A5101909729- Plant tissue culture and regeneration
- Antibiotic Resistance in Bacteria
- Gut microbiota and health
- Cancer, Hypoxia, and Metabolism
- Probiotics and Fermented Foods
- Glycosylation and Glycoproteins Research
- Transgenic Plants and Applications
- Advances in Cucurbitaceae Research
- RNA modifications and cancer
- Mitochondrial Function and Pathology
- Animal Virus Infections Studies
- Ferroptosis and cancer prognosis
- Forest, Soil, and Plant Ecology in China
- Virus-based gene therapy research
- Mycobacterium research and diagnosis
- Epigenetics and DNA Methylation
- Enterobacteriaceae and Cronobacter Research
- Flowering Plant Growth and Cultivation
- Clostridium difficile and Clostridium perfringens research
- Cancer, Lipids, and Metabolism
- Bacterial biofilms and quorum sensing
- Evolutionary Game Theory and Cooperation
- Plant Pathogens and Fungal Diseases
- Polymer-Based Agricultural Enhancements
- Bacterial Identification and Susceptibility Testing
Zunyi Medical University
2023-2024
Northeast Agricultural University
2018-2023
Linyi University
2021
Shandong Academy of Agricultural Sciences
2021
117th Hospital of People's Liberation Army
2016-2018
Tropical Crops Genetic Resources Institute
2017
Chinese Academy of Tropical Agricultural Sciences
2017
Huaibei Mining (China)
2016
China Resources (China)
2016
Kunming Institute of Botany
2014
Genomic resources have significantly impacted plant biology research in recent years.Cell has been further enabled by an ongoing revolution visualization technologies.Using fluorescent proteins (FPs), we now unprecedented views of cellular architecture, and can study real-time dynamics cell structure, function, protein localization.To date, these technologies most widely used Arabidopsis (Arabidopsis thaliana); however, the grasses provide a unique opportunity to underlying mechanisms...
Abstract Background Colonization of intestinal microbiota in ruminant during the early life is important to host health, metabolism and immunity. Accumulating evidence revealed ameliorative effect milk replacer administration gut microbial development early-weaned ruminants. Yimeng black goats (YBGs) inhabiting Shandong, China show a complex ecosystem, but studies their are still insufficient report. Here, this study was performed investigate how develops weaned YBGs with age replacer....
Abstract Background As a key enzyme in ceramide synthesis, longevity assurance homologue 2 (LASS2) has been indicated to act as tumour suppressor variety of cancers. Ferroptosis is involved processes; however, the role LASS2 regulating ferroptosis yet be explored. This article explores potential underlying mechanisms involved. Methods Bioinformatics tools and immunohistochemical staining were used evaluate expression, results analysed relation overall survival clinical association multiple...
Abstract Metabolic reprogramming is widely recognized as a hallmark of malignant tumors, and the targeting metabolism has emerged an appealing approach for cancer treatment. Mitochondria, pivotal organelles, play crucial role in metabolic regulation tumor cells, their morphological functional alterations are intricately linked to biological characteristics tumors. As key regulatory subunit mitochondria, mitochondrial inner membrane protein (IMMT), plays vital degenerative diseases, but its...
Aim: This study aimed to evaluate the differences of biosurfactants produced by two Lactobacillus helveticus strains against biofilm formation Staphylococcus aureus in vitro and vivo. Materials & methods: Scanning electron microscopy, Real time-quantitative PCR (RT-qPCR) cell assay were used analyze inhibiting effect formation. Results conclusion: showed that have anti-adhesive effects on vivo vitro. The biofilm-formative genes autoinducer-2 signaling regulated these characteristics,...
The mink circovirus (MiCV), a newly discovered pathogen, is associated with diarrhea in farmed minks. prevalence and economic importance of this virus remain poorly understood, quantitative method for diagnosis MiCV infection has not been established. This research aims to develop highly specific, sensitive, assay MiCV. A Real-Time polymerase chain reaction (qPCR) was developed detect different isolates the samples. qPCR system sensitive detection limit as low 10 viral DNA copies....
