Xiaoyue Chang

ORCID: 0000-0002-7680-1184
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About
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Research Areas
  • Brucella: diagnosis, epidemiology, treatment
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacterial Infections and Vaccines
  • Leptospirosis research and findings
  • Respiratory viral infections research
  • Nosocomial Infections in ICU
  • Burkholderia infections and melioidosis
  • Pneumonia and Respiratory Infections
  • Antibiotic Resistance in Bacteria

Baotou Central Hospital
2023-2025

Inner Mongolia Medical University
2023

Inner Mongolia University of Science and Technology
2023

Baotou Medical College
2023

Ceftazidime-avibactam was approved in patients with hospital-acquired pneumonia (HAP), including ventilator-associated (VAP), based on the multinational Phase 3 REPROVE study. This study assessed efficacy and safety of ceftazidime-avibactam Chinese adults HAP/VAP. a 4, prospective, multi-centre, open-label study, conducted at 42 sites China. Patients HAP/VAP received 2.5 g by 2-hour IV infusion every 8 hours for 7-14 days. Primary endpoint clinical response test-of-cure (TOC) visit modified...

10.1016/j.jgar.2025.03.001 article EN cc-by-nc-nd Journal of Global Antimicrobial Resistance 2025-03-01

Nemonoxacin malate is a novel non-fluorinated quinolone for oral and intravenous (IV) administration. This phase 3 multicentre, randomised, double-blind, double-dummy, parallel-controlled clinical trial (NCT02205112) evaluated the efficacy safety of IV nemonoxacin versus levofloxacin treatment community-acquired pneumonia (CAP) in adult patients. The eligible patients were randomised to receive 500 mg or via infusion, once daily 7-14 days. primary endpoint was cure rate at test (TOC) visit...

10.1016/j.ijantimicag.2024.107235 article EN cc-by-nc-nd International Journal of Antimicrobial Agents 2024-06-07

Pleurisy and pleural effusion caused by Brucella infection are rare. However, clinicians lack an understanding of these possibilities, the underlying disorder is easy to misdiagnose. We report a 52-year-old male farmer who was admitted hospital with fever, chest pain, shortness breath. Closed drainage performed thoracocentesis, concentration adenosine deaminase (ADA) in fluid >45 U/L. Mononuclear cells accounted for 90% cells, pathology indicated large number lymphocytes. The clinical...

10.1177/03000605231187952 article EN cc-by-nc Journal of International Medical Research 2023-07-01
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