A5013400948- Child and Adolescent Psychosocial and Emotional Development
- Cancer Diagnosis and Treatment
- Mental Health Research Topics
- Head and Neck Cancer Studies
- Tumors and Oncological Cases
- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- COVID-19 and Mental Health
- Advanced Breast Cancer Therapies
- Early Childhood Education and Development
- Digital Mental Health Interventions
- Suicide and Self-Harm Studies
- Psychological and Temporal Perspectives Research
- Identity, Memory, and Therapy
- Youth Substance Use and School Attendance
- Atherosclerosis and Cardiovascular Diseases
- Cancer Risks and Factors
- Peroxisome Proliferator-Activated Receptors
- Global Cancer Incidence and Screening
- Lipoproteins and Cardiovascular Health
- Occupational and environmental lung diseases
- Multiple and Secondary Primary Cancers
- Maternal Mental Health During Pregnancy and Postpartum
- Health and Well-being Studies
KU Leuven
2021-2025
Maastricht University Medical Centre
2025
Maastricht University
2016-2024
Leiden University
2021-2024
Erasmus University Rotterdam
2022
University of Antwerp
2021
COVID-19 lockdown measures have profoundly impacted adolescent' daily life, with research suggesting an increase in irritability, stress, loneliness, and family conflict. A potential protective factor is parent-child relationship quality; however, no studies investigated this. We used data from SIGMA, a longitudinal, experience sampling cohort study, which N = 173 adolescents aged 11 to 20 were tested before during COVID-19. Multilevel analyses showed decreased daily-life irritability...
The aim of this study was to explore the feasibility and effectiveness mindful walking in nature as a possible means maintain mindfulness skills after mindfulness-based cognitive therapy (MBCT) or stress reduction (MBSR) course. Mindful alongside river Rhine took place for 1, 3, 6, 10 days, with control period similar number 1 week before period. In 29 participants, experience sampling method (ESM) performed during Smartphones offered items on positive negative affect state at random times...
This study determines the prognostic value of luminal-like subtype in patients with hormone receptor-positive breast cancer and explores whether efficacy extended anastrozole therapy differs between luminal A-like versus B-like tumours. The phase III DATA (NCT00301457) examined 6 3 years postmenopausal women early-stage who had received 2-3 tamoxifen. Patients available formalin-fixed paraffin-embedded tissue blocks were identified classified by immunohistochemical subtype. Distant...
Childhood adversity is known to predispose a wide array of psychopathology in adolescence and early adulthood. Identity development, being crucial developmental task during adolescence, has been suggested affect this association. Nonetheless, research on the role identity processes scarce. The current study aims investigate how exploration commitment may impact association between childhood psychopathology. We cross-sectionally investigated adversity, (i.e., breadth depth, making,...
Purpose: Self-harm is a leading cause of death and injury worldwide especially common amongst adolescents. Adverse childhood experiences (ACEs) are characterized as risk factor for self-harm within the Integrated-Motivational Volitional (IMV) model. However, it unclear how ACEs relate to unfolds in daily-life, research investigating potential protective factors association between scarce. Here, we investigated whether were associated with lifetime daily-life using Experience Sampling...
Cancer of unknown primary (CUP) is a metastasised malignancy with no identifiable tumour origin. Despite the frequent occurrence and bleak prognosis CUP, research into its aetiology scarce. Our study investigates alcohol consumption, tobacco smoking CUP risk. We used data from Netherlands Cohort Study, cohort that includes 120 852 participants aged 55 to 69 years, who completed self-administered questionnaire on cancer risk factors at baseline. follow-up was established through record...
Adolescence is a vulnerable period for psychopathology development, and certain parenting styles are consistent robust predictors of broad range mental health outcomes. The mechanisms through which maladaptive affect the development assumed to be largely social in nature. Yet, linking unexplored at arguably most important level functioning: daily life. This study aims identify associations between three styles, experience daily-life interactions. Furthermore, we aim explore extent these...