Abstract Background This research is aimed to study the resistance and molecular epidemiological characteristics of carbapenem-resistant Klebsiella pneumoniae (CRKP). Methodology 38 isolated CRKP strains were collected from clinical specimens. Results The rates more than 70.0%. Ampicillin had highest among them (100.0%). 34 (89.5%) carried bla KPC-2 gene, 3 (7.9%) IMP-4 gene. 36 (94.7%) SHV 29 (76.3%) TEM 26 (68.4%) CT-M 7 (18.4%) DHA-1 15 (39.5%) in lost two fenestra proteins, ompK35...
In order to provide a scientific water management for the standardized cultivation, effects of soil content on seedlings growth and active ingredients S. miltiorrhiza were studied.A stress experiment with pot culture was applied study different growth, biomass accumulation tanshinone, salvianolic acid B mineral nutrition miltiorrhiza.Soil had serious influence yield, outer appearance inner quality when under severe drought or too much water. But shoot root increased significantly mild...
Abstract LASS2 functions as a tumor suppressor in hepatocellular carcinoma (HCC), the most common type of primary liver cancer, but underlying mechanism its action remains largely unknown. Moreover, details on role and downstream mechanisms Cholangiocarcinoma (CCA) hepatoblastoma (HB), are rarely reported. Herein, overexpression was found to significantly inhibit proliferation, migration, invasion induce apoptosis hepatoma cells with wild-type (HB cell line HepG2) mutated p53 (HCC HCCLM3 CCA...
Effective targeted therapeutic strategies for triple-negative breast cancer (TNBC), the most malignant subtype of cancer, are currently lacking. Ferroptosis has been reported to be associated with onset and advancement various types, including TNBC. However, there limited studies on correlation between TNBC ferroptosis-related genes. In addition, potential biomarkers ferroptosis in need further investigation. The present study aimed assess prognostic role a novel gene signature context was...
Corymbia ptychocarpa subsp. aptycha, a member of Myrtaceae, is native to north-western Australia. It was introduced China for ornamental landscape applications because its unique leaves and beautiful terminal inflorescences. An efficient micropropagation protocol needed the mass propagation aptycha. Disinfested shoot tips with one axillary bud (1.0–1.5 cm) were cultured on Murashige Skoog (MS) medium containing 6-benzylaminopurine (6-BA) 1-naphthaleneacetic acid (NAA). After culture 30 days,...
Objective To evaluate the performance of Carba NP test (CNP) for detection carbapenemases in carbapenem-non-susceptive Enterobacteriaceae. Methods Carbapenemases Enterobacteriaceae strains isolated from clinical specimens 117th hospital PLA January 2010 to December 2014 were detected by both CNP and modified Hodge (MHT), corresponding results analyzed compared Chi-square using SPSS version 19.0. Data acquired PCR used as standard. Results Of 253 strains, 188 positive 65 negative...
Explaining the evolution of cooperation remains one important problems in both biology and social science. Classical theories mainly based on an assumption that cooperative players are symmetrically interacted. However, almost all well-studied systems showed fact asymmetrically interacted asymmetric interaction might greatly affect behavior involved players. Considering selection pressure resources, we present a model possesses four strategies: strength- (SC), strength-defection (SD),...
Excessive nitrogen (N) fertilization in glasshouse fields greatly increases N loss and fossil-fuel energy consumption resulting serious environmental risks. Microbial inoculants are strongly emerging as potential alternatives to agrochemicals offer an eco-friendly strategy reduce our dependence on synthetic chemical fertilizers. Effects of a N-fixing strain Pseudomonas protegens CHA0-ΔretS-nif ginger plant growth, yield, nutrient uptake, earthworm biomass the microbial community were...
e13135 Background: Response to trastuzumab in metastatic breast cancer correlates with expression of the high affinity allele activating Fcγ receptor IIIA (CD16A). We engineered MGAH22, a HER2 mAb specificity and similar trastuzumab, have an optimized Fc domain that confers increased binding both alleles CD16A decreased CD32B (the inhibitory FcγRIIB). Methods: MGAH22 was compared RES120, identical except for wild type domain. Antibody-dependent cell cytotoxicity (ADCC) assays were performed...