A5023835337- Dental materials and restorations
- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Endodontics and Root Canal Treatments
- Bone and Dental Protein Studies
- Dental Trauma and Treatments
- Periodontal Regeneration and Treatments
- Dental Erosion and Treatment
- dental development and anomalies
- Dental Research and COVID-19
- Bone Tissue Engineering Materials
- Oral microbiology and periodontitis research
- Dental Anxiety and Anesthesia Techniques
- Oral and Maxillofacial Pathology
- Dental Education, Practice, Research
- Recycling and utilization of industrial and municipal waste in materials production
- Advanced ceramic materials synthesis
- Health and Medical Education
- Occupational health in dentistry
- Ultrasonics and Acoustic Wave Propagation
- Cultural Industries and Urban Development
- Building materials and conservation
- Family Business Performance and Succession
- Electrospun Nanofibers in Biomedical Applications
- Calcium Carbonate Crystallization and Inhibition
University of California, Los Angeles
2013-2024
Bayerisches Landesamt für Denkmalpflege
2019
Swiss Light Source
2012
University of Basel
2012
Paul Scherrer Institute
2012
University of California, Santa Barbara
2006
University of Southern California
1993-2005
American Academy of Implant Dentistry
1996-2003
Pacific Coast Imaging
2003
American Academy of Arts and Sciences
2003
Enamel forms the outer surface of teeth, which are complex shape and loaded in a multitude ways during function. has previously been assumed to be formed from discrete rods markedly aniostropic, but marked anisotropy might expected lead frequent fracture. Since fracture is not observed, we measured enamel organization using histology, imaging, mechanics modalities, compared with crystalline hydroxyapatite (Hap), its major component. was approximately three times tougher than geologic Hap,...
Proximal renal tubular acidosis (pRTA) is a syndrome caused by abnormal proximal tubule reabsorption of bicarbonate resulting in metabolic acidosis. Patients with mutations to the SLC4A4 gene (coding for sodium cotransporter NBCe1), have pRTA, growth delay, ocular defects, and enamel abnormalities. In an earlier report, we provided first evidence that cells, ameloblasts, express NBCe1 polarized fashion, thereby contributing trans-cellular transport. To determine whether plays critical role...
We have previously identified amelotin (AMTN) as a novel protein expressed predominantly during the late stages of dental enamel formation, but its role amelogenesis remains to be determined. In this study we generated transgenic mice that produce AMTN under amelogenin (Amel) gene promoter effect overexpression on formation in vivo. The specific secretory stage ameloblasts was confirmed by Western blot and immunohistochemistry. gross histological appearance or supporting cellular structures...
Natural teeth are graded in terms of translucency and strength. Graded zirconia materials now available with a higher yttria content on the top or enamel zone to increase surface lower bottom dentin Such could provide multiple advantages over uniform reduce need for porcelain veneering anterior artificial crowns; however, studies properties these lacking.
The dentino‐enamel junction (DEJ) couples a hard, brittle, stiff layer of enamel to underlying flexible and resilient dentin. Prior microscopic images have shown an abrupt demarcation between dentin; however, new data on protein expression suggests graded transition. In this study, Vickers microindentations reveal gradation in hardness with wide transitional zone across the DEJ region. Therefore, must be regarded as broad region two interacting tissues, not discrete interface. This may...