A5005007168- Viral Infections and Vectors
- Helicobacter pylori-related gastroenterology studies
- Urinary Tract Infections Management
- Infant Development and Preterm Care
- Physical Activity and Health
- Fire effects on ecosystems
- Pelvic floor disorders treatments
- Yersinia bacterium, plague, ectoparasites research
- Mosquito-borne diseases and control
- Urinary Bladder and Prostate Research
- Viral Infections and Outbreaks Research
- Neonatal and fetal brain pathology
- Liver Disease Diagnosis and Treatment
- Virus-based gene therapy research
- Vector-Borne Animal Diseases
- Liver Disease and Transplantation
- Eosinophilic Esophagitis
- Patient Satisfaction in Healthcare
- Nursing education and management
- Vector-borne infectious diseases
- Patient-Provider Communication in Healthcare
- Maternal and Perinatal Health Interventions
- Retinopathy of Prematurity Studies
- Pediatric Pain Management Techniques
- Ophthalmology and Visual Impairment Studies
University of Stirling
2010-2024
Vancouver General Hospital
2018
Western Isles Hospital
2018
James Cook University
2018
University of the Highlands and Islands
2018
University College London
2015
Moorfields Eye Hospital
2015
RMIT University
2015
The University of Adelaide
2010
University of Glasgow
2000-2001
Journal Article The Clinical Pathology of Crimean-Congo Hemorrhagic Fever Get access R. Swanepoel, Swanepoel Please address requests for reprints to Dr. Special Pathogens Unit, National Institute Virology, Sandringham 2131, Republic South Africa. Search other works by this author on: Oxford Academic PubMed Google Scholar D. E. Gill, Gill A. J. Shepherd, Shepherd P. Leman, Leman H. Mynhardt, Mynhardt S. Harvey Reviews Infectious Diseases, Volume 11, Issue Supplement_4, May-June 1989, Pages...
Following the diagnosis in 1981 of first case Crimean-Congo hemorrhagic fever (CCHF) South Africa, an antibody survey was undertaken on cattle sera to determine distribution virus and specific diagnostic tests were routinely applied specimens from suspected cases establish medical significance its presence. Antibody CCHF demonstrated by reversed passive hemagglutination-inhibition technique 2,460/8,667 (28%) 140/180 herds tested as well 347/763 (45%) 32/34 (94%) Zimbabwe. The found all major...
IgG and IgM antibodies became demonstrable by indirect immunofluorescence on days 7 to 9 of illness in 35 survivors Crimean-Congo hemorrhagic fever. Maximum titers antibody were usually attained the second third week illness. Titers declined gradually thereafter low or negative fourth month. In some patients increased markedly between 2 4 months after onset remained readily 3 years infection. Endogenous response was demonstrated only two 15 who died Techniques for demonstrating (in order...
<b>Background/aims:</b> Even in the absence of retinopathy prematurity (ROP), premature birth signals increased risk for abnormal refractive development. The present study examined relation between clinical factors and development among preterm infants without ROP. <b>Methods:</b> Cycloplegic refraction was measured at birth, term, 6, 12, 48 months corrected age a cohort 59 infants. Detailed perinatal history cranial ultrasound data were collected. 40 full term (plus or minus 2 weeks)...
Product substitution is a common dilemma in healthcare settings as products become unavailable due to supply chain shortages or other factors. Substitute can pose risks patient safety when not carefully selected. This study developed human factors-based heuristic evaluation tool help professionals make informed decisions choosing substitute products. The was through design sprint that involved factors experts and practitioners. Stakeholder led improvements categories. final proposed...
Journal Article Field and laboratory investigation of Crimean-Congo haemorrhagic fever virus (Nairovirus, family Bunyaviridae) infection in birds Get access A.J. Shepherd, Shepherd Department Virology, University the Witwatersrand Special Pathogens Unit, National Institute for Sandringham 2131, Republic South Africa Search other works by this author on: Oxford Academic PubMed Google Scholar R. Swanepoel, Swanepoel P.A. Leman, Leman S.P. Transactions The Royal Society Tropical Medicine...
