A5102745538- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Reproductive System and Pregnancy
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Peroxisome Proliferator-Activated Receptors
- Neurological Disease Mechanisms and Treatments
- Mesenchymal stem cell research
- Ophthalmology and Eye Disorders
- Nasolacrimal Duct Obstruction Treatments
- Pregnancy and preeclampsia studies
- Endometriosis Research and Treatment
- Bone Tissue Engineering Materials
- Ectopic Pregnancy Diagnosis and Management
- Facial Rejuvenation and Surgery Techniques
- Traditional Chinese Medicine Analysis
- Ocular and Laser Science Research
- Machine Learning in Healthcare
- Vascular Malformations and Hemangiomas
- Vascular Malformations Diagnosis and Treatment
- Hair Growth and Disorders
- Caveolin-1 and cellular processes
- Preterm Birth and Chorioamnionitis
YangPu Geriatric Hospital
2025
Changchun University of Chinese Medicine
2024
Xuzhou Medical College
2024
Linyi People's Hospital
2024
Shanghai Jiao Tong University
2008-2023
Shanghai Ninth People's Hospital
2007-2023
Shanghai Institute of Hematology
2018-2023
Shandong University of Traditional Chinese Medicine
2021
Soochow University
2018
Foshan Maternity and Child Health Care Hospital
2017-2018
Bone graft substitutes with osteogenic factors alone often exhibit poor bone regeneration due to inadequate vascularization. Combined delivery of and angiogenic from biodegradable scaffolds may enhance regeneration. We evaluated the effects morphogenetic protein 2 (BMP2) vascular endothelial growth factor (VEGF), combined natural coral scaffolds, on repair critical-sized defects in rabbit orbits. In vitro expanded marrow stromal cells (BMSCs) were transfected human BMP2 VEGF165 genes. Target...
The percentages of low birth weight (LBW) increased from 7.7% in 2005 to 11.3% 2011 and declined 8.1% 2017. For very (VLBW) individuals, the proportion -1.0% annually, 2.5% 1.4% Among moderately (MLBW) first 12.8% 5.0% 9.3% 2011, then -3.8% 9.4% 7.0% macrosomia monotone decreased 4.0% 2017, an annual decline -4.0%. Multiple regression analyses showed that boys, maternal age, hypertensive disorders complicating pregnancy (HDCP), diabetes were significant risk factors for LBW. Boys,...
Background: Cornea transplant technology has progressed markedly in recent decades, allowing surgeons to replace diseased corneal endothelium by a thin lamellar structure. A thin, transparent, biocompatible, tissue-engineered substratum with endothelial cells for keratoplasty is currently of interest. Electrospinning nanofibrous structure can simulate the extracellular matrix and have beneficial effects cell culture. Silk fibroin (SF) good biocompatibility but poor mechanical properties,...
Purpose: The aim of this study was to compare the ocular microbial communities in humans with and without demodex blepharitis order elucidate relationship between microorganisms infestation. Methods: Bacterial 16S rRNA genes conjunctival sac samples from 30 patients 14 healthy controls were sequenced using a pyrosequencing method, their bacterial community structures compared by bioinformatics. Results: clustering group significantly distinct control group, higher relative abundances...
The determination of potential transplantable substrates and substitution cells for corneal endothelium transplantation may compensate the shortage cornea donors. Appropriate biodegradable biocompatible tissue-engineered substratum with seed endothelial keratoplasty has been increasingly studied. In present study, electrospun gelatin/polycaprolactone (PCL) collagen/PCL scaffolds were successfully established. Bone marrow progenitor (BEPCs) cultured on these to determine whether promote...
Electrospun hybrid nanofibers prepared using combinations of natural and synthetic polymers have been widely investigated in tissue engineering. In this study, silk fibroin (SF) poly(l-lactic acid-co-ε-caprolactone) (PLCL) scaffolds were successfully by electrospinning. Scanning electron micrographs (SEM) showed that SF/PLCL composed defect-free with a smooth homogeneous fiber morphology. Water contact angle measurements demonstrated the hydrophilic. To assess cell affinity scaffolds, rabbit...
Purpose . To investigate the impact of disease duration on ocular surface during course type 2 diabetes mellitus compared with nondiabetic controls. Methods One hundred twenty diabetic patients were divided into three groups according to duration: less than 5 years, 5–10 and over 10 years. All eyes imaged using a corneal topographer (Oculus Keratograph 5M). Tear film measurements meibography also recorded. Meibomian gland changes scored from 0 6 (meiboscore). Results The noninvasive breakup...
