A5089710619- Sports injuries and prevention
- DNA Repair Mechanisms
- Muscle activation and electromyography studies
- Cerebral Palsy and Movement Disorders
- Foot and Ankle Surgery
- Spinal Cord Injury Research
- Sports Performance and Training
- Knee injuries and reconstruction techniques
- Transcranial Magnetic Stimulation Studies
- Lower Extremity Biomechanics and Pathologies
- Dye analysis and toxicity
- Motor Control and Adaptation
- Cytomegalovirus and herpesvirus research
- Natural Antidiabetic Agents Studies
- Thermal Regulation in Medicine
- Multiple Sclerosis Research Studies
- Various Chemistry Research Topics
- Infant Development and Preterm Care
- Effects of Radiation Exposure
- Intensive Care Unit Cognitive Disorders
- Enzyme-mediated dye degradation
- Balance, Gait, and Falls Prevention
- Enterobacteriaceae and Cronobacter Research
- Polyamine Metabolism and Applications
- Vitamin C and Antioxidants Research
Colorado State University
2024-2025
University of Iowa
2005-2024
Society of Critical Care Medicine
2022
University of Arkansas for Medical Sciences
2021
Muscular Dystrophy UK
2016
Imperial College London
2003
University of Wisconsin–Madison
1999-2002
Vanderbilt University
1997
Case Western Reserve University
1991
Journal Article Induction of mutations by replication malondialdehyde modified M13 DNA in Escherichia coil: determination the extent modification, genetic requirements for mutagenesis, and types induced Get access Mounir Benamira, Benamira 1A.B. Hancock Jr Memorial Laboratory Cancer Research, Departments Biochemistry, ChemistryNashville, TN 37232-0146, USA Search other works this author on: Oxford Academic PubMed Google Scholar Kristin Johnson, Johnson Ajai Chaudhary, Chaudhary Kaylon...
Repair of the exocyclic DNA adduct propanodeoxyguanosine (PdG) was assessed in both vivo and vitro assays. PdG site-specifically incorporated at position 6256 M13MB102 DNA, adducted viral genome electroporated into repair-proficient repair-deficient Escherichia coli strains. Comparable frequencies --> T A mutations were detected following replication genomes wild-type E. 4-fold increase transversions transitions observed strains deficient Uvr(A)BC-dependent nucleotide excision repair....
Skeletal muscle has traditionally been considered a "force generator": necessary for purposes of locomotion, but expendable non-ambulators who use wheelchairs, such as people with spinal cord injury (SCI). Active skeletal plays an indispensable role in regulating systemic metabolic functions, even paralysis, because severe osteoporosis, high tetanic forces induced frequency electrical stimulation may be risky some individuals. The purpose this study was to compare the physiologic properties...
The ability of the methyl-directed mismatch repair system to recognize and exocyclic adducts propanodeoxyguanosine (PdG) pyrimido[1,2-α]purin-10(3H)-one (M1G), major adduct derived from endogenous mutagen malondialdehyde, has been assessed both in vivo vitro. Both were site-specifically incorporated into M13MB102 DNA, adducted genomes electroporated wild-type or mutS-deficient Escherichia coli strains. A decrease mutations caused by was observed strains, suggesting that MutS binding blocking...
Accidental exposure to ionizing radiation may lead delayed effects of acute (DEARE) in many organ systems. Activated protein C (APC) is a known mitigator the syndrome. To examine role APC DEARE, we used transgenic mouse model with 2- 3-fold increased plasma levels (high APC, APCHi). Male and female APCHi mice wild-type littermates were exposed 9.5 Gy γ-rays their hind-legs (bone marrow) shielded from allow long-term survival. At 3 6 months after irradiation, cardiac function was measured...
After spinal cord injury (SCI), multiple adaptations occur that influence metabolic health and life quality. Prolonged sitting inactivity predispose people with SCI to body composition changes, such as increased visceral adipose tissue (VAT) thickness, which is often associated impaired glucose tolerance. Our goal understand whether VAT an index of leanness, and, secondarily, mobility methods tolerance for living SCI. A total 15 20 without had fasting oral tests (OGTT) thickness (leanness)...