Crimean-Congo hemorrhagic fever (CCHF) virus is becoming increasingly recognized as an important human pathogen in southern Africa. In order to determine the role of wild mammals natural ecology virus, sera from 3,772 87 species and 1,978 domestic dogs collected South Africa Zimbabwe between 1964 1985 were tested for antibody CCHF by reversed passive hemagglutination inhibition (RPHI) indirect immunofluorescence (IF). Antibody was found be highly prevalent large Orders Artiodactyla...
SUMMARY In order to determine the way in which vertebrates infected with Crimean-Congo haemorrhagic fever (CCHF) virus and potential ixodid tick vectors interact nature, immature adult ticks of several species were fed on viraemic mammals then assayed for content at varying times after feeding. CCHF was not isolated from six tested feeding as adults forms sheep viraemia 10 2·5−3·2 LD 50/ml, nor larval guinea-pigs white-tailed rats 1·9−2·7 50/ml. contrast, 152 pools engorged 5 that cattle...
The fluorescence focus assay and the plaque in CER cells were compared with mouse inoculation for isolation titration of Crimean-Congo hemorrhagic fever virus. similar sensitivity, but both produced 10- to 100-fold lower titers than did inoculation. For specimens from 26 patients South Africa, virus was isolated 20 by only 11 cell culturing. Although cultures less sensitive clinical specimens, they diagnostic results much more rapidly.
Aims: The aim of this study was to determine whether the widely adopted Institute Medicine’s dimensions quality capture current meaning in health care literature. Design: An integrative review utilised as there has been a multitude published papers defining relation care, therefore collective analysis may provide new insight and understanding. Method: Papers offering definition or conceptual understanding were identified by searching relevant databases. excluded according predefined...
To examine the association between prevalence of H. pylori colonisation and social deprivation in a sample children investigated hospital.A retrospective review hospital records all (n = 626) who underwent 13C-urea breath testing for suspected infection at Royal Hospital Sick Children, Glasgow, Scotland August 1995 to December 2002 was performed. Prevalence measured by test socioeconomic status Carstairs Morris index deprivation.The overall 26%. There highly significant positive poor (p <...
<h3>BACKGROUND</h3> Current diagnostic tests for <i>Helicobacter pylori</i> are invasive (endoscopy) or indirect (urea breath test, serology). <h3>AIMS</h3> To evaluate a new enzyme immunoassay (EIA) which detects <i>H pylori</i>antigens in faeces, by comparing its sensitivity and specificity children with the <sup>13</sup>C urea test (UBT). <h3>METHODS</h3> A total of 119 underwent UBT provided faecal sample antigen testing within seven days. After an overnight fast each child pretest...
Children with neurological impairments often have visual deficits that are difficult to quantify. We compared skills evaluated by carers results of a comprehensive assessment. Participants were 76 children mild profound intellectual and/or motor impairment (33 males, 43 females; age range 7mo–16y; mean 5y 1mo [SD 4y 2mo]) who completed inventory before attending special vision clinic. The included 16 questions about and responses familiar situations. Responses augmented taking structured...
This paper investigates the prognostic value of flash visual evoked potentials (VEPs) recorded in preterm infants at birth and term age with respect to severe neurological outcome. Flash VEPs were 81 (i.e. <35 weeks' gestation) repeated 56 these age. The assigned either a healthy or at-risk subgroup based on clinical factors. Normal ranges flash-VEP latencies, amplitudes, number components present obtained from 68 tested postnatally. results entire group compared normal any abnormalities...
The route of transmission Helicobacter pylori, which is usually acquired in childhood and one the most common bacterial infections humans, remains undetermined. Mapping distribution H. pylori genotypes within families could help to determine routes risk factors. Here we describe a noninvasive method for obtaining DNA isolates from feces children. Children presenting with gastrointestinal symptoms at Royal Hospital Sick were tested gastric colonization by using 13C-urea breath test (UBT)...
Vaginal examination (VE) and assessment of the cervix is currently considered to be gold standard for labour progress. It however inherently imprecise with studies indicating an overall accuracy determining diameter at between 48-56%. Furthermore, VEs can unpleasant, intrusive embarrassing women, are associated risk introducing infection. In light increasing concern world wide about use routine interventions in it may time consider alternative, less means assessing progress labour. The...