- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Biofuel production and bioconversion
- Monoclonal and Polyclonal Antibodies Research
- Blood groups and transfusion
- Respiratory viral infections research
- Antibiotic Resistance in Bacteria
- Studies on Chitinases and Chitosanases
- Electrochemical Analysis and Applications
- Catalysis for Biomass Conversion
- Viral gastroenteritis research and epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- HIV Research and Treatment
- Herpesvirus Infections and Treatments
- Immune Cell Function and Interaction
- Virus-based gene therapy research
- Supercapacitor Materials and Fabrication
- Conducting polymers and applications
- Enzyme Production and Characterization
- Enterobacteriaceae and Cronobacter Research
- Advanced Sensor and Energy Harvesting Materials
East China University of Science and Technology
2024
State Key Laboratory of Chemical Engineering
2024
The University of Tokyo
2016-2022
Jiangsu University
2018
South China Agricultural University
2018
Guangzhou University
2018
Jiangsu Academy of Agricultural Sciences
2018
117th Hospital of People's Liberation Army
2017
In a hepatitis B virus (HBV)‑infected population, persistently low expression levels of serum HBV antigen (HBsAg) are present, particularly in chronic asymptomatic carriers (ASCs). The present study sequenced the Pre‑S gene, and aimed to elucidate its features ASCs with HBsAg compared established reference gene sequences from high expression. A total 1,308 were grouped according (cut‑off value, 10 IU/ml), clinical characteristics analyzed detail. was 276 low‑level HBsAg; addition, 100...
BACKGROUND The aim of this study was to investigate the clinical characteristics individuals with chronic hepatitis B virus (HBV) infection persistent low levels surface antigen (HBsAg) and undertake a correlation analysis characteristics. MATERIAL AND METHODS included 1,204 subjects HBV infection. Serum HBsAg, envelope (HBeAg), core (HBcAg) were measured using chemiluminescent microparticle immunoassay (CMIA) neutralization test. DNA real-time fluorescence quantitative polymerase chain...
This study aimed to investigate hepatitis B virus (HBV) infection in military personnel eastern China, which will provide a basis for the prevention of HBV infection. A total 15,508 soldiers and 2386 officers were recruited from camps China. The markers, deoxyribonucleic acid, serotypes, genotypes serum detected analyzed. Hepatitis surface antigen (HBsAg) positive rate was 0.44% soldiers, whom low-level HBsAg accounted 88.24%. 1.72% 12.20%. There significant differences prevalence high-level...
In this study, a bamboo-derived magnetic carbonaceous solid acid catalyst (BC@Fe3O4@SO3H) was synthesized by FeCl3 impregnation, which followed incomplete carbonization and -SO3H group functionalization. FT-IR, XRD, TGA results showed that the prepared contained -SO3H, -COOH, phenolic -OH groups. It exhibited poor adsorption ability for dominating sugars released during catalytic conversion process. The presented high activity depolymerization of corncob hemicellulose. Warm water immersion...
This study aimed to establish a general and efficient dissociation technique for detecting antibodies in circulating immune complexes (CICs) serum evaluate its clinical application. CICs were efficiently separated from specimens using polyethylene glycol double-precipitation. The best conditions anti-HBs HBsAg-ICs pH of 1.80, incubation at 15 °C 5-10 min, detection within 10 min after neutralization. mean rate, reproducibility, recovery rate specificity the new 64.3%, < 5.97, 95.4 100%,...
Certain patients with hepatitis B virus (HBV) infection present persistently low levels of serum surface antigen (HBsAg) and have been indicated to rates HBV nucleic acid replication. To explore the serological molecular epidemiological characteristics population low‑level HBsAg in study, associated markers virologic genotype detection were performed accordingly. Determination was using a chemiluminescence immunoassay from which 2,544 out 45,256 adults who underwent routine health...
Abstract Circulating immune complexes (CICs) are produced during the response. It is more clinically important to establish a general and efficient CICs dissociation technique for detection of antigens other than free in serum. Polyethylene glycol (PEG) two‐precipitation separation glycine‐HCl as buffer system were employed develop separate from serum dissociate CICs. The measurement value new PEG was higher traditional precipitation technique. There slight differences conditions HCV...
We detected the serum HBsAg immune complex (HBsAg-CIC) and sequenced HBV S gene in these patients to reveal association between sustained low-level expression of mutated sequence characteristics, protein function changes, formation.A total 204 samples were collected divided into high-level (n = 60, level >10 IU/ml) 144, ≤ 10 groups. The clinical epidemiological data two groups statistically compared. According different serological patterns genotypes, HBsAg-CIC results subgroups, then...