A5002558478- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Reproductive Physiology in Livestock
- Genetics and Plant Breeding
- Effects of Environmental Stressors on Livestock
- Cancer-related molecular mechanisms research
- Lymphoma Diagnosis and Treatment
- Integrated Energy Systems Optimization
- Ruminant Nutrition and Digestive Physiology
- Renewable Energy and Sustainability
- Lung Cancer Treatments and Mutations
- Optimal Power Flow Distribution
- Smart Grid Energy Management
- Electric Power System Optimization
- Advanced Radiotherapy Techniques
- Reproductive Biology and Fertility
- Animal Behavior and Welfare Studies
- Microgrid Control and Optimization
- Esophageal Cancer Research and Treatment
- Hybrid Renewable Energy Systems
- Power System Reliability and Maintenance
Universität Hamburg
2023-2024
Hamburg University of Technology
2023-2024
University of Göttingen
2015-2017
University of Duisburg-Essen
1991
Abstract Background Milk production traits are complex and influenced by many genetic environmental factors. Although extensive research has been performed for these traits, with associations unveiled thus far, due to their crucial economic importance, architecture, the fact that causal variants in cattle still scarce, there is a need better understanding of background. In this study, we aimed identify new candidate loci associated milk German Holstein cattle, most important dairy breed...
Abstract Background Reproduction is vital to welfare, health, and economics in animal husbandry breeding. Health reproduction are increasingly being considered because of the observed genetic correlations between reproduction, conformation, performance traits dairy cattle. Understanding detailed architecture underlying these would represent a major step comprehending their interplay. Identifying known, putative or novel associations genomics could improve while allowing further adjustments...
Abstract Background The use of genome-wide association studies (GWAS) has led to the identification numerous quantitative trait loci and candidate genes in dairy cattle. To obtain sufficient power GWAS identify nucleotides, whole-genome sequence data is required. Sequence facilitates potential causal variants; however, sequencing whole genomes still expensive for a large number animals. Imputation quick efficient way obtaining from datasets. Milk production traits are complex influenced by...
Genomic analyses commonly explore the additive genetic variance of traits. The non-additive variance, however, is usually small but often significant in dairy cattle. This study aimed at dissecting eight health traits that recently entered total merit index Germany and somatic cell score (SCS), as well four milk production by analysing dominance components. heritabilities were low for all (between 0.033 mastitis 0.099 SCS), moderate 0.261 energy yield 0.351 yield). For traits, contribution...
Abstract Background Claw diseases and mastitis represent the most important health issues in dairy cattle with a frequently mentioned connection to milk production. Although many studies have aimed at investigating this more detail by estimating genetic correlations, they do not provide information about causality. An alternative is carry out Mendelian randomization (MR) using variants investigate effect of an exposure on outcome trait mediated variants. No study has yet investigated causal...
Abstract Mixed models can be considered as a type of penalized regression and are everyday tools in statistical genetics. The standard mixed model for whole genome (WGR) is ridge best linear unbiased prediction (RRBLUP) which based on an additive marker effect model. Many publications have extended the WGR approach by incorporating interactions between loci or genes environment. In this context regressions with interactions, it has been reported that translating coding single nucleotide...
The aim of this study was to analyze possible effects semen type (conventional vs. female sexed) and calf sex on fertility production traits. For purpose, field data German Holstein heifers in Lower Saxony were evaluated. Sexed mainly used for first insemination. 87.0% calves born from sexed semen, while 52.7% conventional semen. Heifers inseminated with average 43 48 days younger at their calving than Calf had an influence the ease dystocia rates. Male showed higher scores caused a risk...
Abstract Background This paper highlights the relationships between economic weights, genetic progress, and phenotypic progress in genomic breeding programs that aim at generating complex, i.e., multi-trait, objectives via a combination of estimated values for different trait complexes. Results Based on classical selection index theory with quantitative models, we provide methodological framework calculating expected all components complex objective. We further an approach to study...
OPINION article Front. Plant Sci., 19 November 2021Sec.Plant Breeding https://doi.org/10.3389/fpls.2021.728567
In order to meet ever-stricter climate targets and achieve the eventual decarbonization of energy supply German industrial metropolises, focus is on gradually phasing out nuclear power, then coal gas combined with increased use renewable sources employing hydrogen as a clean carrier. While complete electrification households transportation sector may be ultimate goal, transitional phase necessary such massive well rapid expansion electrical distribution grid infeasible. Additionally,...
In the course of energy transition, distribution grid operators heat, gas and power must adapt their expansion planning to new challenges. Up now, grids have mainly been adapted unidirectionally based on peak loads consumers. future grids, flexible consumers, distributed generation as well sector coupling will determine requirements constraints for planning. order integrate individual operators, this paper proposes an approach in which additional downstream process step extends established...
Over the last decades, it was subject of many studies to investigate genomic connection milk production and health traits in dairy cattle. Thereby, incorporating functional information analyses has been shown improve understanding biological molecular mechanisms shaping complex accuracies prediction, especially small populations across-breed settings. Still, little is known about contribution different evolutionary genome partitioning subsets health. Thus, we performed a uni- bivariate...