Background: Anterior cruciate ligament (ACL) injuries often occur when an athlete experiences unexpected disruption, or perturbation, during sports. ACL injury rates may also be influenced by the menstrual cycle. Purpose: To determine whether training adaptations to knee control and muscle activity a perturbed single-leg squatting (SLS) task depend on cycle phase in female athletes. Study Design: Controlled laboratory study. Methods: A total of 21 healthy collegiate athletes (current former...
ADVERTISEMENT RETURN TO ISSUEPREVDemoNEXTFactors affecting reaction kinetics of glucose oxidaseKristin A. Johnson , Beth Kroa and Tony Yourey View Author Information Department Chemistry, University Wisconsin-Madison, Madison, WI 53706 Chemisty, Kutztown University, Kutztown, PA 19530Cite this: J. Chem. Educ. 2002, 79, 1, 74Publication Date (Web):January 2002Publication History Received3 August 2009Published online1 January 2002Published inissue 1...
Operant conditioning of a spinal monosynaptic pathway using the Hoffman reflex (H-reflex) is well established in animal and human studies. There subset within population (∼20% nonresponders) who are unable to up train this suggesting some distinct or unique identifying characteristics. Importantly, females, have nine times higher rate injury during performance activities than men, been understudied areas CNS neuroplasticity. Our long-term goal understand if innate ability rapidly H-reflex...
ADVERTISEMENT RETURN TO ISSUEPREVDemoNEXTA simple method for demonstrating enzyme kinetics using catalase from beef liver extractKristin A. Johnson and Willian C. Deese View Author Information Department of Chemistry, University Wisconsin - Madison, WI 53706 Louisiana Tech University, Ruston, LA 71272Cite this: J. Chem. Educ. 2000, 77, 11, 1451Publication Date (Web):November 1, 2000Publication History Received3 August 2009Published online1 November 2000Published inissue 1...
ADVERTISEMENT RETURN TO ISSUEPREVDemoNEXTA dramatic flame test demonstrationKristin A. Johnson and Rodney Schreiner View Author Information Department of Chemistry, University Wisconsin-Madison, Madison, WI 53706Cite this: J. Chem. Educ. 2001, 78, 5, 640Publication Date (Web):May 1, 2001Publication History Received3 August 2009Published online1 May 2001Published inissue 1 2001https://pubs.acs.org/doi/10.1021/ed078p640https://doi.org/10.1021/ed078p640research-articleACS PublicationsRequest...
Aim: To determine whether walking performance differed between people with multiple sclerosis (MS) who performed distinct types, volumes and intensities of exercise.
Trunk positioning and unexpected perturbations are high-risk conditions at the time of anterior cruciate ligament injury. The influence trunk on motor control responses to perturbation during dynamic performance is not known. We tested position feedforward feedback while performing a novel single-limb squatting task. also assessed degree that was predictive responses. In flexed condition, there were increased quadriceps (p < 0.026) gluteus medius long-latency reflexes 0.001) greater...
FMRI studies support that neuromuscular electrical stimulation can modulate the excitability of somatosensory cortex. We studied whether practice and quadriceps would enhance learning during a weight-bearing task. 20 healthy individuals (10 male) 8 control subjects participated in 2-day study. Day 1 consisted pretest, training session, post-test; day 2 bouts to muscles, post-test. The single limb squat task was performed at varying knee resistance target velocities random unexpected...
Exercise confers a multitude of benefits with limited adverse side effects, making it powerful "medication" for plethora diseases. In people living uncontrolled glucose levels, exercise can be an effective to assist in the management hyperglycemia. We sought survey healthcare providers (physicians and physical therapists) determine current state recommendation control issues. Healthcare were surveyed from six academic medical centers Midwest recommended parameters (type, frequency, duration,...
The Y-Balance Test (YBT), especially the posteromedial (PM) reach direction (PM-YBT), is able to identify dynamic postural control deficits in those who have ankle instability. However, there still exists a need understand how sensorimotor function at explains performance during PM-YBT.