, we investigated role integrin in cerebrovascular related signalling pathway.Cl(-) currents were recorded using a patch clamp technique. expression hypertensive animals was examined by Western blot immunohistochemisty. Immunoprecipitation,...
Facial anthropometric measurements play an important part not only in forensic cases but also clinical treatments. The utilization of 2D photograph methods facial studies to found database with age, gender, ethnicity, and region was expanded by other races little for Han nationality. This study undertaken describe reference ranges proportions nationality compare the characteristics ethnicities. Our subjects focused on full-face photos South China which consisted 1176 healthy person (425...