A5101771932- COVID-19 Clinical Research Studies
- Bacteriophages and microbial interactions
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Epigenetics and DNA Methylation
- Cancer, Lipids, and Metabolism
- Virus-based gene therapy research
- Ferroptosis and cancer prognosis
- Antibiotic Resistance in Bacteria
- CRISPR and Genetic Engineering
- Viral gastroenteritis research and epidemiology
- Gastric Cancer Management and Outcomes
- Animal Virus Infections Studies
- Esophageal Cancer Research and Treatment
- Medical Research and Treatments
- Advanced biosensing and bioanalysis techniques
- Esophageal and GI Pathology
- Microbial infections and disease research
- Viral Infectious Diseases and Gene Expression in Insects
- Educational Reforms and Innovations
Foshan University
2024
Beijing University of Chemical Technology
2023-2024
Zunyi Medical University
2023-2024
Xi'an Honghui Hospital
2019
Xi'an Jiaotong University
2019
Abstract Background As a key enzyme in ceramide synthesis, longevity assurance homologue 2 (LASS2) has been indicated to act as tumour suppressor variety of cancers. Ferroptosis is involved processes; however, the role LASS2 regulating ferroptosis yet be explored. This article explores potential underlying mechanisms involved. Methods Bioinformatics tools and immunohistochemical staining were used evaluate expression, results analysed relation overall survival clinical association multiple...
Esophageal adenocarcinoma (EAC) is an aggressive disease with high mortality and overall 5-year survival rate of less than 20%. Barrett's esophagus (BE) the only known precursor EAC, patients BE have a persistent excessive risk EAC over time. Individuals are up to 30-125 times more likely develop general population. Thus, early detection could significantly improve EAC. Due limitations endoscopic surveillance lack clinical stratification strategies, molecular biomarkers should be considered...
The emergence of phage-resistant bacterial strains is one the biggest challenges for phage therapy. However, emerging bacteria are often accompanied by adaptive trade-offs, which supports a therapeutic strategy called "phage steering". key to steering guide population toward an evolutionary direction that favorable treatment. Thus, it important systematically investigate impacts phages targeting different receptors on fitness population. Herein, we employed 20 impose strong pressure host...
Effective targeted therapeutic strategies for triple-negative breast cancer (TNBC), the most malignant subtype of cancer, are currently lacking. Ferroptosis has been reported to be associated with onset and advancement various types, including TNBC. However, there limited studies on correlation between TNBC ferroptosis-related genes. In addition, potential biomarkers ferroptosis in need further investigation. The present study aimed assess prognostic role a novel gene signature context was...
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Background Although many people received the COVID-19 vaccine, shortly after Chinese government announced that three-year restrictions were being eased, first large number of Omicron infections appeared in Beijing. In this study, we describe epidemiological characteristics, clinical severity, and time-to-event distribution patients infected with SARS-CoV-2 Beijing outbreak, comparing those who booster vaccine cases full/partial vaccines. Methods collected epidemiological, clinical,...
<title>Abstract</title> <bold>Background </bold>Although many people received the COVID-19 vaccine, shortly after Chinese government announced that three-year restrictions were being eased, first large number of Omicron infections appeared in Beijing. We describe epidemiological characteristics, clinical severity, and time-to-event distribution patients infected with SARS-CoV-2 Beijing outbreak, comparing those who booster vaccine cases full/partial vaccines. <bold>Methods </bold>We...
Chickens infected with FAdV-4 and FAdV-8b both exhibit hepatic lesions characterized by hemorrhagic necrosis intranuclear inclusion body formation. However, only induces pericardial effusion acute mortality in chickens. To investigate the similarities differences pathogenicity of HPS IBH, this study intends to compare infectivity FAdV-8b, 2 serotypes fowl adenovirus isolated our laboratory. The viruses were respectively inoculated subcutaneously into SPF chicks at neck. clinical...
Although many people received the COVID-19 vaccine, shortly after Chinese government announced that three-year restrictions were being eased, first large number of Omicron infections appeared in Beijing. We describe epidemiological characteristics, clinical severity, and time-to-event distribution patients infected with SARS-CoV-2 Beijing outbreak, comparing those who booster vaccine cases full-course/partial-course vaccines. collected epidemiological, clinical, laboratory, management data...
Local agriculture-related universities must have certain regional advantages, advantages of agricultural characteristics, human resources, and science technology in the process implementing rural revitalization strategy. Using literature research investigation methods, combined with experience colleges universities, veterinary discipline correspondent yard, this study discusses our education teaching practice talent training mode innovation, improving quality on strategic path united front...
Phage contamination has become a major concern for industrial bacteria, such as Escherichia coli BL21(DE3), used in fermentation processes. Herein, we report CRISPR/Cas9 defense system-based strategy to precisely prey and degrade phage DNA decontaminate target phages. First, isolated novel from substrates with BL21(DE3) the host, named TR1. It showed typical podovirus morphology head diameter of 51.46 ± 2.04 nm tail length 9.31 2.77 nm. The burst size TR1 was 151 PFU/cell, suggesting its...