Early findings on the impact of COVID-19 pandemic adolescents, suggest that – despite being at lowest physical health risk both their mental and day-to-day social lives are strongly affected. In this longitudinal study, we assessed changes in adolescent psychopathology symptoms, quality quantity daily-life interactions, relationship between interactions symptoms before during pandemic.A sample n=173 Flemish adolescents (mean age=16.0 latest measurement; 89% girls) from SIGMA cohort was...
Background: Self-harm is a leading cause of death and injury worldwide especially common amongst adolescents. Adverse childhood experiences (ACEs) are characterized as risk factor for self-harm within the Integrated-Motivational Volitional (IMV) model. However, it remains unclear whether ACEs associated with thoughts, behaviours, or both. Moreover, research that investigates potential protective factors in association between scarce. Here, we investigated were lifetime current thoughts...
Childhood adversity is associated with psychopathology. First evidence in adults suggests that threat anticipation, i.e., an enhanced anticipation of unpleasant events creating enduring sense threat, may be a putative mechanism linking childhood to This study aimed test the indirect effect on psychopathology via large community sample adolescents. We measured trauma and bullying victimization (as indicators adversity), general prodromal psychotic symptoms adolescents aged 12-16 years (full...
Background: Previous research suggests attachment is a vulnerability factor for self-harm thoughts and behaviors in adults. Yet, few studies have investigated this relationship during adolescence, although adolescence critical period changes relationships onset. Whether how relates to as measured daily life also unknown. Aims: To investigate whether paternal, maternal, peer are associated with lifetime current adolescent behaviors. Additionally, examine different bonds interact relation...
Cancer of unknown primary (CUP) is a metastatic malignancy with an unidentifiable tumour origin. Previous studies suggest that type 2 diabetes mellitus (T2DM) and CUP risk are associated. This study examines the association in greater depth by investigating T2DM status, duration, age at diagnosis, medication was being used relation to CUP.Data were utilized from Netherlands Cohort Study, prospective cohort includes 120 852 participants aged 55-69 years baseline 1986. All completed...
Background: Research suggests that most mental health conditions have their onset in the critically social period of adolescence. Yet, we lack understanding potential processes underlying early psychopathological development. We propose a conceptual model where daily-life interactions and skills form an intermediate link between known risk protective factors (adverse childhood experiences, bullying, support, maladaptive parenting) psychopathology adolescents – is explored using...
Cancer of Unknown Primary (CUP) is a metastatic disease for which the primary tumour origin could not be identified during life. Few studies have investigated risk factors associated with this disease. This study investigates anthropometry, physical activity and CUP risk.Data used from Netherlands Cohort Study, includes 120,852 participants aged 55-69 years. All cohort members completed self-administered questionnaire on cancer at baseline in 1986. follow-up was established through record...
Cancer of unknown primary (CUP) is a metastasised cancer for which no lesion could be identified during life. Research into CUP aetiology with respect to dietary factors particularly scarce. This study investigates whether meat consumption associated risk.
Objective Cancer of Unknown Primary (CUP) refers to the presence metastatic lesions, with no identifiable primary site during patient's lifetime. Poor survival and lack available treatment highlight need identify potential CUP risk factors. We investigated whether a family history cancer is associated increased risk. Methods performed case cohort analysis using data from Netherlands Cohort Study, which included total 963 cases 4,288 subcohort members. A Cox Proportional Hazards Regression...
Adolescent solitude was drastically impacted by the COVID-19 pandemic. As is crucial for adolescent development through its association with both positive and negative developmental outcomes, it critical to understand how adolescents' daily-life solitary experiences changed as a result of
This study aims to determine whether real-world overall survival (OS) of patients diagnosed with de Novo human epidermal growth factor receptor 2 positive (HER2+) advanced breast cancer (ABC) improved in the Netherlands since introduction pertuzumab 2013. Patients systemically treated for HER2+ ABC 2008-2017 were retrieved from Cancer Registry. Vital status was obtained on January 31, 2023. OS estimated using Kaplan-Meier method and compared between 2013-2017 2008-2012 through multivariable...