A5044140671- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Thyroid and Parathyroid Surgery
- Pancreatic and Hepatic Oncology Research
- Celiac Disease Research and Management
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Microscopic Colitis
- Heat shock proteins research
- Genetic factors in colorectal cancer
- Helicobacter pylori-related gastroenterology studies
- Congenital Anomalies and Fetal Surgery
- Tracheal and airway disorders
- Intestinal Malrotation and Obstruction Disorders
- Hernia repair and management
- Eosinophilic Esophagitis
- Metastasis and carcinoma case studies
- Abdominal Trauma and Injuries
- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Vascular Malformations and Hemangiomas
University of Palermo
2008-2021
University of Palermo
2013-2021
Nuovo Ospedale San Giovanni di Dio
2020-2021
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2003-2018
Zero to Three
2015
BACKGROUND Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation tumor development and progression not well understood value as biomarker has been fully elucidated. In the current study, authors presented evidence supporting theory that Hsp60 potential therapeutic target patients with large bowel cancer. METHODS The studied population of 97 subjects, including controls. Immunomorphology, Western blot analysis, quantitative real‐time polymerase chain...
The aim of the present study was to evaluate expression heat shock protein 60 (HSP60), a mitochondrial matrix-associated belonging chaperonin family, in colorectal adenomas and cancers, comparing them normal colonic tissues hyperplastic polyps. We performed both immunohistochemistry Western blot analysis for HSP60. Immunohistochemistry resulted positive all tubular infiltrating adenocarcinomas. By contrast, polyps were negative. Quantitative showed that with different levels dysplasia did...
Ingestion of foreign bodies and food impaction represent the second most common endoscopic emergency after bleeding. The aim this paper is to report management outcomes in 67 patients admitted for suspected ingestion body between December 2012 2014.This retrospective study was conducted at Palermo University Hospitals, Italy, over a 2-year period. We reviewed patients' database (age, sex, type its anatomical location, treatments, as complications, success rates, mortalities).Foreign were...
We measured anti-transglutaminase (anti-tTG) antibody in the culture medium of intestinal biopsy specimens from patients with suspected celiac disease (CD) and evaluated relationship between production severity mucosal damage.We performed diagnostic testing for CD on 273 consecutive patients. In addition to routine histologic evaluation duodenal specimens, we assayed anti-tTG antibodies serum specimens.CD was diagnosed 191 Sensitivity specificity anti-endomysium (EmA) assays were 83% 85% 99%...
Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric (80%), presenting with upper gastrointestinal bleeding. We report first case of a man secondary aorto-duodenal fistula history persistent occlusive syndrome. A 59-year old who underwent an aortic-bi-femoral bypass 5 years ago, presented dyspepsia and biliary vomiting. Computed tomography scan showed in third duodenal segment presence inflammatory tissue air bubbles between duodenum prosthesis, adherent to duodenum. The patient...
Colonic lipomas are uncommon, benign, submucosal adipose tumors that usually asymptomatic. Large can cause symptoms such as constipation, abdominal pain, rectal bleeding and intussusception. We report the case of a 60-year-old man with history lower pain pseudoobstructive symptoms. Colonoscopy revealed large polypoid sessile lesion in sigma. used standardized technique polypectomy, preceded by injection dilute 5 ml polygelin epinephrine 1:10,000 solution, to fully resect colonic lipomas. The...
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on prevalence low bone mass density (BMD) NCWS. Our study aims to evaluate BMD NCWS patients and search for correlations with other clinical characteristics. This prospective observation 75 (63 women; median age 36 years) irritable bowel syndrome (IBS)-like symptoms, 65 IBS 50 celiac controls. Patients were recruited at two Internal Medicine...
Celiac disease (CD) diagnosis is becoming more difficult as patients with no intestinal histology lesions may also be suffering from CD.To evaluate the diagnostic accuracy of antiendomysium (EmA) assay in culture medium biopsies for CD diagnosis.The clinical charts 418 and 705 non-CD controls who had all undergone EmA were reviewed.EmA a higher sensitivity (98 vs. 80%) specificity (99 95%) than serum EmA/antibodies to tissue transglutaminase (anti-tTG) assay. All tested false-negatives...
Chronic anal fissure's (CAF) etiopathogenesis remain unclear. CAF of the posterior commissure (CAPF) are often characterized by internal sphincter (IAS) hypertonia. The treatment this disease aimed to reduce IAS Due high rate incontinence after LIS, employment preserving surgical techniques associated pharmacological sphincterotomy appears more sensible. aim our study is evaluate long-term results fissurectomy and anoplasty with V-Y cutaneous flap advancement 30 UI botulinum toxin injection...
Introduction. Herpes simplex esophagitis is well recognized in immunosuppressed subjects, but it infrequent immunocompetent patients. We present a case of HSE 53-year-old healthy man. Materials and Methods. The patient was admitted with dysphagia, odynophagia, retrosternal chest pain. An esophagogastroduodenoscopy revealed minute erosive area distal esophagus biopsies confirmed findings characteristic Simplex Virus infection. Results. patients treated high dose protonpump inhibitor,...
Objective. Persistent villous atrophy in patients with celiac disease (CD) on a gluten-free diet (GFD) is reported increasing frequency. The aim of this study was to evaluate possible association between persistent damage the villi and "atypical" gastrointestinal symptoms CD GFD. Material methods. Sixty-nine GFD were divided into two groups: Group A included 42 (6 M, 36 F, age range 17–62 years) undergoing esophagogastroduodenoscopies (EGDs) due presence symptoms; B 27 control 21 24–71 who...
Chronic constipation that is unresponsive to laxative treatment a severe illness, but children laxatives have been successfully treated with an elimination diet. We report the first cases of refractory chronic caused by food hypersensitivity in adults. Four patients who were high doses put on oligo-antigenic diet and underwent successive double-blind, placebo-controlled, challenges (DBPFC). Routine laboratory tests, immunological assays, colonoscopy, esophago-gastroduodenoscopy rectal...
To determine the complications and incidence of first second access-related vascular injuries induced by videolaparoscopic cholecistectomy.We retrospectively reviewed in 200 consecutive patients who underwent cholecistectomy from 2003 to 2005. One hundred one with placement radial expanding trocars were assigned into group A 99 pyramidal tipped B. All submitted open access according Hasson for trocar.Bleeding did not occur at intraoperative cannula-site A. However, it occurred 7 (7.1%) B, a...