A5033505377- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Plant-Microbe Interactions and Immunity
- Advanced Cellulose Research Studies
- Plant Virus Research Studies
- Nanocomposite Films for Food Packaging
- Plant Pathogenic Bacteria Studies
- RNA modifications and cancer
- Polymer-Based Agricultural Enhancements
- Cancer-related molecular mechanisms research
- Crystallography and molecular interactions
- Electrospun Nanofibers in Biomedical Applications
- Legume Nitrogen Fixing Symbiosis
- Reproductive Biology and Fertility
- Circular RNAs in diseases
- Biopolymer Synthesis and Applications
- Plant tissue culture and regeneration
- Plant Disease Resistance and Genetics
- Asymmetric Synthesis and Catalysis
- Advanced MRI Techniques and Applications
- Nanoparticles: synthesis and applications
- Liver Disease Diagnosis and Treatment
- Polysaccharides and Plant Cell Walls
- Antimicrobial agents and applications
- biodegradable polymer synthesis and properties
Southwest University
2017-2025
Ministry of Education of the People's Republic of China
2023-2024
Ningxia Medical University
2024
Tianjin Medical University
2019-2022
Nanjing Agricultural University
2022
Jilin University
2010-2020
Chongqing Institute of Green and Intelligent Technology
2019
Lanzhou University
2011-2017
Tsinghua University
2016-2017
State Key Laboratory of Applied Organic Chemistry
2011-2012
N6-Methyladenosine (m6A) is the most common internal modification of eukaryotic messenger RNA (mRNA) that occurred on N6 nitrogen adenosine. However, roles m6A in oral squamous cell carcinoma (OSCC) are still elusive. Here, we investigate function and mechanism methyltransferase-like 3 (METTL3) OSCC tumorigenesis. Clinically, METTL3 was significantly upregulated tissue samples correlated with poor prognosis patients. Functionally, loss gain studies illustrated promoted proliferation,...
DNA hydrogel has aroused widespread attention because of its unique properties. In this work, the DNA-modified magnetic nanoparticles were integrated into mainframe hydrogel, resulting in DNA-MNP hydrogel. Under field, can be remotely deformed various shapes, driven to jump between two planes and even climb hill. By applying triggers, such as temperature, enzyme, specifically undergo sol-gel transition. This work not only imparts with a new fold property but also opens platform smart...
Tissue engineering has long been a challenge because of the difficulty addressing requirements that such an engineered tissue must meet. In this paper, we developed new "brick-to-wall" based on unique properties DNA supramolecular hydrogels to fabricate three-dimensional (3D) tissuelike structures: different cell types are encapsulated in hydrogel bricks which then combined build 3D structures. Signal responsiveness cells through gels was evaluated and it discovered gel permits migration 3D....
As a kind of promising nanopesticide, in contrast to traditional synthesis strategies, the application polysaccharide silver nanoparticle preparation can improve its stability and avoid usage harmful substances. In this work, two-step strategy for synthesizing nanoparticles (A-AgNPs) from aldehyde-modified sodium alginate (ASA) was introduced. The size A-AgNPs synthesized be controlled 6 40 nm with high dispersibility water. Furthermore, compared naked AgNPs (n-AgNPs), showed improved...
Improving the efficiency and prolonging duration of pesticides are great significance in agricultural production. In this work, based on antiviral compound chloroinconazide (CHI) synthesized previously, improvement fabricated CHI-loaded alginate-based nanogel (CHI@ALGNP) was studied. It found that CHI@ALGNP showed higher foliar adhesion than CHI exhibited a sustained release for up to 7 days. could also continuously activate reactive oxygen species antioxidant levels induce increase...
<title>Abstract</title> Zinc (Zn<sup>2+</sup>) is an essential micronutrient that regulates plant growth, immunity, and antiviral defense mechanisms. However, its limited bioavailability often necessitates excessive application, resulting in inefficiencies production environmental stress. In response, we propose environmentally friendly sustainable approach to enhance the utilization of Zn<sup>2+</sup>. We developed CNC@PDA@Zn<sup>2+</sup> by embedding Zn<sup>2+</sup> into polydopamine (PDA)...
The asymmetric allylic substitution reaction of MBH carbonates with allylamines has been developed, which affords N-allyl-β-amino-α-methylene esters in high yields and enantioselectivities. After a subsequent ring-closure metathesis the products, series optically active 2,5-dihydropyrroles could be obtained smoothly without any loss enantioselectivity. Finally, tentative mechanism for rationalization proposed.
At present, the management of Phytophthora capsici (P. capsici) mainly relies on chemical pesticides. However, along with resistance generated by P. to these pesticides, toxicity and non-degradability this molecule may also cause serious environmental problems. Herein, a new bio-based nano-antifungal material (CNC@CTAB) was made coating hexadecyl trimethyl ammonium bromide (CTAB) surface cellulose nanocrystal (CNC). This then applied prevention capcisi. particle facilely fabricated mixing...
Abstract Silver (Ag)-containing agents or materials are widely used today in plant protection for their antimicrobial activity. In view of the superior inhibitory ability biosynthesized (aldehyde-modified sodium alginate based) silver nanoparticles (AgNPs) against pathogenic fungi our previous research, here we explored antagonistic effect AgNPs on bacteria and underlying mechanism. We selected Pseudomonas syringae pv. tabaci , causal agent tobacco wildfire disease, as target found that 1.2...
Abstract BACKGROUND Copper nanoparticles (CuNPs) can release copper ions (Cu 2+ ) to control bacterial diseases on crops. However, the high concentration of CuNPs applied in disease controlling highly limit their application. In this work, by situ reducing alginate nanogels and coated with cetyl trimethyl ammonium chloride (CTAC), a CuNP composite nanogel was fabricated as new nanopesticide low content. RESULTS Data showed that CTAC coating would affect antibacterial activity leaf surface...
Abstract Background Emerging transcriptome-wide high-throughput screenings reveal the landscape and functions of RNAs, such as circular RNAs (circRNAs), in human cancer. In addition, post-transcriptional RNA internal modifications, especially N 6 -methyladenosine (m A), greatly enrich variety metabolism. However, m A modification on circRNAs has yet to be addressed. Results Here, we report an epitranscriptome-wide mapping A-modified A-circRNA) oral squamous cell carcinoma (OSCC). Utilizing...
Abstract BACKGROUND The application of chemical pesticides in control plant bacterial disease may cause potential environmental pollution. Herein, based on the resistance‐inducing ability and special rod‐like structure with high aspect ratio bio‐derived chitin nanocrystals (ChNC), a new Cu composite nanoparticle was fabricated (ChNC@Cu). antibacterial activity systematically studied, its safety evaluated. RESULTS TEM, FTIR, ICP other characterization methods proved that ChNC@Cu is nano...