Journal Article Immunohistochemical localization of progesterone receptor in human decidua early pregnancy Get access Jie-Dong Wang, Wang 1 Department Cell Biology, National Research Institute for Family Planning12 Da Hui Si. Beijing 100081, People's Republic China 1To whom correspondence should be addressed Search other works by this author on: Oxford Academic PubMed Google Scholar Yao Fu, Fu Wen-Liang Shi, Shi Peng-Di Zhu, Zhu Jie Cheng, Cheng 3Department Biology Female Clinic Department,...
Background Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a rare autosomal dominant condition characterized by typical eyelid malformations that include blepharophimosis, ptosis, epicanthus inversus, and telecanthus. Methods We retrospectively reviewed 125 consecutive BPES patients who underwent staged surgical intervention from July 2003 to December 2011. All initial medial lateral canthoplasties, followed blephroptosis correction 6 12 months afterward. The parameters were...
Purpose . To evaluate changes in corneal sensitivity and subbasal nerve density after pterygium excision. Methods This prospective trial included 22 eyes with nasal primary 18 controls. Corneal was evaluated using a Cochet–Bonnet esthesiometer the nasal, superior, temporal, inferior, center quadrants of cornea before surgery 10 days, 1 month, 3months surgery. The central analyzed vivo confocal microscopy (IVCM) 3 months Subbasal other parameters were NeuronJ. Nerve tortuosity graded...
To evaluate episcleral vasculature in corneal limbus with optical coherence tomography angiography (OCTA) normal controls, port-wine stain (PWS) patients, and Sturge-Weber syndrome (SWS) patients.Unilateral eyes from 18 controls (25.41 ± 4.00 years), 16 PWS patients (21.35 11.05 8 SWS ipsilateral late-onset glaucoma (22.13 7.82 years). Each subject underwent slit-lamp examination, applanation tonometry, OCTA. All OCTA scans were performed using an system operating at a wavelength of 1050-nm...
The recurrence rates after varicocelectomy vary from 0.9% to 32.2%, especially for patients with the left renal vein entrapment (LRVE). This study aims association between LRVE and varicocele recurrence, find risk factors of LRVE. With design a cohort study, we included 3042 who would undergo modified inguinal microscope-assisted (MHMV). 858 (28.21%) were as group, 2184 (71.79%) without control group. Compared BMI was lower (p < 0.001) in Totally, 18 had surgery, so rate 0.59%. Seventeen...
Apolipoprotein CIII (ApoCIII) has been shown to be associated with the inflammatory response, but mechanism of its effects remains unclear. Because vascular endothelial cells (VECs) play a key role in development inflammation, present study was performed investigate mechanisms induced by ApoCIII VECs. In this study, we screened differentially expressed genes (DEGs) using RNA-sequencing. The results identified 390 up-regulated and 257 down-regulated genes. We GO functional classification KEGG...
A total of 60 women with 6–7 weeks' amenorrhoea were randomly allocated to three groups. The in the first group (control) took a placebo 24 h before undergoing vacuum aspiration. subjects second and third groups given orally 200 mg RU 486, 12 or surgical interruption their pregnancy. Villi decidua collected frozen liquid nitrogen. There no significant differences villous cytosolic steroid concentrations between control 486-treated 486 concentration was lower cytosol than serum....
To investigate the effect and its mechanism of oleuropein on oxidative damage apoptosis astrocytes induced by oxygen-glucose deprivation, circ_TTC3 microRNA-138-5p. Astrocytes were divided into control group, deprivation deprivation+oleuropein 25 μmol/l, 50 100 μmol/l groups, deprivation+si-negative control, si-circ_TTC3 deprivation+oleuropein+plasmid cloning deoxyribonucleic acid plasmid acid-circ_TTC3 group. In comparison with inhibiting rate cell growth, rate, malondialdehyde, lactate...
Purpose: Facial paralysis (FP) leads to diverse periocular complications which threats visual acuity and affects corneal nerve functionally morphologically. This study aims summarize the clinical ophthalmic outcomes, sensation, morphological alterations of subbasal dendritic cells (DCs) in patients with facial paralysis.Methods: We performed a cross-sectional 48 consecutive at one tertiary hospital. Forty-eight healthy participants were enrolled as controls. The images nerves epithelial DCs...