- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Orthopedic Infections and Treatments
- Bone fractures and treatments
- Mesenchymal stem cell research
- Surgical site infection prevention
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Scoliosis diagnosis and treatment
- Management of metastatic bone disease
- Hematological disorders and diagnostics
- Spinal Cord Injury Research
- Bone and Joint Diseases
- Meningioma and schwannoma management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Anesthesia and Pain Management
- Periodontal Regeneration and Treatments
- Hip disorders and treatments
- Spinal Hematomas and Complications
- Neurofibromatosis and Schwannoma Cases
- Musculoskeletal pain and rehabilitation
- Nerve Injury and Rehabilitation
- Ultrasound Imaging and Elastography
Nara Medical University
2011-2022
Nara Prefecture General Medical Center
2016-2022
National Archives and Records Administration
2016-2018
Nara Medical University Hospital
2003-2011
Marrow mesenchymal cells (MSCs) contain stem and possess the ability to regenerate bone, cartilage, fibrous tissues. Here, we applied this regenerative intervertebral disc regeneration therapy in an attempt develop a new spinal surgery technique.We analyzed restoration of autologous MSCs markedly degenerated discs.Fusion for lumbar instability improves lumbago. However, fused discs lack natural physiologic functions discs. If can be regenerated repaired, then damage adjacent avoided. We...
OBJECTIVE Transplantation of bone marrow stromal cells (BMSCs) is a theoretical potential as therapeutic strategy in the treatment spinal cord injury (SCI). Although scaffold sometimes used for retaining transplanted damaged tissue, it also known to induce redundant immunoreactions during degradation processes. In this study, authors prepared cell sheets made BMSCs, which are transplantable without scaffold, and investigated their effects on axonal regeneration, glial scar formation,...
Study Design. A case-control study. Objective. The objective of this study is to identify biochemical markers for surgical site infection (SSI) in posterior instrumented spinal fusion that are not affected by operative circumstances and determine diagnostic cutoffs these markers. Summary Background Data. Numerous may be used early detection SSI; however, factors. Methods. We reviewed data on C-reactive protein level total white blood cell count differential before at 1, 4, 7 days...
In Brief Study Design. A prospective research. Objective. Compare the reliability of post-tetanic motor-evoked potential (p-MEP) monitoring in detection motor injury during spinal surgery with that conventional MEP (c-MEP). Summary Background Data. Myogenic MEPs are sensitive to suppression by anesthetics and neuromuscular blockade. Recently, we reported a new technique for recording, called “p-MEP” which amplitude can be enlarged tetanic stimulation peripheral nerve before transcranial...
Study Design Prospective study. Purpose The main purpose of this study was to clarify the range magnification errors on digital plain radiographs and determine if there is a correlation between body mass index (BMI) patient error. Overview Literature Most clinicians currently use radiography. This new method allows one access images measure lengths angles more easily than with past technologies. In addition, conventional radiography has errors. Although few articles mention in regards...
Study Design. Case report. Objectives. To describe a rarely reported type of upper thoracic spinal cord injury without vertebral bony lesion in two cases with multiple trauma. Summary Background Data. Because it is supported by the stiffness rib cage, spine has greater stability than cervical and lumbar regions, thus its fracture or dislocation less frequent. Nevertheless, when occurs, involvement severe concomitant injuries are frequently associated. Methods. Two who were suspected to have...
Retrospective cross-sectional study.To determine the prevalence of idiopathic scoliosis, define distribution curve magnitude, evaluate accuracy Moiré topography as a screening tool, and investigate cost-effectiveness our system.Early detection scoliosis provides opportunity for conservative treatment before deformity is noticeable. We believe that in schools useful detection; however, programs are controversial owing to over referral students who do not require further testing or follow-up....
Study Design Case-control study. Purpose To identify the characteristics of candidate indexes for early detection surgical site infection (SSI). Overview Literature SSI is a serious complication spinal instrumentation surgery. Early diagnosis and treatment are crucial welfare patient postoperation. Methods We retrospectively reviewed laboratory data patients who underwent posterior lumbar surgery degenerative spine disease. The sensitivity specificity six markers were calculated: greater...
Object The purpose of this study was to investigate the prevalence developmental canal stenosis in patients with cervical spondylotic myelopathy (CSM), and correlation between surgical results degree stenosis. Methods A total 112 who eventually had treatment for CSM were evaluated. Male whose sagittal spinal diameter < 14 mm females 13 even at one level classified as having Two groups used study; “positive” group (57 cases) included preoperatively, whereas “negative” (55 excluded such...
Recently, we reported a new technique to augment motor-evoked potentials (MEPs) under general anesthesia, posttetanic MEP (p-MEP), in which tetanic stimulation of the peripheral nerve before transcranial enlarged amplitudes MEPs from muscle innervated by subjected stimulation. In present study, tested whether left tibial can also muscles are not stimulation.Thirty patients undergoing spinal surgery propofol-fentanyl anesthesia with partial neuromuscular blockade were examined. For...
Case-control study.To identify laboratory markers for surgical site infection (SSI) in posterior lumbar decompression surgery, which are not affected by operative factors, and to determine the diagnostic cutoffs of these markers.Numerous used early detection SSI; however, may be factors.The study included 182 participants. They were divided into an SSI group (patients who developed deep n = 8) a no-SSI (n 174). We reviewed data on C-reactive protein level total white blood cell count...
Study Design Case control study. Purpose To identify the most significant laboratory marker for early detection of surgical site infection (SSI) using multiple logistic regression analysis. Overview Literature SSI is a serious complication spinal instrumentation surgery. Early diagnosis and treatment are crucial. Methods We retrospectively reviewed data patients who underwent posterior lumbar surgery degenerative disease from January 2003 to December 2014. Six markers were considered:...
In Brief Study Design. A retrospective study comparing cervical laminoplasty with or without muscle release for the treatment of myelopathy resulting from athetoid cerebral palsy. Objective. To assess effectiveness in Summary Background Data. While anterior and/or posterior spinal fusion has been generally accepted as necessary surgical due to palsy, several studies have shown relatively favorable results following laminoplasty. Better can be obtained by combining release. Methods....
To identify the temporal comparison of biochemical markers for early detection surgical site infection (SSI) following instrumented spinal fusion that are not affected by operative factors.We reviewed data on C-reactive protein level and total white blood cell count differential before at 1, 4, 7 days postoperatively. The 141 patients in our sample were divided into an SSI group (patients who developed deep SSI) a non-SSI group. We investigated peak or nadir value day identified those...
Case-control study.The aim of the present study was to identify physical findings useful for differentiating between cervical spondylotic amyotrophy (CSA) and rotator cuff tears prevent misdiagnosis CSA as a tear.CSA are often confused among patients presenting with difficulty in shoulder elevation.Twenty-five 27 were enrolled. We included five specific that observed both tear patients. The follows: (1) weakness deltoid muscle, (2) biceps (3) atrophy (4) (5) swallow-tail sign (assessment...
Skeletal diseases, such as nonunion and osteonecrosis, are now treatable with tissue engineering techniques. Single cell sheets called osteogenic matrix (OMCSs) grown from cultured bone marrow-derived mesenchymal stem cells show high potential; however, long preparation times currently limit their clinical application. Here, we report a cryopreservation OMCS transplantation method that shortens time. Cryopreserved rat OMCSs were prepared using slow- rapid-freezing methods, thawed,...
The in vivo osteogenic potential of autogenous cultured bone/ceramic constructs large animals or humans is unknown, and thus we performed a preliminary study this issue prior to clinical application. All cultured-bone/ceramic at 3 weeks after implantation dogs showed obvious histological bone formation within the ceramic pores. In many pores, HE staining decalcified specimens revealed thick lamellar on pore surface ceramic. On tissue, numerous active cuboidal osteoblasts were evident....